[High-dose urokinase for thrombolysis following replantation of severed limbs or fingers].

Objective: To study the efficacy of intravenous urokinase administration in preventing and treating vascular crisis in limb or finger replantation (LFR).

Methods: From September, 1999 to October, 2003, 158 patients underwent RSLF in whom 600,000 U of urokinase diluted in 30 ml saline was injected intravenously after blood vessel suture. An intermittent dose (200,000 U) per 12 h given postoperatively for maintenance.