Publications by authors named "Chao-Ying Wang"

Objective: Recent reports have demonstrated that a wider pulse pressure upon admission is correlated with heightened in-hospital mortality following spontaneous supratentorial intracerebral hemorrhage (ssICH). However, the underlying mechanism remains ambiguous. We investigated whether a wider pulse pressure was associated with hematoma expansion (HE).

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The advent of virtual reality (VR) in education offers unique possibilities for facilitating cooperative learning strategies, particularly in fields demanding intricate spatial understanding, such as gross anatomy. This study investigates the impact of integrating cooperative learning strategies within a VR-based gross anatomy curriculum, focusing on enhancing students' anatomy knowledge and skills. We analyzed the performance of two cohorts of first-year nursing students across five semesters (2016-2020), where traditional learning methods were used in the first three semesters (2016-2018), and a VR-based cooperative learning approach was adopted in the last two semesters (2019-2020).

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Endometriosis is an estrogen-dependent gynecological inflammatory condition that may lead to infertility and recurrent pelvic pain. The purpose of this research was to determine the efficacy and safety of -containing Chinese herbal medicine (CHM) combined with gonadotropin-releasing hormone agonist (GnRH-a) for postoperative endometriosis management. Eight databases were systematically searched before October 2021, including PubMed, Embase, Cochrane Library, Scopus, Web of Sceince, CNKI, VIP, and Wanfang.

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Objective: The present study aimed to explore whether a higher serum lactate dehydrogenase (sLDH) level on admission is associated with hematoma expansion (HE) in patients with primary intracerebral hemorrhage (ICH).

Methods: This single-center prospective observational study of patients with primary ICH aged 19 years or older was conducted at the Dehua County Hospital from January 2018 to May 2021. Clinical data and demographic information and outcomes were collected and analyzed.

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Article Synopsis
  • The study explored whether magnetic resonance spectroscopy (MRS) and diffusion-weighted imaging (DWI) could detect changes related to dysbaric osteonecrosis (DON) in the femoral heads of divers experiencing hip pain.
  • It involved 17 divers (9 with hip pain and 8 asymptomatic) alongside age- and gender-matched non-diving controls, focusing on comparing water content, lipid composition, and apparent diffusion coefficients (ADCs) in femoral heads.
  • Results showed that divers with hip pain had higher water content and unsaturation index of lipids, along with lower total lipid fraction, compared to asymptomatic divers and non-diving controls, indicating detectable dysbaric changes in their femoral heads.
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Lamk. var. Schauer is a species with medicinal and ornamental values.

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Article Synopsis
  • - The study aimed to examine changes in the vascularity of the infrapatellar fat pad (IPFP) in rats with chronic kidney disease (CKD) through advanced MRI techniques over time.
  • - Twelve male Sprague-Dawley rats underwent either a control procedure or 5/6 nephrectomy, with their IPFPs evaluated at different time intervals using DCE-MRI and T2* mapping.
  • - Results showed that rats with CKD exhibited decreased blood volume and permeability in the IPFP, as well as signs of adipocyte degeneration starting from 16 weeks, confirming the findings through histological analysis.
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Plants classified to the genus L. have important medicinal and ornamental value. Here, we report and characterize the complete chloroplast (cp) genome of to provide molecular basis for the further studies on the phylogeny analysis of this genus.

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Diels (Ericaceae) is a Chinese endemic and endangered species with high ornamental value. Here the complete chloroplast (cp) genome of was assembled and characterized. The cp genome is in a total length of 201,047 bp with the typical quadripartite structure of angiosperms, containing two inverted repeats (IRs) of 44,650 bp separated by a large single-copy (LSC) region of 109,134 bp and a small single-copy (SSC) region of 2613 bp.

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Objective: The relationship between neutrophil-lymphocyte ratio (NLR) and the occurrence of rebleeding in aneurysmal subarachnoid hemorrhage (aSAH) is poorly understood. Our study aimed to investigate the association between NLR on admission and rebleeding following aSAH.

Methods: Clinical and laboratorial data from patients with aSAH were retrospectively collected, including leukocyte, neutrophil, lymphocyte, and NLR.

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Background And Objective: To investigate the feasibility of histogram analysis of the T2*-based permeability parameter volume transfer constant (K) for glioma grading and to explore the diagnostic performance of the histogram analysis of K and blood plasma volume (v).

Methods: We recruited 31 and 11 patients with high- and low-grade gliomas, respectively. The histogram parameters of K and v, derived from the first-pass pharmacokinetic modeling based on the T2* dynamic susceptibility-weighted contrast-enhanced perfusion-weighted magnetic resonance imaging (T2* DSC-PW-MRI) from the entire tumor volume, were evaluated for differentiating glioma grades.

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The pathogenesis of chronic kidney disease (CKD) is multifactorial. In the progression of CKD arthropathy, arteriosclerosis may alter the knee subchondral bone marrow by altering blood flow through the bone vasculature. Herein, multi-parametric MRI assessment, including dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), magnetic resonance spectroscopy (MRS), MRI T2*, contrast enhanced MR angiography (CE-MRA), and micro-CT were applied in a rodent nephrectomy model to: 1) investigate the blood perfusion of subchondral bone marrow and its relationship to fat water content and trabeculation pattern in CKD and 2) demonstrate the feasibility of using multi-parametric MRI parameters as imaging biomarkers to evaluate the disease's progression.

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Lignocellulose is a polysaccharide and an abundant biomass resource that widely exists in grains, beans, rice, and their by-products. Over 10 million tons of lignocellulose resources and processing products are produced every year in China. Three recombinant Y.

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Objective: IL-26 has been shown to have high expression in RA. However, the effects of IL-26 on bone destruction in RA have not been evaluated. The aim of this study was to investigate the effects and mechanisms of IL-26 on RANK ligand (RANKL)-induced osteoclastogenesis.

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The Hoffa fat pad (infrapatellar fat pad) is a source of post-traumatic anterior knee pain, and Hoffa disease is a syndrome leading to chronic inflammation of the fat pad. Herein, change in T2* relaxation time of the fat pad was measured in a rodent anterior cruciate ligament transection (ACLX) model in order to (i) examine the causal relationship of anterior cruciate ligament (ACL) deficiency and Hoffa disease and (ii) demonstrate the feasibility of using T2* as an imaging biomarker to monitor disease progression. Three groups of male Sprague Dawley rats (n = 6 each group), received either (i) no intervention; (ii) sham surgery at the right knee; or (iii) right ACLX.

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Three water treatments (control, CK; continuous flooding, CF; and periodic flooding, PF) were installed to simulate the soil moisture change of the riparian zone in the Three Gorges Reservoir (TGR) region of China to study the physiological and ecological adaptation mechanisms of the native plant species Pterocarya stenoptera seedlings to the soil moisture change. All the water treatments had significant effects on the photosynthesis, biomass accumulation, and growth of the P. stenoptera seedlings.

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Background And Purpose: Brain enhancement on contrast-enhanced T1-weighted imaging (CET1-WI) after ischemic stroke is generally accepted as an indicator of the blood-brain barrier disruption. However, this phenomenon usually starts to become visible at the subacute phase. The purpose of this study was to evaluate the time-course profiles of K(trans), cerebral blood volume (vp), and CET1-WI with early detection of blood-brain barrier changes on K(trans) maps and their role for prediction of subsequent hemorrhagic transformation in acute middle cerebral arterial infarct.

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Purpose: The magnetic resonance (MR) T2 value of cartilage is a reliable indicator of tissue properties and therefore may be used as an objective diagnostic tool in early meniscal degeneration. The purpose of this study was to investigate age, gender, location, and zonal differences in MR T2 value of the posterior horns of knee menisci in asymptomatic subjects.

Methods: Sixty asymptomatic volunteers (30 men and 30 women) were enrolled and divided into three different age groups: 20-34, 35-49 and 50-70 years.

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Purpose: To determine changes in expression of transforming growth factor β-2 (TGF-β2) and basic fibroblast growth factor (bFGF) in scleral desmocytes from anterior and posterior portions of experimentally-induced myopic eyes of guinea pigs.

Methods: Three groups (n = 10) of 2-week-old guinea pigs were used to develop concave lens-induced myopia (LIM) in one eye via the out-of-focus method for 6, 15, or 30 days respectively, while the other eye in each guinea pig served as the self-control (SC). After myopia induction, lenses were removed, and scleral fibroblasts were cultured and passaged twice.

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Objective: To investigate occupational health status in migrant female workers in artificial gem cottages in Guangxi and to provide reference evidence for drawing up countermeasures to protect migrant female workers from occupational hazards.

Methods: Two thousands and ninety five migrant female workers in artificial gem manufacturing cottages in Wuzhou City, Guangxi Province, were randomly recruited to participate in the investigation. The standardized occupational health questionnaires were used to collect the information of demographic characteristics, occupational exposure and medical symptoms by interviewing with persons.

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Background: The study aims to determine the changes in the biomechanical properties of the anterior and extreme posterior portions of experimental near-sighted eyes by examining the mechanical behavior of guinea pig scleral desmocytes, thus finding a new approach to the pathogenesis of myopia and their corresponding therapies.

Methods: Guinea pigs (2 weeks old) were numbered and assigned into three groups (A, B, and C) with ten guinea pigs each. Concave lens-induced myopic (LIM) animal models were prepared via the out-of-focus method.

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Purpose: To investigate the effects of 3,4-methylenedioxymethamphetamine (MDMA, commonly known as "ecstasy") on the alterations of brain metabolites and anatomic tissue integrity related to the function of the basal ganglia-thalamocortical circuit by using proton magnetic resonance (MR) spectroscopy and diffusion-tensor MR imaging.

Materials And Methods: This study was approved by a local institutional review board, and written informed consent was obtained from all subjects. Thirty-one long-term (>1 year) MDMA users and 33 healthy subjects were enrolled.

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Purpose: To investigate quantitatively the topographic perfusion characteristics of the adenohypophysis by using dynamic contrast material-enhanced magnetic resonance (MR) imaging in a subgroup of patients with idiopathic growth hormone deficiency (IGHD) and with normal-appearing pituitary morphology on MR images.

Materials And Methods: This HIPAA-compliant, prospective study was approved by an institutional review board, and informed consent was obtained for all patients. Twenty-five patients (mean age, 10.

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Background And Purpose: Although isotropic diffusion-weighted imaging (isoDWI) is very sensitive to the detection of acute ischemic stroke, it may occasionally show diffusion negative result in hyper-acute stroke. We hypothesize that high diffusion contrast diffusion trace-weighted image with enhanced T2 may improve stroke lesion conspicuity.

Methods: Five hyper acute stroke patients (M:F=0:5, average age=61.

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We aimed to quantitatively investigate the alteration of parotid perfusion after irradiation using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) based on a two-compartment tracer kinetic model. This study enrolled 19 patients (53.2 +/- 14.

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