Publications by authors named "Chao-Wei Zhou"
Introduction: Postoperative pulmonary complications (PPCs) occur after up to 60% of non-cardiac thoracic surgery (NCTS), especially for multimorbid elderly patients. Nevertheless, current risk prediction models for PPCs have major limitations regarding derivation and validation, and do not account for the specific risks of NCTS patients. Well-founded and externally validated models specific to elderly NCTS patients are warranted to inform consent and treatment decisions.
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- The Qinghai-Tibet Plateau (QTP) is a key area for studying how high-altitude environments affect fish genome evolution and adaptation, especially for the critically endangered ancient fish species endemic to the region.
- Recent findings indicate that genome alterations, such as major bursts of transposons and expansions in histone genes, correlate with significant geological and climatic shifts during the QTP's formation, highlighting the impact of past events on genetic evolution.
- Population studies reveal that ancestral fish populations experienced two major declines in number around 2.6 million and 10,000 years ago, aligning with major glacial periods, suggesting that past environmental changes severely affected fish habitats, limiting migration and resulting in reduced genetic diversity.
Fish morphological phenotypes are important resources in artificial breeding, functional gene mapping, and population-based studies in aquaculture and ecology. Traditional morphological measurement of phenotypes is rather expensive in terms of time and labor. More importantly, manual measurement is highly dependent on operational experience, which can lead to subjective phenotyping results.
View Article and Find Full Text PDFThe Chinese longsnout catfish ( Günther) is one of the most economically important freshwater fish in China. As wild populations have declined sharply in recent years, it is also a valuable model for research on sexual dimorphism, comparative biology, and conservation. However, the current lack of high-quality chromosome-level genome information for the species hinders the advancement of comparative genomic analysis and evolutionary studies.
View Article and Find Full Text PDFAnimal genomes in the Qinghai-Tibetan Plateau provide valuable resources for scientists to understand the molecular mechanism of environmental adaptation. Tibetan fish species play essential roles in the local ecology; however, the genomic information for native fishes was still insufficient. Oxygymnocypris stewartii, belonging to Oxygymnocypris genus, Schizothoracinae subfamily, is a native fish in the Tibetan plateau living within the elevation from roughly 3,000 m to 4,200 m.
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- Ghrelin is a crucial hormone for regulating feeding in mammals and fish, and this study focused on cloning the preproghrelin cDNA sequence in the gut of the fish species Schizothorax prenanti.
- The preproghrelin gene was found to be strongly expressed in both the gut and brain, with expression detectable during embryonic development and in unfertilized eggs, indicating its potential role as maternal mRNA.
- An experiment showed that ghrelin mRNA levels decreased significantly after feeding, suggesting that food intake influences ghrelin regulation, highlighting the need for further research on its specific functions in S. prenanti.
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- Agouti-related protein (AgRP) is a key neuropeptide that regulates feeding in both mammals and fish, and this study focused on the cloning of its full-length cDNA sequence in the cyprinid fish Schizothorax prenanti.
- The AgRP gene, which encodes a 126-amino acid protein, was found to be highly expressed in the brain and was present in embryos and unfertilized eggs.
- Research indicated that AgRP expression significantly increased during short-term fasting (3-4 hours) in fish, while long-term fasting (14 days) did not affect its mRNA levels, suggesting AgRP plays a role in short-term feeding regulation and other physiological functions.