[Research Hotspots on Systemic Lupus Erythematosus in Pregnancy Based on Bibliometrics].

Objective To explore the research hotspots on systemic lupus erythematosus (SLE) in pregnancy based on the bibliometric analysis of the related articles published from 2018 to 2023 and provide directions for the future research in this field. Methods PubMed,Web of Science,and Embase were searched for the articles on SLE in pregnancy that were published from January 1,2018 to December 31,2023.VOSviewer was used to visualize the high-frequency keywords in the selected articles.

Delivery room resuscitation and short-term outcomes of extremely preterm and extremely low birth weight infants: a multicenter survey in North China.

Background: Delivery room resuscitation assists preterm infants, especially extremely preterm infants (EPI) and extremely low birth weight infants (ELBWI), in breathing support, while it potentially exerts a negative impact on the lungs and outcomes of preterm infants. This study aimed to assess delivery room resuscitation and discharge outcomes of EPI and ELBWI in China.

Methods: The clinical data of EPI (gestational age [GA] <28 weeks) and ELBWI (birth weight [BW] <1000 g), admitted within 72 h of birth in 33 neonatal intensive care units from five provinces and cities in North China between 2017 and 2018, were analyzed.

[Perinatal conditions of late preterm twins versus early term twins].

Objective: To study the perinatal complications of late preterm twins (LPTs) versus early term twins (ETTs).

Methods: A retrospective analysis was performed for the complications of 246 LPTs, 496 ETTs, and their mothers. The risk factors for late preterm birth were analyzed.

[Effect and safety of intensive phototherapy in treatment of neonatal hyperbilirubinemia].

Objective: To study the effect and safety of intensive phototherapy in the treatment of neonatal hyperbilirubinemia.

Methods: A total of 144 neonates with neonatal hyperbilirubinemia were randomly and prospectively divided into intensive phototherapy group and conventional phototherapy group, with 72 neonates in each group. The therapeutic effect and incidence of complications were compared between the two groups.

Perinatal risk factors and neonatal complications in discordant twins admitted to the neonatal intensive care unit.

Background: Many studies have shown a relationship between birth weight discordance and adverse perinatal outcomes. This study aimed to investigate the perinatal risk factors and neonatal complications of discordant twins who are admitted to the neonatal intensive care unit.

Methods: A total of 87 sets of twins were enrolled in this retrospective study, of which 22 sets were discordant twins and 65 sets were concordant twins.

[The influence of preventive iron supplementation to iron nutritional status in breastfed infants].

Objective: To analyze the effects to iron status who were given preventive iron supplements for two months from when they were breast-fed to four-month-old.

Methods: A total of 123 infants in four-month-old age who were breast-fed were randomly divided into iron supplementation group (63 cases) and control group (60 cases), iron supplementation group was supplied with low-dose iron (1 mg×kg⁻¹×d⁻¹) for two months with no intervention for control group. Blood samples were collected to test C reactive protein and iron status indicators in six-month-old age group infants, and the growth indices were measured and compared on the gender difference of iron status at and 6 months.

[Thrombocytopenia in pregnancy and neonatal outcomes].

Objective: To study the relationship between thrombocytopenia in pregnancy associated with various causes and neonatal outcomes.

Methods: Medical records of 140 pregnant women with thrombocytopenia in pregnancy and the neonatal outcomes from January 2009 to December 2010 were reviewed retrospectively. The pregnant women were classified into four groups according to the causes of thrombocytopenia: gestational thrombocytopenia (GT; n=94), pregnancy with immune thrombocytopenic purpura (ITP; n=30), pregnancy with other hematological disease (aplastic anemia or myelodysplastic syndrome; n=12), and other causes (n=4): pregnancy induced hypertension syndrome, pregnancy with systemic lupus erythematosus, and pregnancy with alcoholic cirrhosis.

[Risk factors for preterm birth and complications in 287 late preterm infants].

Objective: To investigate the risk factors for preterm birth and complications in late preterm infants.

Methods: The clinical data of 287 late preterm infants were retrospectively studied. Two hundred and eighty-eight term infants served as the control group.

[Effects of receptor-interacting protein 140 gene knockdown on the proliferation of microglioma cells: experiment with rat microglioma cells].

Objective: To investigate the effects of receptor-interacting protein (RIP)140 gene knockdown on the proliferation of microglioma cells.

Methods: Mouse microglioma cells of the line BV-2 were cultured and transfected with 2 kinds of recombinant RIP140-shRNA plasmids (V2MM-71674 and V2MM-71080) or blank plasmid MSCV-EGFP. Real-time PCR and Western blotting were used to detect the mRNA and protein expression of RIP140; and the cell proliferation was detected by MTT assay.

[Expression profile of receptor-interacting protein 140 in the brain: experiment with prenatal and postnatal mice].

Objective: To investigate the expression of receptor-interacting protein of 140,000 (RIP140) in the developmental brain.

Methods: The brain tissues of 15-day-old and 20-day-old fetal Balb/c mice and 1, 7, 14, 28, 42, and 56-day-old postnatal mice were collected. The expression of RIP140 was examined by immunohistochemistry.