Publications by authors named "Chao-Lan Sheng"
ACS Synth Biol
September 2024
Article Synopsis
- Phenazine-based small molecules have unique biological properties and potential uses in medicine and energy, but their natural production processes are not well understood.
- The study successfully cloned and expressed the lomofungin biosynthetic gene cluster, leading to the identification of eight phenazine derivatives, including two new types.
- Lomofungin was found to be effective in inhibiting human cancer cells, providing valuable information for developing new phenazine derivatives through biosynthesis.
