Publications by authors named "Chao-Jun Xue"
The synergistic anti-tumor effect of schisandrin B and apatinib.
J Asian Nat Prod Res
September 2020
Article Synopsis
- The study examined the combined effects of schisandrin B (Sch.B) and apatinib on tumor cells, finding that Sch.B boosted the effectiveness of apatinib in inhibiting cancer cell growth.
- Sch.B helped to stop the cell cycle in the G0/G1 phase, reduced cell migration and invasion, and increased cancer cell death when used with apatinib.
- Results showed potential therapeutic benefits for using both Sch.B and apatinib together in treating gastric cancer (GC) progression.
Metformin is the most commonly prescibed drug for type 2 diabetes mellitus as it is inexpensive, safe, and efficient in ameliorating hyperglycemia and hyperinsulinemia. Numerous epidemiological studies indicate that diabetic population is not only at increased risk of cardiovascular complications, but also at substantially higher risk of many forms of malignancies. Meanwhile, epidemiological and clinical observation studies have shown that metformin use reduces risk of cancer in patients with type 2 diabetes mellitus and improves prognosis and survival rate of the cancer patients.
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