Publications by authors named "Chao-Jing Zhang"
The mutual regulation between hydrogen sulfide (HS) and microRNA (miRNA) is involved in the development of many diseases, including cancer, cardiovascular disease, inflammatory disease, and high-risk pregnancy. Abnormal expressions of endogenous HS-producing enzyme and miRNA in tissues and cells often indicate the occurrence of diseases, so the maintenance of their normal levels in the body can mitigate damages caused by various factors. Many studies have found that HS can promote the migration, invasion, and proliferation of cancer cells by regulating the expression of miRNA, while many HS donors can inhibit cancer progression by interfering with the proliferation, apoptosis, cell cycle, metastasis, and angiogenesis of cancer cells.
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- The rise of age-related diseases has made it crucial to develop effective treatments, highlighting the urgency of finding new drugs.
- * Hydrogen sulfide (HS) plays a vital role in regulating various physiological processes, including anti-oxidation, anti-inflammation, and cell activities like proliferation and apoptosis.
- * The review discusses the potential of HS as a therapeutic target for addressing the pathogenesis and treatment of age-related diseases.
The role of hydrogen sulphide (H S) in angiogenesis has been widely demonstrated. Vascular endothelial growth factor (VEGF) plays an important role in H S-induced angiogenesis. H S promotes angiogenesis by upregulating VEGF via pro-angiogenic signal transduction.
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