Effects of Homogenization Heat Treatment on the Fe Micro-Segregation in Ti-1023 Titanium Alloy.

The segregation of the Fe element in Ti-10V-2Fe-3Al titanium alloy (Ti-1023) can lead to the generation of beta flecks, which seriously affects the performance of Ti-1023 products. During the heat treatment (HT) process at a high temperature, the Fe element in Ti-1023 ingots will migrate, making its distribution more uniform and reducing the segregation index. In this paper, the control of Fe micro-segregation in Ti-1023 ingots by homogenization HT was investigated.

Management of granulomatous lobular mastitis: an international multidisciplinary consensus (2021 edition).

Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care for patients with inflammatory disorders of the breast. This consensus is summarized to establish evidence-based recommendations for the management of GLM.

LncRNA SNHG5 promotes the glycolysis and proliferation of breast cancer cell through regulating BACH1 via targeting miR-299.

Background: Breast cancer (BC) is one of the most common malignant tumors in women. Accumulating studies have been reported that long non-coding RNA (lncRNA) SNHG5 is highly expressed in BC. However, the specific molecular mechanism of SNHG5 in BC is unclear.

Kaempferol blocks neutrophil extracellular traps formation and reduces tumour metastasis by inhibiting ROS-PAD4 pathway.

Kaempferol (kaem) is a dietary flavonoid found in a variety of fruits and vegetables. The inhibitory effects of kaem on primary tumour growth have been extensively investigated; however, its effects on tumour metastasis are largely unknown. In the present study, we found that kaem significantly suppresses both primary tumour growth and lung metastasis in mouse breast tumour model.

Noninvasive and real-time pharmacokinetics imaging of polymeric nanoagents in the thoracoepigastric vein networks of living mice.

Noninvasive and real-time visualization of the thoracoepigastric veins (TVs) of living mice was demonstrated by using two-photon excitation (TPE) optical imaging with a Eu-luminescent polymeric nanoagent as the angiographic contrast. The spatiotemporal evolution of the polymeric nanoagent in TVs was monitored for up to 2 h by TPE time-resolved (TPE-TR) bioimaging, which is free from the interference of tissue autofluorescence. A wide field-of-view covering the thoracoabdominal region allowed the visualization of the entire TV network with an imaging depth of 1 to 2 mm and a lateral resolution of 80 μm at submillimeter.

Uptake and Translocation of Styrene Maleic Anhydride Nanoparticles in Murraya exotica Plants As Revealed by Noninvasive, Real-Time Optical Bioimaging.

This work reports the in vivo uptake and translocation of PNPs in the one-year grown terrestrial plant, Murraya exotica ( M. exotica), as investigated by two-photon excitation and time-resolved (TPE-TR) optical imaging with a large field of view (FOV, 32 × 32 mm) in a noninvasive and real-time manner. The PNPs (⟨ R⟩ = 12 ± 4.

Wide field of view, real time bioimaging apparatus for noninvasive analysis of nanocarrier pharmacokinetics in living model animals.

Understanding nanocarrier pharmacokinetics is crucial for the emerging nanopharmacy, which highly demands noninvasive and real-time visualization of the dynamics of nanocarriers. To this end, we have developed a 2-photon excitation and time-resolved (TPE-TR) bioimaging apparatus for the analysis of the spatial distribution and temporal evolution of nanocarriers in living model animals. The specific polymeric nanocarrier, Eu@pmma-maa doped with Eu-complexes luminescing in long persistence at ∼615 nm upon near-infrared 2-photon excitation, allows the complete rejection of tissue autofluorescence by selective luminescence detection.

Effect of initial solution pH on photo-induced reductive decomposition of perfluorooctanoic acid.

The effects of initial solution pH on the decomposition of perfluorooctanoic acid (PFOA) with hydrated electrons as reductant were investigated. The reductive decomposition of PFOA depends strongly on the solution pH. In the pH range of 5.

Short- and long-chain perfluorinated acids in sewage sludge from Shanghai, China.

Perfluorinated acids (PFAs) are the subject of increasingly intense environmental research. In this study, sewage sludge samples were collected from 25 wastewater treatment plants (WWTPs) in Shanghai, China to evaluate the levels and profile of C3-C14 PFAs. The results showed a ubiquitous PFAs contamination of sewage sludge in Shanghai with the total PFAs (∑PFAs) range of 126-809 ng g(-1)dw.

[Method development for analysis of short-and long-chain perfluorocarboxylates in sewage].

A method using weak anion exchange cartridge for solid phase extraction before high performance liquid chromatography-negative electronspray ionization-tandem mass spectrometry [WAX-SPE + HPLC-ESI(-)-MS/MS] detection has been developed to measure C2-C14 perfluorocarboxylates (PFCAs) in sewages. When the weak anion exchange (WAX) cartridges were used for solid phase extraction (SPE), the better recoveries of short- and long-chain PFCAs (C2-C14) were achieved as the sewage samples were acidified to pH = 3.0 by formic acid, 2% formic acid was used for washing solvent and 1% ammonium hydroxide in methanol was used for elution solvent.

[Toxicological study of PFOS/PFOA to zebrafish (Danio rerio) embryos].

Acute toxicity of PFOS/PFOA to zebrafish (Danio rerio) and development effects to zebrafish embryo were examined using a zebrafish embryo test. PFOS/PFOA showed remarkably toxicity effects on zebrafish. The LC50 (48 h) values are 1 005 mg/L for PFOA, 107 mg/L for PFOS, while the LC50 (96 h) values are 499 mg/L for PFOA, 71 mg/L for PFOS.

[Sorption behavior of bisphenol A on anaerobic sludge].

Batch experiments were conducted to investigate the sorption behavior of bisphenol A (BPA) with low concentration on anaerobic sludge. The autoclaved inactivated sludge was used to minimize the influence of degradation of activated sludge. The results showed that the sorption of BPA on anaerobic sludge was a quick process.

[Studies on the electron transfer between etoposide (VP-16) and DNA].

In the present study, the electron transfer between Etoposide (VP-16) and GMP or DNA was investigated using pulse radiolysis and circular dichroism technology. The electron transfer between VP-16 and GMP was found, and the reaction rate constant was determined as 3.16 x 10(7) L x mol(-1) x s(-1) by pulse radiolysis.

[Biodegradability and degradation mechanism of 3-fluorophenol by the activated sludge].

An acclimated activated sludge was examined for its ability to degrade 3-fluorophenol in aerobic batch cultures. The result indicated that the organism degrades up to 100 mg/L 3-fluorophenol completely with approximately 100% fluoride anion release within 16 h. 3-Fluorophenol can serve as the sole carbon source and energy source for the organism.