Publications by authors named "Chao-Hui He"

Article Synopsis
  • The study aimed to assess the effectiveness and safety of magnetically guided capsule endoscopy with a detachable string (ds-MCE) for identifying and evaluating oesophagogastric varices in adults with cirrhosis.
  • Conducted across 14 medical centers in China, the study involved 607 participants who underwent both ds-MCE and oesophagogastroduodenoscopy (OGD) to compare accuracy.
  • The results showed that ds-MCE had high sensitivity (97.5%) and specificity (97.8%) for detecting oesophagogastric varices, and it effectively identified high-risk variants with diagnostic accuracy rates exceeding 96%. *
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With the development and generalization of endoscopic technology and screening, clinical application of magnetically controlled capsule gastroscopy (MCCG) has been increasing. In recent years, various types of MCCG are used globally. Therefore, establishing relevant guidelines on MCCG is of great significance.

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Objective: To investigate the effects of glucocorticoid receptor agonists on hyperalgesia in rats with neuropathic pain (NPP) by regulating nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)/interleukin-1β (IL-1β) pathway and its mechanisms.

Methods: Forty SD rats were divided into control group, NPP model group, NPP treated with NLRP3 inhibitor group and dexamethasone treatment group with 10 rats in each group. The NPP rat model was induced by vincristine.

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Article Synopsis
  • This study focuses on the safety and effectiveness of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) in older patients (over 65) with chronic pancreatitis, contrasting it with younger patients.
  • The results showed that the success rates of ERCP were comparable between the elderly and younger groups, but older patients experienced a higher rate of moderate to severe complications.
  • Specific factors like being female and having conditions like pancreas divisum were linked to an increased risk of post-ERCP pancreatitis in geriatric patients.
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Objectives: Sinistral portal hypertension (SPH) is an uncommon complication of chronic pancreatitis (CP) and can result in severe gastrointestinal bleeding. The aim of this study was to determine the prevalence and the potential risk factors for SPH and related gastrointestinal variceal bleeding in patients with CP.

Methods: We retrospectively reviewed all patients with SPH due to CP admitted to our hospital from July 2014 to June 2019 in this case-control study.

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Constipation, mainly manifesting as abdominal discomfort and painful defecation, is considered as a chronic disorder. Due to a lack of effective therapy, it imposes a significant economic burden and greatly impacts patients' quality of life which prompt searches for new, original approaches. Based on the research of vibrating capsule (VC) carried out by Ron et al.

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The interfacial interaction of uranium mononitride (UN) with water from the environment unavoidably leads to corrosion of nuclear fuels, which affects a lot of processes in the nuclear fuel cycle. In this work, the microscopic adsorption behaviors of water on the UN(001) surface as well as water dissociation and accompanying H2 formation mechanisms have been investigated on the basis of DFT+U calculations and ab initio atomistic thermodynamics. For adsorption of one H2O monomer, the predicted adsorption energies are -0.

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