The Competitive Endogenous RNA (ceRNA) Regulation in Porcine Alveolar Macrophages (3D4/21) Infected by Swine Influenza Virus (H1N1 and H3N2).

H1N1 and H3N2 are the two most common subtypes of swine influenza virus (SIV). They not only endanger the pig industry, but are also a huge risk of zoonotic diseases. However, the molecular mechanism and regulatory network of pigs (hosts) against influenza virus infection are still unclear.

miR-215 Targeting Novel Genes , 1 and Regulates the Resistance to F18 in Piglets.

Previous research has revealed that miR-215 might be an important miRNA regulating weaned piglets' resistance to ( F18. In this study, target genes of miR-215 were identified by RNA-seq, bioinformatics analysis and dual luciferase detection. The relationship between target genes and infection was explored by RNAi technology, combined with stimulation and enzyme linked immunosorbent assay (ELISA) detection.

Insight into the molecular mechanism of miR-192 regulating resistance in piglets.

MicroRNAs (miRNAs) have important roles in many cellular processes, including cell proliferation, growth and development, and disease control. Previous study demonstrated that the expression of two highly homologous miRNAs (miR-192 and miR-215) was up-regulated in weaned piglets with F18 infection. However, the potential molecular mechanism of miR-192 in regulating infection remains unclear in pigs.