Chlorogenic acid mitigates avian pathogenic Escherichia coli-induced intestinal barrier damage in broiler chickens via anti-inflammatory and antioxidant effects: CHLOROGENIC ACID AND BROILER CHICKENS.

This study was conducted to investigate the protective effects of chlorogenic acid (CGA) on intestinal health in broilers challenged with avian pathogenic Escherichia coli (APEC). One hundred and eighty one-day-old male broiler chicks were divided into three groups with six replicates of ten chicks each for a 21-day trial. The birds in the control and APEC groups were fed a basal diet, while birds in the CGA-treated group received a basal diet supplemented with 1000 mg/kg of CGA.

Profiles of moral sensitivity and their associated factors in nursing students: A latent profile analysis.

Aim: This study was conducted to identify group profiles in moral sensitivity among Chinese nursing students and examine the factors associated with moral sensitivity subgroups.

Background: Moral sensitivity is a precondition for ethical decision making. Developing this sensitivity equips nursing students with the skills to identify and respond appropriately to ethical dilemmas, which are essential as they prepare to enter clinical settings.

Clinical study on the optimal rotational stimulation for the unilateral centrifugation subjective visual vertical test.

Objective: To investigate the optimal stimulation intensity and reference range of the unilateral centrifugation subjective visual vertical (UC-SVV) test and to fill the technical gap in otolithic function evaluation in patients with peripheral vestibular diseases.

Method: Forty healthy subjects (median age 28 years) underwent a UC-SVV test at rotation speeds of 60, 120, 180, and 240 deg./s using the Neuro Kinetics Inc.

Severe pneumonia caused by in a patient with bronchiectasis and IgA nephropathy: a case report.

Background: species are rare opportunistic pathogens in the clinic, with strong invasiveness and dissemination, that can cause serious pulmonary infection, especially in immunocompromised patients, chronic lung diseases and hormone use, and is easy to be missed and misdiagnosed, preventing patients from obtaining timely and effective treatment, resulting in a high mortality rate.

Case Presentation: Here, we present a rare case of a patient with chronic bronchiectasis and IgA nephropathy who developed pneumonia shortly after hormone therapy. The patient presented with tongue and lip ulcers, chest distress, cough, expectoration, and fever as the initial symptoms, which were extremely similar to common bacterial pulmonary infections.

Effects of Metarhizium anisopliae on lethality, transfer, behavior, and physiology in Eucryptorrhynchus scrobiculatus and E. brandti (Coleoptera: Curculionidae).

Eucryptorrhynchus scrobiculatus (Motschulsky) and E. brandti (Harold) are 2 serious pests inflicting damage on Ailanthus altissima (Mill.) Swingle.

The effect of temperature on carbon, nitrogen elements, and chlorophyll-a content in harmful algal blooms and their role in marine carbon and nitrogen cycles.

This study investigates the impact of temperature on the carbon, nitrogen elements, and chlorophyll-a content in harmful algal blooms, revealing their potential contribution to blue carbon ecosystems. By culturing 15 species of dinoflagellate at various temperatures, we measured their carbon, nitrogen, and chlorophyll-a content. The results indicated that temperature significantly influences the growth rate, C/N ratio, and chlorophyll-a content of these dinoflagellate.

Inhibition of FTO expression by thiodiphenol impairs Leydig cell maturation in pubertal male rats.

This study investigated the multifaceted effects of 4,4'-thiodiphenol (TDP) on male reproductive health, focusing on its toxicity, hormonal modulation, and impact on steroidogenesis. Male rats were exposed to TDP at varying doses (0, 1, 10, and 100 mg/kg) from day 35-56 postpartum. Overt toxicity was evident as TDP significantly reduced inhibited spermatogenesis at 10 and 100 mg/kg.

Pharmacokinetics and Biological Activities of Notoginsenoside R1: A Systematical Review.

(PN) root is a renowned nutritional supplement, health food additive, and traditional medicine that maintains homeostasis within the human microcirculatory system. Notoginsenoside R1 (NG-R1), an active compound derived from PN root, has been reported to possess various pharmacological activities, including anti-inflammatory, antioxidant, anticancer, antimicrobial, and angiogenic effects. However, NG-R1's pharmacokinetic properties and pharmacological activities have not been systematically elucidated.

[Effect and differentiation of spontaneous nystagmus of acute unilateral vestibulopathy on saccade in the video head impulse test].

Exploring the performance characteristics of spontaneous nystagmus（SN） in video-head impulse test（vHIT） and its possible effects on saccade. Vestibular function tests such as vHIT and SN were conducted in 48 patients with acute unilateral vestibulopathy（AUVP）. The saccade characteristics of vHIT in patients without SN and those with SN were analyzed, as well as the expression characteristics of SN in vHIT.

New Materials and Structures: Anti-Escape Trap Net for Trapping (Harold, 1880) (Coleoptera: Curculionidae).

The weevil (Harold, 1880), a wood-boring pest of (Mill.) Swingle, has caused significant ecological damage and economic loss in China. Physical control was effective against the related species (Motschulsky).

Knockdown of the long noncoding RNA VSIG2-1:1 promotes the angiogenic ability of human pulmonary microvascular endothelial cells by activating the VEGF/PI3K/AKT pathway.

Background: Abnormal pulmonary vascular development poses significant clinical challenges for infants with bronchopulmonary dysplasia (BPD). Although numerous factors have been suggested to control the development of pulmonary blood vessels, the mechanisms underlying the role of long noncoding RNAs (lncRNAs) in this process remain unclear.

Methods: A lncRNA array was used to measure the differential expression of lncRNAs in premature infants with and without BPD.

Insights of the peroxychloroformyl radical ClC(O)OO microwave spectrum.

The exploration of Venus has received much attention in the past and will keep growing due to the starting of the NASA DAVINCI project. To explain the extremely low O : CO ratio observed in Venus' atmosphere, a chlorine-initiated CO oxidation catalytic cycle has been proposed. However, relevant studies on the key intermediates, such as the peroxychloroformyl radical (ClC(O)OO), are rare.

MELAS Presenting as Bilateral Symmetric Occipital and Temporal Cortices Lesions: A Case Report and Literature Review.

Introduction: Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode (MELAS) is one of the most common maternally inherited mitochondrial diseases. The stroke-like episode affecting the cortical cortex is the hallmark of MELAS; however, it rarely presents as simultaneously bilateral symmetric cortices lesions.

Case Report: We reported a case of MELAS in a 46-year-old female patient with bilateral symmetric occipital and internal temporal cortices involvements on brain magnetic resonance imaging (MRI).

Physiology and Execution of Swallowing Maneuvers in 3D Videos: Integrating the Technology into Patient Care.

Educational technologies have proven to be an effective way to guide and educate patients, allowing them to increase awareness of their dysphagia condition and how treatment will help them. In this sense, this study aimed to develop and validate the content and appearance of 3D iconographic videos, which addressed the physiological demonstration and execution of protective and facilitating swallowing maneuvers, as well as verifying the feasibility of its use in teleconsultation, having adults and elderly people with oropharyngeal dysphagia as the main target audience. The development of the 3D videos was elaborated based on a guiding scientific script, constructed from an integrative literature review.

Does bumblebee preference of continuous over interrupted strings in string-pulling tasks indicate means-end comprehension?

Bumblebees () have been shown to engage in string-pulling behavior to access rewards. The objective of this study was to elucidate whether bumblebees display means-end comprehension in a string-pulling task. We presented bumblebees with two options: one where a string was connected to an artificial flower containing a reward and the other presenting an interrupted string.

Storage causes protein oxidation of soybean meal and affects antioxidant status, digestive performance and meat quality of broilers.

Objective: This study investigated the protein oxidation of soybean meal (SBM) stored in a warehouse and the effects of SBM on growth performance, antioxidant status, digestive performance, intestinal morphology, and breast muscle quality of broilers.

Methods: In total, 160 one-day-old Arbor Acres Plus broilers (half male and half female) were randomly divided into two groups with ten replicates of eight birds each: The control group was served with a basal diet including SBM stored at -20°C (FSBM), and the experimental group was served with a basal diet including SBM stored in a warehouse at room temperature for 45 days (RSBM).

Results: Compared with FSBM, the protein carbonyl level in RSBM was increased, the free and total thiol levels and in vitro digestibility of protein were decreased.

Subanesthetic Dose of Esketamine Improves the Sedative and Analgesic Effects of Dexmedetomidine and Remifentanil in Liposuction Anesthesia: A Prospective, Double-Blinded, Randomized Controlled Trial.

Purpose: Esketamine have anesthetic and analgesic properties. This study aimed to observe the enhancing effect of subanesthetic doses of esketamine (0.15-0.

Dietary supplementation with a silicate clay mineral (palygorskite) alleviates inflammatory responses and intestinal barrier damage in broiler chickens challenged with Escherichia coli.

This experiment aimed to explore the protective effects of dietary palygorskite (Pal) supplementation on inflammatory responses and intestinal barrier function of broiler chickens challenged with Escherichia coli (E. coli). A 2 × 2 factorial arrangement was designed to assess the effects of Pal administration (0 or 5 g/kg of feed) and E.

Bumblebees attend to both the properties of the string and the target in string-pulling tasks, but prioritize the features of the string.

Previous studies have demonstrated that associative learning and experience play important roles in the string-pulling of bumblebees (Bombus terrestris). However, the features of the target (artificial flower with sugar reward) and the string that bees learn in such tasks remain unknown. This study aimed to explore the specific aspects of the string-flower arrangement that bumblebees learn and how they prioritize these features.

A mechanics-based model for predicting flexible needle bending with large curvature in soft tissue.

Percutaneous insertion is one of the most common minimally invasive procedures. Compared with traditional straight rigid needles, bevel-tipped flexible needle can generate curved trajectories to avoid obstacles and sensitive organs. However, the nonlinear large deflection problem challenges the bending prediction of the needle, which dramatically influences the surgical success rate.

Chemical Kinetic Study of the Reaction of CHOO with CHO.

Criegee intermediates play an important role in the oxidizing capacity of the Earth's troposphere. Although extensive studies have been conducted on Criegee intermediates in the past decade, their kinetics with radical species remain underexplored. We investigated the kinetics of the simplest Criegee intermediate, CHOO, with the methyl peroxy radical, CHO, as a model system to explore the reactivities of Criegee intermediates with peroxy radicals.