Renewable, All-Natural Flute Membrane with Excellent Mechanical Properties for Osmotic Energy Harvesting.

Ion-selective membranes serve as key materials for reverse electrodialysis (RED) technology in osmotic energy harvesting, and the search for a class of membranes that are economical, highly robust, and sustainable has been a relentless goal for researchers. In this work, all-natural biomass membranes (reed membranes) are often used as a flute diaphragm, which makes the flute produce a brighter and crisper sound, presenting high strength and elasticity. Ultrathin natural reed membranes (thickness of ≈4.

Cocrystal@protein-anchoring nanococktail for combinatorially treating multidrug-resistant cancer.

Multidrug resistance (MDR), the major mechanism by which various cancers develop specific resistance to therapeutic agents, has set up enormous obstacles to many forms of tumor chemotherapy. Traditional cocktail therapy administration, based on the combination of multiple drugs for anti-MDR chemotherapy, often suffers from inconsistent pharmacokinetic behaviors that cannot act synchronously on the lesions, leading to limited pharmacodynamic outcomes. Despite the emergence of nanomedicines, which has improved chemotherapeutic drugs' bioavailability and therapeutic effect on clinical application, these monotherapy-based nano-formulations still show poor progression in overcoming MDR.

Spray-Coated Ultrathin and Porous Films for Physiological Sensing and Force Detection.

Epidermal electronics employed on human skin for the long term require good breathability and nonforeign wearing. In this work, we combine phase separation and spray coating to fabricate a porous and ultrathin electrode within minutes as well as micrometer-scale porous pressure sensors. The resulting electrodes show a water vapor transmission rate of 18.

Mechanically robust ultrathin nanofibrous films by using microfluidic-based continuous printing.

Ultrathin nanofibrous films with unique properties, such as controlled thickness, structures, and excellent mechanical robustness, play a vital role in flexible wearable devices, electronic skin, and rechargeable batteries. However, nanofibrous films are always facing limitations in their mechanical properties, even though they are strong when used as textiles, mainly owing to their structural shortcomings by using conventional fabrication methods. Herein, we present the fabrication of free-standing ultrathin nanofibrous films with good mechanical properties by using a microfluidic-based continuous printing strategy.

Intercropping changed the soil microbial community composition but no significant effect on alpha diversity.

Introduction: Enhancing the planning of the forest-agricultural composite model and increasing the efficiency with which forest land is utilized could benefit from a thorough understanding of the impacts of intercropping between forests and agriculture on soil physicochemical properties and microbial communities.

Methods: × cv. and intercrop soils, along with their corresponding monocrops, were used in this study's llumina high-throughput sequencing analysis to determine the composition and diversity of soil bacterial and fungal communities.

Durable anti-fog micro-nano structures fabricated by laser ablation of aluminum film on resin/glass.

This study presents a technique for processing transparent glass and resin substrates using a low-cost laser marker to create a micro-nano-structured surface with exceptional anti-fog properties. The approach involved depositing an aluminum (Al) film on the transparent substrates as an absorbing layer, followed by rapid laser marker ablation. This ablation process effectively removed the majority of the Al film, resulting in the formation of hierarchical hillock-hollow micro-structures and the dispersion of Al-based nano-particles throughout the surface.

Impacts of litter microbial community on litter decomposition in the absence of soil microorganisms.

Unlabelled: What is the effect of phyllosphere microorganisms on litter decomposition in the absence of colonization by soil microorganisms? Here, we simulated the litter standing decomposition stage in the field to study the differences in the composition and structure of the phyllosphere microbial community after the mixed decomposition of × and var. litter. After 15 months of mixed decomposition, we discovered that litters that were not in contact with soil had an antagonistic effect (the actual decomposition rate was 18.

Screening, Identification, and Fermentation Condition Optimization of a High-Yield 3-Methylthiopropanol Yeast and Its Aroma-Producing Characteristics.

A high-yield 3-methylthiopropanol (3-Met) yeast Y1402 was obtained from sesame-flavored Daqu, and it was identified as . Y1402 showed a broad range of growth temperatures and pH, as well as the maximum tolerance to glucose, NaCl, nicotine, and 3-Met at 50% (/), 15% (/), 1.2 g/L, and 18 g/L, respectively.

Superaerophilic/Superaerophobic NiFe-LDHs Electrode for Enhancing Overall Water Splitting in Alkaline Media.

Overall water splitting, as a critical approach to producing green hydrogen, is greatly impeded by the mass transfer of gaseous bubbles and dissolved gas molecules. Herein, a bifunctional superaerophilic/superaerophobic (SAL/SAB) NiFe layered-double-hydroxides (LDHs) electrode has been developed, which can drive H and O bubbles out of the reaction system by asymmetric Laplace pressure and accelerate dissolved gases diffusion through reducing their diffusion distance. Consequently, the SAL/SAB NiFe-LDHs electrode exhibits excellent HER activity with an overpotential of -76 mV at -10 mA cm and outstanding oxygen evolution reaction activity with an overpotential of 253 mV at 100 mA cm.

The Identification of a Strain for the Biological Purification of Soy Molasses to Produce Functional Soy Oligosaccharides and Optimize Purification Conditions.

Soy molasses is rich in oligosaccharides like sucrose, stachyose, and raffinose, with stachyose and raffinose being functional oligosaccharides. Harnessing soy molasses for the production of functional soy oligosaccharides (FSO) can significantly elevate its value. Biological purification, a method leveraging the selective utilization of different carbon sources by microorganisms, allows for the specific removal of sucrose from soy molasses while preserving stachyose and raffinose, thereby increasing the FSO content.

Insight into the fracture energy dissipation mechanism in elastomer composites sacrificial bonds and fillers.

Most tough elastomer composites are reinforced by introducing sacrificial structures and fillers. Understanding the contribution of fillers and sacrificial bonds in elastomer composites to the energy dissipation is critical for the design of high-toughness materials. However, the energy dissipation mechanism in elastomer composites remains elusive.

Co-delivery of indomethacin and uricase as a new strategy for inflammatory diseases associated with high uric acid.

Uric acid is the final metabolite in humans. High level of uric acid chronically induces urate deposition, aggravates kidney damage, and concomitantly causes an increase in inflammatory factors. Alleviating acute inflammation and decreasing uric acid levels are the key points in the treatment of inflammatory diseases associated with high uric acid.

Preparation and Improvement of Physicochemical and Functional Properties of Dietary Fiber from Corn Cob Fermented by .

Corn cobs were fermented with to produce soluble dietary fiber (SDF) of high quality and excellent food safety. In this work, the fermentation process was optimized by single-factor test and response surface methodology (RSM). The optimal fermentation conditions were determined to be a material-liquid ratio of 1:30, an inoculum concentration of 11%, a temperature of 32°C, a time of 6 days, and a shaking speed of 200 r/min.

High Strength MXene/PBONF Heterogeneous Membrane with Excellent Ion Selectivity for Efficient Osmotic Energy Conversion.

Layered MXene nanofluidic membranes still face the problems of low mechanical property, poor ion selectivity, and low output power density. In this work, we successfully constructed heterostructured membranes with the combination of the layered channels of the MXene layer on the top and the nanoscale poly(-phenylene-benzodioxazole) nanofiber (PBONF) layer on the bottom through a stepwise filtration method. The as-prepared MXene/PBONF-50 heterogeneous membrane exhibits high mechanical properties (strength of 221.

A Simplified Method for the Preparation of Highly Conductive and Flexible Silk Nanofibrils/MXene Membrane.

Silk nanofibers (SNF) have great applications in high-performance functional nanocomposites due to their excellent mechanical properties, biocompatibility, and degradability. However, the preparation of SNF by traditional methods often requires the use of some environmentally harmful or toxic reagents, limiting its application in green chemistry. In this paper, we successfully prepared SNF using natural silk as raw material and solvent stripping technology by adjusting the solvent concentration and solution ratio (the diameter of about 120 nm).

[Improvement and application on the estimation model of windbreak and sand fixation function based on remote sensing soil moisture factor].

Soil moisture factor is one of the important parameters in the study of wind and sand fixation functions of ecosystems. Traditional methods often use potential evaporation, rainfall, and irrigation observed by meteorological stations to estimate soil moisture, which has significant limitations in terms of spatial continuity and data availability. Based on the development of remote sensing technology in soil moisture detection, we selected four remote sen-sing indicators for soil moisture (MODIS evapotranspiration ratio method, SMAP soil moisture ratio method, visible shortwave infrared drought index method, and remote sensing humidity index method) to improve the estimation of soil moisture factor in the modified wind erosion equation model (RWEQ), and used the improved algorithm to analyze the spatiotemporal variations and driving factors of wind prevention and sand fixation services in the northwest region of Liaoning Province from 2001 to 2021.

Effect of Sonication and Ceria Doping on Nanoparticles Fabricated by Laser Marker Ablation of Ti in Water.

By employing the laser marker fast ablation technique in water, combined with the innovative inclusion of sonication, we successfully developed Ti-based nanoparticles with improved characteristics. sonication increased the nanoparticle concentration in the colloid, reduced nanoparticle size, and also narrowed size distribution. Our findings also provide valuable insights into the influence of laser parameters, such as wavelength and fluence, on nanoparticle properties.

Alleviating experimental pulmonary hypertension co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries.

Pulmonary hypertension (PH) is an insidious pulmonary vasculopathy with high mortality and morbidity and its underlying pathogenesis is still poorly delineated. The hyperproliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs) contributes to pulmonary vascular remodeling in pulmonary hypertension, which is closely linked to the downregulation of fork-head box transcriptional factor O1 (FoxO1) and apoptotic protein caspase 3 (Cas-3). Here, PA-targeted co-delivery of a FoxO1 stimulus (paclitaxel, PTX) and Cas-3 was exploited to alleviate monocrotaline-induced pulmonary hypertension.

Approved Nanomedicine against Diseases.

Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases. Nanotechnology represents one of the most effective approaches in elevating a drug's treatment efficacy and reducing toxicity by improving drug solubility, altering biodistribution, and controlling the release. The development of nanotechnology and materials has brought a profound revolution to medicine, significantly affecting the treatment of various major diseases such as cancer, injection, and cardiovascular diseases.

Study on the mechanism of Gualou Xiebai Guizhi decoction (GLXBGZD) in the treatment of coronary heart disease based on network pharmacology.

Background: This study aims to analyze the mechanism of Gualou Xiebai Guizhi decoction (GLXBGZD) in treating coronary heart disease (CHD) utilizing network pharmacology.

Methods: The GLXBGZD effective components were searched on the pharmacological database platform of the Traditional Chinese Medicine Systems Pharmacol, and its potential target was predicted. The Online Mendelian Inheritance obtained CHD disease target in Man and GeneCards database.

Superhydrophobic E-textile with an Ag-EGaIn Conductive Layer for Motion Detection and Electromagnetic Interference Shielding.

As as emerging innovation, electronic textiles have shown promising potential in health monitoring, energy harvesting, temperature regulation, and human-computer interactions. To access broader application scenarios, numerous e-textiles have been designed with a superhydrophobic surface to steer clear of interference from humidity or chemical decay. Nevertheless, even the cutting-edge electronic textiles (e-textiles) still have difficulty in realizing superior conductivity and satisfactory water repellency simultaneously.

The effects of protein corona on in vivo fate of nanocarriers.

With the emerging advances in utilizing nanocarriers for biomedical applications, a molecular-level understanding of the in vivo fate of nanocarriers is necessary. After administration into human fluids, nanocarriers can attract proteins onto their surfaces, forming an assembled adsorption layer called protein corona (PC). The formed PC can influence the physicochemical properties and subsequently determine nanocarriers' biological behaviors.

Exploring bioactive peptides as potential therapeutic and biotechnology treasures: A contemporary perspective.

In preceding years, bioactive peptides (BAPs) have piqued escalating attention owing to their multitudinous biological features. To date, many potential BAPs exhibiting anti-cancer activities have been documented; yet, obstacles such as their safety profiles and consumer acceptance continue to exist. Moreover, BAPs have been discovered to facilitate the suppression of Coronavirus Disease 2019 (CoVID-19) and maybe ideal for treating the CoVID-19 infection, as stated by published experimental findings, but their widespread knowledge is scarce.