Publications by authors named "Chao Peng"

Rationale: Antibiotic-associated hemorrhagic colitis (AAHC) is a special type of antibiotic-associated colitis. Due to the increased use of antibiotics, especially amoxicillin, which is commonly used in clinical practice, the incidence of antibiotic-associated hemorrhagic colitis has also increased. However, doctors have insufficient understanding of this disease, and patients may be missed or misdiagnosed.

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  • A multi-index nomogram prediction model was developed to assess clinically significant prostate cancer by integrating PI-RADS V2.1 scores, quantitative MRI parameters, and clinical factors in a study involving over 2000 patients.
  • The model's effectiveness was evaluated using various statistical methods, including AUC (Area Under the Curve), revealing high sensitivity and specificity, particularly with two models: one combining PI-RADS and PSAD, and another that added ADCmean.
  • Validation results indicated strong performance in predicting CSPCa across both internal and external cohorts, with no significant difference found between predicted and actual probabilities, supporting the model's reliability.
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The quality performance of power equipment suppliers is directly related to the stable and safe operation of the grid. This study presents a decision-making model based on q-rung orthopair fuzzy sets (q-ROFS) to evaluate suppliers, focusing on quality as the key criterion. To assess the objectivity and comprehensiveness of the results, we provide an innovative information fusion method that integrates the four dimensions of supply risk, supplier quality capability, profit impact, and willingness into the decision-making process.

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  • Flexible and wearable devices are proving useful for human-machine interactions (HMIs) and the Internet of Things, but there's a need for better communication storage and simpler designs.
  • A new approach inspired by natural tendons uses magnetized strings to detect vibrations; the strings' unique frequencies send signals through a single channel, allowing for multiple commands.
  • This method allows for customizable interactions by adjusting string tension, demonstrating potential use in areas like authentication, robotics, and other multifunctional applications.
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  • The study aims to explore how lncRNA SNHG12 influences the transition of macrophages to myofibroblasts in cancer-associated fibroblast-derived extracellular vesicles in non-small cell lung cancer (NSCLC).
  • Researchers isolated extracellular vesicles from NSCLC tissue and examined their composition, while also investigating the interactions among lncRNA SNHG12, miR-181a-5p, and Smad3.
  • The findings revealed that lncRNA SNHG12 promotes the transformation of M2 macrophages into myofibroblasts, significantly increasing Smad3 expression through its interaction with miR-181a-5p.
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Nanozymes, as promising alternatives to natural enzymes, offer several advantages with biocatalytic functions but remain inferior in catalytic activity. It is crucial to focus on factors that affect the enzymatic activity of nanozymes and develop strategies to make them more competitive with natural enzymes. Herein, CuVO nanorods are confirmed to own the intrinsic laccase-like activity, and an acetonitrile (MeCN)-mediated strategy is proposed for reaction acceleration by mimicking the enzymatic substrate pocket.

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A large number of joints and fissures are prevalent in the rock mass, which has an important influence on the mechanical properties of the rock mass. To study the failure mechanical characteristics of Y-cracked rocks, the paper analyzes the influence of different angles of prefabricated Y-cracked rocks on the mechanical strength characteristics of the rocks and the crack extension evolution through uniaxial compression indoor tests and discrete element PFC2D numerical simulation. The results indicate that the stress-strain curves of rocks containing prefabricated cracks exhibit five stages: the initial pore-fracture compaction stage, the elastic stage, the crack stable development stage, the crack unstable development stage, and the post-peak rupture.

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Trichloroethylene (TCE) contamination presents a significant environmental challenge, necessitating efficient treatment solutions. This study aimed to develop an optimized immobilized bioreactor using methanotrophs for TCE degradation. Activated carbon fibres were identified as the optimal immobilization material, with an adsorption rate of 6-23 h - significantly faster than over 50 h for other materials - and the highest methane oxidation capacity of 0.

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  • *This study focuses on the prognostic significance of ARHGAP9 in ccRCC, utilizing data from The Cancer Genome Atlas and protein analysis to compare expression levels in tumor versus normal tissues.
  • *Results show that higher ARHGAP9 expression correlates with advanced cancer stages, poorer patient survival, and significant associations with immune cell infiltration, suggesting its potential as a biomarker for ccRCC prognosis.
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  • The study focuses on the health impacts of heavy metals found in particulate matter (PM) in Kaifeng, China, particularly during winter, highlighting significant pollution levels of arsenic (As) and chromium (Cr).
  • Analysis revealed that while the overall non-carcinogenic health risk was low (HQ < 1), As and Cr presented substantial carcinogenic risks for both children and adults, necessitating serious concern.
  • The research identified industrial emissions and biomass combustion as major sources of these heavy metals, with industrial risks increasing significantly during the heating period, emphasizing the need for strategies to reduce air pollution and associated health risks.
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DYRK1A, a ubiquitously expressed kinase is linked to the dominant intellectual developmental disorder, microcephaly, and Down syndrome in humans. It regulates numerous cellular processes such as cell cycle, vesicle trafficking, and microtubule assembly. DYRK1A is a critical regulator of organ growth; however, how it regulates organ growth is not fully understood.

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  • A new deep learning model for detecting grape diseases uses multimodal data and unique activation functions to improve accuracy and robustness, achieving 91% accuracy and outperforming traditional models like YOLOv3 and YOLOv5.
  • The model demonstrated high performance metrics, including a precision of 93%, recall of 90%, and a speed of 56 frames per second.
  • A lightweight version was also created for mobile devices, utilizing techniques like structural pruning to ensure efficient real-time performance, marking a significant advancement in smart agriculture tools.
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The biogeochemical cycling of arsenic (As) is often intertwined with iron (Fe) and sulfur (S) cycles, wherein Fe(III)- and sulfate-reducing bacteria (SRB) play a crucial role. Here, we isolated strain DS-1, a strictly anaerobic Fe(III)- and sulfate-reducing bacterium, from As-contaminated paddy soil. Using 16S rRNA gene sequence analysis, strain DS-1 was identified as a member of the genus Desulfovibrio.

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Aqueous zinc-bromine (Zn||Br) batteries are regarded as one of the most promising energy storage devices due to their high safety, theoretical energy density, and low cost. However, the sluggish bromine redox kinetics and the formation of a soluble tribromide (Br ) hinder their practical applications. Here, it is proposed dispersed single iron atom coordinated with nitrogen atoms (FeN) in a mesoporous carbon framework (FeSAC-CMK) as a conductive catalytic bromine host, which possesses porous structure and electrocatalytic functionality of FeN species for enhanced confinement and electrocatalytic effect.

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Objective: This prospective observational study aims to demonstrate the clinical efficacy of dienogest in treating endometriomas with a maximum diameter of ≥4 cm.

Methods: Patients ( = 81) with endometriomas (diameter of ≥4 cm) were enrolled and administered orally with dienogest (2 mg daily) and followed up for a year [Ethical approval code: 2020 Research 343]. Further, the efficacy was determined by recording the largest diameter and volume of the endometriomas, uterine volume, endometrial thickness, and the largest diameter of uterine fibroids in the patients during 0, 6, and 12 months.

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Heterotopic ossification (HO), often arising in response to traumatic challenges, results from the aberrant osteochondral differentiation of mesenchymal stem cells (MSCs). Nevertheless, the impact of trauma-induced inflammatory exposure on MSC fate determination remains ambiguous. In this study, the cellular diversity within inflammatory lesions is elucidated, comprising MSCs and several innate and adaptive immune cells.

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Based on current challenges of poor targeting and limited choices in chemical control methods of cyanobacterial blooms (CBs), identifying new targets is an urgent and formidable task in the quest for target-based algaecides. This study discovered -acylamino saccharin derivatives exhibiting potent algicidal activity. Thus, using -acylamino saccharin as the probes, glyceraldehyde-3-phosphate dehydrogenase from cyanobacterial (GAPDH) was identified as a new target of algaecides through the activity-based protein profiling (ABPP) strategy for the first time.

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Aims: Rhodotorula mucilaginosa (Rho) can develop a range of strategies to resist the toxicity of heavy metals. This study aimed to investigate the physiological responses and transcriptomic regulation of the fungus under different heavy metal stresses.

Methods And Results: This study applied transmission electron microscopy and RNA-seq to investigate the fungal resistance to Pb, Cd, and Cu stresses.

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  • This paper presents a new deep learning model that combines Diffusion-Transformer architecture and a parallel attention mechanism to improve growth estimation and disease detection in jujube forests.
  • The model addresses shortcomings of existing methods in large and complex forest monitoring by enhancing data processing and feature extraction capabilities.
  • Experimental results show significant performance improvements—95% precision, 92% recall, 93% accuracy, and 94% F1-score—compared to traditional and common deep learning models, also validating the effectiveness of its unique attention mechanisms.
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  • BCOR-PRC1.1 recruitment to non-methylated CpG islands via KDM2B is crucial for controlling transcription during development and cancer, but the regulatory mechanisms are still not fully understood.
  • Research highlights the significance of negatively charged Poly-D/E regions in BCOR for binding to KDM2B and how these regions inhibit liquid-liquid phase separation (LLPS) for BCOR/PCGF1.
  • The study suggests that neutralizing the negative charges with calcium (Ca) alters the interaction between BCOR/PCGF1 and KDM2B, promoting the formation of liquid-like droplets and enhancing the recruitment of the BCOR-PRC1.1 core to KDM2B target sites.
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Bladder cancer (BC) is a prevalent type of tumor in the urinary system, and it has been discovered that long non-coding RNA (lncRNA) plays a significant role in its occurrence and development. However, thus far, no reports have been published on the involvement of LINC00461 in BC. Here, we found that LINC00461 levels were upregulated in BC tissues and cell lines.

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Objective: To observe the clinical effect of electrophysiological technique in treating chronic prostatitis.

Methods: Choose 40 patients of chronic prostatitis/chronic pelvic pain syndrome (chronicprostatis/chronicpelvicpainsyndrome, CP/CPPS) in People's Hospital in Zhijin and People's hospital in Guizhou Province from January 2022 to April 2023, The patients were randomly divided into control group (n=20) and treatment group (n=20). The treatment group received low-frequency neuromuscular electrical stimulation combined with drug therapy, while the control group received drug therapy alone.

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  • TFEB is a key factor in the regulation of lysosomes and autophagy, and its activity can be modified post-translationally.
  • Lactate can chemically modify TFEB through a process called lactylation, which stabilizes TFEB by preventing its degradation.
  • Increased levels of lactylated TFEB were found in pancreatic cancer samples, suggesting that lactylation may enhance autophagy in rapidly growing cancer cells.
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Regulating cardiolipin to maintain mitochondrial homeostasis is a promising strategy for addressing Parkinson's disease (PD). Through a comprehensive screening and validation process involving multiple models, ginsenoside Rg3 (Rg3) as a compound capable of enhancing cardiolipin levels is identified. This augmentation in cardiolipin levels fosters mitochondrial homeostasis by bolstering mitochondrial unfolded protein response, promoting mitophagy, and enhancing mitochondrial oxidative phosphorylation.

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