Publications by authors named "Chao Mo"

Background: Diabetic kidney disease (DKD) is the primary contributor to renal failure and poses a severe threat to human health. Accumulating studies demonstrated that competing endogenous RNA (ceRNA) network is involved in cuproptosis and DKD progression. However, the role of cuproptosis-associated ceRNA network and immune infiltration in DKD remains largely unclear.

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Antibiotics are emerging organic pollutants that have attracted huge attention owing to their abundant use and associated ecological threats. The aim of this study is to develop and use photocatalysts to degrade antibiotics, including tetracycline (TC), ciprofloxacin (CIP), and amoxicillin (AMOX). Therefore, a novel Z-scheme heterojunction composite of g-CN (gCN) and 3D flower-like BiWO (BW) perovskite structure was designed and developed, namely BiWO/g-CN (BW/gCN), which can degrade low-concentration of antibiotics in aquatic environments under visible light.

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As a high-performance engineering plastic, polyarylene ether nitrile (PEN) is widely used in many fields. The presence of cyano groups of PEN ensures its good adhesion to other substrates, but the inherent low crystallinity of PEN limits its application. In this work, the poly(aryl ether ketone) segment was introduced into PEN via copolymerization using both 2,6-Dichlorobenzonitrile and 4,4'-Difluorobenzophenone as the starting reagents to prepare poly (ether nitrile ketone) (BP-PENK).

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Article Synopsis
  • - The study explores the efficacy of Compound Xiancao Granule (CXCG), a traditional Zhuang remedy, in treating diabetic kidney disease (DKD) and aims to uncover its underlying mechanisms using multi-omics approaches.
  • - CXCG was found to contain 118 compounds and demonstrated improvements in glucose metabolism, renal function, and inflammation in diabetic rats, while also restoring gut microbiota balance.
  • - The research utilized various analytical techniques, revealing that CXCG influences DKD mainly by modulating inflammatory responses and metabolic processes related to carbohydrates and amino acids.
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Article Synopsis
  • Exosomes are tiny vesicles that facilitate communication between cells and are significant in both healthy and disease states.
  • Traditional Chinese Medicine (TCM) has been used for maintaining health and treating diseases, and recently, research has focused on how TCM interacts with exosomes.
  • TCM formulas can modulate exosomes to help treat various disorders like tumors and kidney diseases by reducing cell growth, inflammation, and oxidative stress, and they may also serve as indicators for TCM syndromes.
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Background: Bailing Capsule (BLC), Jinshuibao (JSB), Huangkui Capsule (HKC), Uremic Clearance Granule (UCG), Tripterygium glycosides (TG), Compound Xueshuantong Capsule (CXC), and Shenyan Kangfu Tablet (SYKFT) as classic Chinese patent medicines (CPMs), have been widely used and shown beneficial effects on the treatment of early diabetic kidney disease (DKD). However, the comparative efficacy of seven CPMs in the treatment of early DKD remains unknown.

Objective: To evaluate and compare the efficacy of seven CPMs (BLC, JSB, HKC, UCG, TG, CXC, SYKFT) combined with angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) on early DKD by a Bayesian network meta-analysis (NMA) of randomized controlled trials (RCTs).

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Background: Curcumin, a polyphenolic constituent from , possesses antioxidant, hypolipidemic, and antidiabetic properties and has been reported to protect against diabetic kidney disease (DKD); however, the effect is inconsistent.

Objective: This systematic review and meta-analysis aimed to investigate the effect of curcumin supplementation on renal function, lipid profile, blood pressure, and glycemic control in DKD.

Methods: A systematic and comprehensive literature search of interrelated randomized controlled trials (RCTs) was conducted in PubMed, Embase, Cochrane Library, Web of Science, Scopus, and ClinicalTrials.

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Background: (AR)- (PN), a classical herb pair, has shown significant effects in treating diabetic nephropathy (DN). However, the intrinsic mechanism of treating DN is still unclear. This study aims to illustrate the mechanism and molecular targets of - treating DN based on network pharmacology combined with bioinformatics.

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The diversity and community composition of archaea in soil samples from three wetlands (SP1, SP2, and SP3) of Ebinur Lake were studied by constructing 16S rDNA cloning library. The correlation between the diversity of archaea and soil environmental factors was analyzed by CANOCO software. The aim of this study was to reveal the differences of community structures of archaea in different sample sites, to provide a theoretical basis for further study on degradation and restoration of Ebinur Lake wetland.

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Buyang Huanwu Decoction(BHD) has the effect in benefiting Qi and activating blood circulation,and is the representative prescription for benefiting Qi and activating blood. At present,it is used for treatment of early diabetic nephropathy. However,its efficacy and safety remained to be verified.

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Objective: In order to study the community diversity of rhizosphere soil ammonia-oxidizing bacteria, Halocnemum strobilaceum, Reed and Salicornia in Ebinur Lake Wetland were investigated.

Methods: The clone libraries of amoA gene were constructed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), and phylogenetics were analyzed. To explore the community structure of rhizosphere amomonia-oxidizing bacteria, we combined rhizosphere physicochemical factors of the three plants.

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