Background: Diabetic kidney disease (DKD) is the primary contributor to renal failure and poses a severe threat to human health. Accumulating studies demonstrated that competing endogenous RNA (ceRNA) network is involved in cuproptosis and DKD progression. However, the role of cuproptosis-associated ceRNA network and immune infiltration in DKD remains largely unclear.
View Article and Find Full Text PDFAntibiotics are emerging organic pollutants that have attracted huge attention owing to their abundant use and associated ecological threats. The aim of this study is to develop and use photocatalysts to degrade antibiotics, including tetracycline (TC), ciprofloxacin (CIP), and amoxicillin (AMOX). Therefore, a novel Z-scheme heterojunction composite of g-CN (gCN) and 3D flower-like BiWO (BW) perovskite structure was designed and developed, namely BiWO/g-CN (BW/gCN), which can degrade low-concentration of antibiotics in aquatic environments under visible light.
View Article and Find Full Text PDFPolymers (Basel)
January 2024
As a high-performance engineering plastic, polyarylene ether nitrile (PEN) is widely used in many fields. The presence of cyano groups of PEN ensures its good adhesion to other substrates, but the inherent low crystallinity of PEN limits its application. In this work, the poly(aryl ether ketone) segment was introduced into PEN via copolymerization using both 2,6-Dichlorobenzonitrile and 4,4'-Difluorobenzophenone as the starting reagents to prepare poly (ether nitrile ketone) (BP-PENK).
View Article and Find Full Text PDFBackground: Bailing Capsule (BLC), Jinshuibao (JSB), Huangkui Capsule (HKC), Uremic Clearance Granule (UCG), Tripterygium glycosides (TG), Compound Xueshuantong Capsule (CXC), and Shenyan Kangfu Tablet (SYKFT) as classic Chinese patent medicines (CPMs), have been widely used and shown beneficial effects on the treatment of early diabetic kidney disease (DKD). However, the comparative efficacy of seven CPMs in the treatment of early DKD remains unknown.
Objective: To evaluate and compare the efficacy of seven CPMs (BLC, JSB, HKC, UCG, TG, CXC, SYKFT) combined with angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) on early DKD by a Bayesian network meta-analysis (NMA) of randomized controlled trials (RCTs).
Evid Based Complement Alternat Med
December 2021
Background: Curcumin, a polyphenolic constituent from , possesses antioxidant, hypolipidemic, and antidiabetic properties and has been reported to protect against diabetic kidney disease (DKD); however, the effect is inconsistent.
Objective: This systematic review and meta-analysis aimed to investigate the effect of curcumin supplementation on renal function, lipid profile, blood pressure, and glycemic control in DKD.
Methods: A systematic and comprehensive literature search of interrelated randomized controlled trials (RCTs) was conducted in PubMed, Embase, Cochrane Library, Web of Science, Scopus, and ClinicalTrials.
Evid Based Complement Alternat Med
July 2021
Background: (AR)- (PN), a classical herb pair, has shown significant effects in treating diabetic nephropathy (DN). However, the intrinsic mechanism of treating DN is still unclear. This study aims to illustrate the mechanism and molecular targets of - treating DN based on network pharmacology combined with bioinformatics.
View Article and Find Full Text PDFThe diversity and community composition of archaea in soil samples from three wetlands (SP1, SP2, and SP3) of Ebinur Lake were studied by constructing 16S rDNA cloning library. The correlation between the diversity of archaea and soil environmental factors was analyzed by CANOCO software. The aim of this study was to reveal the differences of community structures of archaea in different sample sites, to provide a theoretical basis for further study on degradation and restoration of Ebinur Lake wetland.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
April 2019
Buyang Huanwu Decoction(BHD) has the effect in benefiting Qi and activating blood circulation,and is the representative prescription for benefiting Qi and activating blood. At present,it is used for treatment of early diabetic nephropathy. However,its efficacy and safety remained to be verified.
View Article and Find Full Text PDFWei Sheng Wu Xue Bao
September 2015
Objective: In order to study the community diversity of rhizosphere soil ammonia-oxidizing bacteria, Halocnemum strobilaceum, Reed and Salicornia in Ebinur Lake Wetland were investigated.
Methods: The clone libraries of amoA gene were constructed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), and phylogenetics were analyzed. To explore the community structure of rhizosphere amomonia-oxidizing bacteria, we combined rhizosphere physicochemical factors of the three plants.