Publications by authors named "Chao Feng"

The combination of reversible angular dispersion-induced microbunching (ADM) and the rapid damping storage ring provides a storage-ring-based light source with the capability to produce longitudinal coherent radiation with a high repetition rate. This paper presents a prototype design for a test facility based on the study by Jiang et al. [Sci.

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Macrophages that acquire an immunosuppressive phenotype play a crucial role in establishing the pre-metastatic niche (PMN), which is essential for facilitating breast cancer metastasis to distant organs. Our study showed that increased activity of the aryl hydrocarbon receptor (AHR) in lung macrophages plays a crucial role in establishing the immunosuppressive PMN in breast cancer. Specifically, AHR activation led to high expression of PD-L1 on macrophages by directly binding to the promoter of Pdl1.

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Exposure to perfluorooctane sulfonate (PFOS) has been associated with lower bone density and the occurrence of osteoporosis in human studies, but the effects and mechanisms of PFOS induces bone loss is not well understood. Our research is aimed at examining the effects of PFOS on osteoblastic activity and investigating the toxicological mechanisms of PFOS-induced bone loss. Cell proliferation, ALP activity, bone nodule formation, ROS levels, and cell apoptosis were assessed after treating osteoblasts with different concentrations of PFOS.

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Plants have unique adaptability to heavy metal pollution. However, the adaptation strategies of bryophytes are still unclear. In order to better understand the response of bryophytes to different heavy metal and the adaptation mechanisms of different species to heavy metal pollution, we studied soil physicochemical properties, distribution of heavy metal elements, ecological risk assessment and the community structure, functional characteristics of bryophytes in large open-pit coal mines in Inner Mongolia.

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Diatoms have developed unique micro- and nanostructures and photonic crystal properties during billions of years of life evolution. In this study, a fluorescence sensor substrate (QD-Diatom) was prepared by biofabrication, and CdSe/ZnS quantum dots (QDs) were immobilized on the surface of diatom biosilica. The concentration of CdSe/ZnS QDs of 7.

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Exciplex organic light-emitting diodes (OLEDs) are widely utilized for their high internal quantum efficiency. Although solution-processed devices offer the advantages of simple operation and low cost, few studies have reported on the preparation of exciplex OLED devices using solution methods. This paper presents exciplex OLEDs produced between m-MTDATA and Bphen, fabricated using a solution method and optimized by a polar solvent vapor annealing (PSVA) treatment.

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Stroke, an abrupt cerebrovascular ailment resulting in brain tissue damage, has prompted the adoption of motor imagery (MI)-based brain-computer interface (BCI) systems in stroke rehabilitation. However, analyzing electroencephalogram (EEG) signals from stroke patients poses challenges. To address the issues of low accuracy and efficiency in EEG classification, particularly involving MI, the study proposes a residual graph convolutional network (M-ResGCN) framework based on the modified -transform (MST), and introduces the self-attention mechanism into residual graph convolutional network (ResGCN).

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Electroencephalogram (EEG) signals exhibit multi-domain features, and electrode distributions follow non-Euclidean topology. To fully resolve the EEG signals, this study proposes a Temporal-Frequency-Spatial multi-domain feature fusion Graph Attention Network (TFSGAT) for motor imagery (MI) intention recognition in spinal cord injury (SCI) patients. The proposed model uses phase-locked value (PLV) to extract spatial phase connectivity information between EEG channels and continuous wavelet transform to extract valid EEG information in the time-frequency domain.

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Spinal cord injury (SCI), which is the injury of the spinal cord site resulting in motor dysfunction, has prompted the use of motor imagery (MI)-based brain computer interface (BCI) systems for motor function reconstruction. However, analyzing electroencephalogram signals and brain function mechanisms for SCI patients is challenging. This is due to their low signal-to-noise ratio and high variability.

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Although the nonmonotonic variation in the diffusion coefficients of alcohol and water with changing alcohol concentrations in aqueous solutions has been reported for many years, the underlying physical mechanisms remain unclear. Using molecular dynamics simulations, we investigated the molecular diffusion mechanisms in aqueous methanol solutions. Our findings reveal that the molecular diffusion is co-influenced by hydrogen bonding and the hydrophobic ends of methanol molecules.

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Squid, as a very important economic marine species, accounts for 5 % of the total catch of fish and cephalopods. The waste from the processing process of squid can be used for collagen extraction, which has great application value in the field of biomedical materials. Here, we obtained squid cartilage gelatin (SCG) with different molecular weights by adjusti.

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Purpose: This study aimed to report a newly developed, high-fidelity synthetic simulator to simulate excision and primary anastomotic (EPA) bulbar urethroplasty and its clinical use for new practitioners in shortening the learning curve.

Material And Methods: The bulbar urethral anastomosis simulator consists of several standardized components created according to the actual size of the male patient. Interns, novice residents, and fellows inexperienced with urethral reconstruction ( = 10, 5, 5) from different medical centres were invited to participate in the training programme.

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A novel citric acid (CA) modulation strategy was developed to prepare strong magnetic CoFe-LDH/CoFeO-C composites, which were combined with dielectric barrier discharge (DBD) to effectively degrade levofloxacin (LEV) in wastewater. Kelvin probe force microscopy (KPFM) test showed that CA modulation facilitated a more powerful internal electric field to drive rapid charge migration. The addition of CoFe-LDH/CoFeO-C increased LEV degradation from 78.

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Article Synopsis
  • Muscle stem cells (MuSCs) show promise in treating diseases with overactive immune responses, like colitis and lung injury, due to their ability to modulate the immune system.
  • In laboratory studies, MuSCs significantly inhibited T cell activation when exposed to inflammatory signals, and they helped reduce liver injury in mice through immunosuppressive mechanisms.
  • Key differences were found between mouse and human MuSCs: mouse MuSCs require inducible nitric oxide synthase (iNOS) for their immunosuppressive action, while human MuSCs rely on indoleamine 2,3-dioxygenase (IDO), indicating that species-specific factors are critical in evaluating MuSCs for immune-related therapies.
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Article Synopsis
  • Muscle invasive bladder cancer (MIBC) is a serious condition associated with high rates of metastasis and limited treatment options, where immune checkpoint inhibitors (ICIs) show potential as a new therapy.
  • A detailed analysis of tumor samples identified specific cancer stem cell-like populations, particularly those expressing IGF2BP3, which are linked to immune suppression and poorer survival outcomes in MIBC patients.
  • Research on IGF2BP3 revealed its significant role in regulating key genes and pathways, suggesting that targeting this gene could be vital for developing more effective immunotherapy strategies against MIBC.
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The recruitment of the protein spleen tyrosine kinase (Syk) to membrane-bound immune receptors is an essential step in initiating an immune response mediated through the activated receptors. Syk recognizes intracellular phosphorylated regions of membrane receptors known as immunoreceptor tyrosine-based activation motifs (ITAMs) defined by a sequence with two tyrosine (Y) amino acids separated by a certain spacing of six to eight residues: YXX(I/L)XYXX(I/L). Syk with doubly phosphorylated ITAM is high-affinity and negatively regulated when Syk itself becomes phosphorylated.

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Introduction: This study aimed to compare the clinical efficacy of sexual stimulation with that of placebo in the treatment of distal ureteral stones.

Methods: We searched PubMed, Web of Science, Cochrane Library, and Google Scholar from January 1, 2000 to December 31, 2022 for studies comparing the efficacy of sexual stimulus with that of placebo for the treatment of distal ureteral stones. RevMan 5.

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In immunology, the role of macrophages extends far beyond their traditional classification as mere phagocytes; they emerge as pivotal architects of the immune response, with their function being significantly influenced by multidimensional environmental stimuli. This review investigates the nuanced mechanisms by which diverse external signals ranging from chemical cues to physical stress orchestrate macrophage polarization, a process that is crucial for the modulation of immune responses. By transitioning between pro-inflammatory (M1) and anti-inflammatory (M2) states, macrophages exhibit remarkable plasticity, enabling them to adapt to and influence their surroundings effectively.

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Amides are an important type of synthetic intermediate used in the chemical, agrochemical, pharmaceutical, and nutraceutical industries. The traditional chemical process of converting nitriles into the corresponding amides is feasible but is restricted because of the harsh conditions required. In recent decades, nitrile hydratase (NHase, EC 4.

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Azoospermia is a significant reproductive challenge. Differentiating between non-obstructive azoospermia (NOA) and obstructive azoospermia (OA) is crucial as each type requires distinct management strategies. Testicular microcirculation plays a profound role in spermatogenic functions.

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Nonlinear-optical (NLO) crystals capable of controlling and manipulating light to generate coherent radiation at challenging wavelengths are of significant interest. However, designing a new UV NLO crystal remains difficult due to the rigid requirements for structure and properties. Herein, we have successfully designed and synthesized a novel noncentrosymmetric (NCS) rare-earth borate UV NLO crystal, KY(BO), through the heterovalence substitution of YAl(BO).

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Chitosan is a polymeric polysaccharide with widely application. At present, commercialized chitosan obtained by deacetylating chitin with acid-alkali method. The homogeneity of the molecular weight of chitosan is difficult to adjust due to the low homogeneity of chitosan itself and the degradation effect of the extraction process.

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Background: Skin aging is characterized by an imbalance between the generation and degradation of extracellular matrix molecules (ECM). Matrix metalloproteinases (MMPs) are the primary enzymes responsible for ECM breakdown. Intrinsic and extrinsic stimuli can induce different MMPs.

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Facilitating the surface reconstruction of pre-catalysts has been considered an effective strategy for constructing low-cost and highly efficient OER electrocatalysts. Metal doping is a feasible way to activate the surface reconstruction, thus enhancing the OER performance. Herein, we report a facile hydrothermal method to synthesize a series of Zn-doped Ni-MOF on nickel foam (NiZn-MOF/NF) as promising pre-catalysts toward the oxygen evolution reaction (OER).

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Structural regulation of Pd-based electrocatalytic hydrodechlorination (EHDC) catalyst for constructing high-efficient cathode materials with low noble metal content and high atom utilization is crucial but still challenging. Herein, a support electron inductive effect of Pd-Mn/Ni foam catalyst was proposed via in-situ Mn doping to optimize the electronic structure of the Ni foam (NF), which can inductive regulation of Pd for improving the EHDC performance. The mass activity and current efficiency of Pd-Mn/NF catalyst are 2.

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