Gustative Roussy Immune Score is a Predictor for Major Pathological Response in Rectal Cancer: A Result from the Preoperative Intraarterial Chemoembolization Combined with Radiotherapy (PCAR) Study.

Despite the emergence of various treatment strategies for rectal cancer based on neoadjuvant chemoradiotherapy, there is currently a lack of reliable biomarkers to determine which patients will respond well to neoadjuvant chemoradiotherapy. Through collecting hematological and biochemical parameters data of patients prior to receiving neoadjuvant chemoradiotherapy, we evaluated the predictive value of systemic inflammatory indices for pathological response and prognosis in rectal cancer patients. We found that baseline GRIm-Score was an independent predictor for MPR in rectal cancer patients.

Individual treatment strategy of thyroglossal duct cyst carcinoma: a case report.

Background: Neoplasia of ectopic thyroid components is relatively rare in thyroglossal duct cysts. We report a case of histopathologically confirmed papillary thyroid carcinoma in a thyroglossal duct cyst, discuss its clinical characteristics of, and provide reference for diagnosis and treatment.

Case Description: We presented a 25-year-old female went to hospital because of "a tumor in her neck".

Phase Conversion Accelerating "Zn-Escape" Effect in ZnSe-CFs Heterostructure for High Performance Sodium-Ion Half/Full Batteries.

Sodium-ion batteries (SIBs) are considered as a promising large-scale energy storage system owing to the abundant and low-cost sodium resources. However, their practical application still needs to overcome some problems like slow redox kinetics and poor capacity retention rate. Here, a high-performance ZnSe/carbon fibers (ZnSe-CFs) anode is demonstrated with high electrons/Na transport efficiency for sodium-ion half/full batteries by engineering ZnSe/C heterostructure.

Ultrafast and stable phase transition realized in MoTe-based memristive devices.

Phase engineering of two-dimensional transition metal dichalcogenides has received increasing attention in recent years due to its atomically thin nature and polymorphism. Here, we first realize an electric-field-induced controllable phase transition between semiconducting 2H and metallic 1T' phases in MoTe memristive devices. The device performs stable bipolar resistive switching with a cycling endurance of over 10, an excellent retention characteristic of over 10 s at an elevated temperature of 85 °C and an ultrafast switching of ∼5 ns for SET and ∼10 ns for RESET.

Size effect of bifunctional gold in hierarchical titanium oxide-gold-cadmium sulfide with slow photon effect for unprecedented visible-light hydrogen production.

Gold nanoparticles (Au NPs) with surface plasmonic resonance (SPR) effect and excellent internal electron transfer ability have widely been combined with semiconductors for photocatalysis. However, the in-depth effects of Au NPs in multicomponent photocatalysts have not been completely understood. Herein, ternary titanium oxide-gold-cadmium sulfide (TiO-Au-CdS, TAC) photocatalysts, based on hierarchical TiO inverse opal photonic crystal structure with different Au NPs sizes have been designed to reveal the SPR effect and internal electron transfer of Au NPs in the presence of slow photon effect.

Establishment and Verification of UPLC-MS/MS Technique for Pharmacokinetic Drug-Drug Interactions of Selinexor with Posaconazole in Rats.

Background: A method for the determination of selinexor by UPLC-MS/MS was established to study the effect of posaconazole on the pharmacokinetics of selinexor in rats.

Methods: The experiment rats were divided into group A (0.5% CMC-Na) and group B (posaconazole, 20 mg/kg), 6 rats in each group.

Coproduction of hydrogen and lactic acid from glucose photocatalysis on band-engineered ZnCdS homojunction.

Photocatalytic transformation of biomass into value-added chemicals coupled with co-production of hydrogen provides an explicit route to trap sunlight into the chemical bonds. Here, we demonstrate a rational design of ZnCdS solid solution homojunction photocatalyst with a pseudo-periodic cubic zinc blende (ZB) and hexagonal wurtzite (WZ) structure for efficient glucose conversion to simultaneously produce hydrogen and lactic acid. The optimized ZnCdS catalyst consists of a twinning superlattice, has a tuned bandgap, and displays excellent efficiency with respect to hydrogen generation (690 ± 27.

n-p Heterojunction of TiO-NiO core-shell structure for efficient hydrogen generation and lignin photoreforming.

Hydrogen evolution from biomass photoreforming has been widely recognized as a promising strategy for relieving the pressure from energy crisis and environmental pollution, as it could generate sustainable H and value-added bioproducts simultaneously. Combining p-type semiconductors with n-type semiconductors to form n-p heterojunction is an effective strategy to improve the photocatalytic quantum efficiency by enhancing the separation of photogenerated electrons and holes, which could greatly facilitate the realization of such biomass photorefinery concept. However, the incompact contact between the n-type and p-type semiconductors often induces the aggregation of photogenerated electrons and holes.

Aptamer-T Cell Targeted Therapy for Tumor Treatment Using Sugar Metabolism and Click Chemistry.

The development of a tumor-targeted immunotherapy is highly required. The most advanced application is the use of CD19 chimeric antigen receptor (CAR)T (CAR-T) cells to B cell malignancies, but there are still side effects including potential carcinogenicity of lentiviral or retroviral insertion into the host cell genome. Here, we developed a nonviral aptamer-T cell targeted strategy for tumor therapy.

Properties of a Novel Animal Model of LPR.

Background: Few satisfactory animal models of laryngopharyngeal reflux (LPR) is available. Interleukin-8 (IL-8) and vascular endothelial growth factor (VEGF) may be associated with the pathogenesis of LPR injuries and laryngeal carcinomas.

Objectives: To establish an animal model of LPR and to explore the related pathological changes and cytokine expression in the vocal cord tissue.

In-Situ Growing Mesoporous CuO/O-Doped g-CN Nanospheres for Highly Enhanced Lithium Storage.

The development of lithium-ion batteries using transition metal oxides has recently become more attractive, due to their higher specific capacities, better rate capability, and high energy densities. Herein, the in situ growth of advanced mesoporous CuO/O-doped g-CN nanospheres is carried out in a two step hydrothermal process at 180 °C and annealing in air at 300 °C. When used as an anode material, the CuO/O-doped g-CN nanospheres achieve a high reversible discharge specific capacity of 738 mAhg and a capacity retention of ∼75.

Molybdenum disulfide quantum dots directing zinc indium sulfide heterostructures for enhanced visible light hydrogen production.

Photocatalytic hydrogen (H) production based on semiconductors is important to utilize solar light for clean energy and environment. Herein, we report a visible light responsive heterostructure, designed and constructed by molybdenum disulfide quantum dots (MoS-QDs) in-situ seeds-directing growth and self-assemble of zinc indium sulfide (ZnInS) nanosheet to ensure their full contact through a simple one-step solvothermal method for highly improved visible light H production. The MoS-QDs in-situ seeds-directing ZnInS heterostructure not only builds heterojunctions between MoS and ZnInS to spatially separate the photogenerated electrons and holes, but also serves as the active sites trapping photogenerated electrons to facilitate H evolution.

MOF-derived nitrogen-doped core-shell hierarchical porous carbon confining selenium for advanced lithium-selenium batteries.

The lithium-selenium (Li-Se) battery has attracted growing interest recently due to its high energy density and theoretical capacity. However, the shuttle effect and volume change during cycling severely hinder its further application. In this work, we report a metal-organic framework (MOF)-derived nitrogen-doped core-shell hierarchical porous carbon (N-CSHPC) with interconnected meso/micropores to effectively confine Se for high-performance Li-Se batteries.

Cascade electronic band structured zinc oxide/bismuth vanadate/three-dimensional ordered macroporous titanium dioxide ternary nanocomposites for enhanced visible light photocatalysis.

Ternary zinc oxide/bismuth vanadate/three-dimensional ordered macroporous titanium dioxide (ZnO/BiVO/3DOM TiO) heterojuncted nanocomposites with cascade electronic band structures were successfully designed and synthesized for visible light photodegradation of two different molecules: Rhodamine B (RhB) and Tartrazine. The photocatalytic active species have been investigated by using electron scavenger (AgNO) and hole scavenger (Triethanolamine: TEOA). The band edge positions of each component in tenary nanocomposites have been measured by using photoelectrochemical Mott-Schottky method and valence band XPS (VB-XPS) spectroscopy.

Type II heterojunction in hierarchically porous zinc oxide/graphitic carbon nitride microspheres promoting photocatalytic activity.

Graphitic carbon nitride (g-CN) is a visible light active semiconductor. However, low conductivity and high recombination rate of photogenerated electrons and holes limit its application in photocatalysis. In this work, we design and synthesize hierarchically porous zinc oxide/graphitic carbon nitride (ZnO/g-CN) microspheres with type-II heterojunction to effectively degrade rhodamine B (RhB) via increasing the charge-separation efficiency.

[Spatial variation of soil carbon and stable isotopes in the southern margin desert of Junggar Basin, China].

The southern margin desert of Junggar Basin in the central arid region of Asia was selec-ted as the study area. To gain insight into the distribution characteristic of stable carbon isotope and the relationship between the change of soil carbon and the distance to oasis of soil organic carbon (SOC) and soil inorganic carbon (SIC), three belt transects were set according to the distance between the desert and the oasis in edge, middle and hinterland of the desert respectively, and collected the soil profile samples with depth of 2 m. The results indicated that the SOC content reduced with the soil depth, and the variation with the distance to oasis was the edge> the middle> the hinterland.