Publications by authors named "Chanyi Jiang"
A developing use of nanotechnology in medicine involves using nanoparticles to administer drugs, genes, biologicals, or other materials to targeted cell types, such as cancer cells. In healthcare, nanotechnology has brought about revolutionary changes in the treatment of various medical and surgical conditions, including in orthopedic. Its clinical applications in surgery range from developing surgical instruments and suture materials to enhancing imaging techniques, targeted drug delivery, visualization methods, and wound healing procedures.
View Article and Find Full Text PDFGlobally, an annual count of more than two million bone transplants is conducted, with conventional treatments, including metallic implants and bone grafts, exhibiting certain limitations. In recent years, there have been significant advancements in the field of bone regeneration. Oxygen tension regulates cellular behavior, which in turn affects tissue regeneration through metabolic programming.
View Article and Find Full Text PDFNanotechnology-based bone regeneration in orthopedics: a review of recent trends.
Nanomedicine (Lond)
February 2024
Nanotechnology has revolutionized the field of bone regeneration, offering innovative solutions to address the challenges associated with conventional therapies. This comprehensive review explores the diverse landscape of nanomaterials - including nanoparticles, nanocomposites and nanofibers - tailored for bone tissue engineering. We delve into the intricate design principles, structural mimicry of native bone and the crucial role of biomaterial selection, encompassing bioceramics, polymers, metals and their hybrids.
View Article and Find Full Text PDFThe objective of bioimplant engineering is to develop biologically compatible materials for restoring, preserving, or altering damaged tissues and/or organ functions. The variety of substances used for orthopedic implant applications has been substantially influenced by modern material technology. Therefore, nanomaterials can mimic the surface properties of normal tissues, including surface chemistry, topography, energy, and wettability.
View Article and Find Full Text PDFArticle Synopsis
- - The use of biodegradable polymers in treating bone diseases is gaining traction in biomedicine, aided by advancements in materials technology and the popularity of 3D printing for creating orthopedic implants.
- - 3D printing allows for the production of patient-specific orthopedic and dental implants, with many already receiving FDA approval, displaying benefits like cost-effectiveness and the ability to create complex structures.
- - There's a growing focus on using biodegradable metals like magnesium and iron in implants, addressing current limitations with traditional metals, while also exploring future challenges and possibilities in 3D printing applications in orthopedics.
Recent developments in nanomaterials for upgrading treatment of orthopedics diseases.
Front Bioeng Biotechnol
August 2023
Article Synopsis
- * Recent advancements in nanomedicine have led to innovative approaches for disease detection and treatment, with engineered nanomaterials improving the targeted delivery of drugs and reducing toxicity.
- * Although there are considerable challenges to the commercialization of nanotechnology in orthopedics, its potential to transform cure and diagnosis remains largely untapped and promising.