Publications by authors named "Chanxiu Li"

Article Synopsis
  • The study aimed to evaluate the effectiveness and safety of excimer laser (EL) combination therapies for repigmentation in vitiligo patients.
  • A systematic review of randomized controlled trials found that EL with antioxidants showed the highest repigmentation rates (98.8%), while EL alone had the highest treatment failure rates (77.6%).
  • Mild adverse effects like erythema and burning were common across all treatment groups, indicating that these combination therapies are generally safe.
View Article and Find Full Text PDF

Objectives: To evaluate the efficacy and safety of macrolide antibiotics therapy in patients with chronic rhinosinusitis (CRS) receiving endoscopic sinus surgery.

Data Sources: PubMed, Web of Science, Embase, and Cochrane Library.

Review Methods: The electronic databases were comprehensively searched on June 2, 2022, for randomized controlled trials on macrolide antibiotics in the treatment of patients undergoing CRS endoscopic surgery.

View Article and Find Full Text PDF

Erectile dysfunction (ED) and chronic periodontal disease (CPD) share mutual risk factors, and the incidence of ED is increasing among young adults. The relation of CPD and ED remains obscure due to inconsistent clinical evidence. This study aimed to further assess the relationship between CPD and ED using the Community Periodontal Index of Treatment Need (CPITN) and the International Index of Erectile Function (IIEF).

View Article and Find Full Text PDF

Periodontitis is a chronic infectious disease that causes inflammation and immune response and has an ultimate impact on the health of the whole body. Sirtuin6 (SIRT6) and Krüppel-like factor 5 (KLF5) have been reported to regulate the inflammatory response and play an important role in the development of periodontitis. LPS was adopted to induce periodontal ligament stem cells (PDLSCs) to construct a periodontitis cell model.

View Article and Find Full Text PDF
Article Synopsis
  • Periodontitis (PD) is a chronic gum disease linked to increased prevalence among patients with rheumatoid arthritis (RA), necessitating an examination of their correlation.
  • A study involving 307 RA patients and 324 healthy controls revealed a significantly higher incidence of PD in the RA group (51.5%) compared to controls (31.2%), with increased levels of inflammation markers such as IL-1β and TNF-α in the RA and PD group.
  • Findings suggest that the presence of RA not only elevates the risk of developing PD but is also associated with heightened inflammatory responses in the gingival crevicular fluid.
View Article and Find Full Text PDF

Aim: This study was aimed to investigate the role of TUG1 in LPS-stimulated hPDLCs and to evaluate the potential functions of TUG1 in the pathogenesis of periodontitis.

Methods: LPS-stimulated hPDLCs were established as the cell model. CCK-8 assay was performed to assess cell proliferation ability.

View Article and Find Full Text PDF

Motivation: Neuroimaging genetics identifies the relationships between genetic variants (i.e., the single nucleotide polymorphisms) and brain imaging data to reveal the associations from genotypes to phenotypes.

View Article and Find Full Text PDF

Neuroimaging genetics is an emerging field that aims to identify the associations between genetic variants (e.g., single nucleotide polymorphisms (SNPs)) and quantitative traits (QTs) such as brain imaging phenotypes.

View Article and Find Full Text PDF