[On the use of type I tropocollagen for local injection therapy of spine, upper and lower extremity disorders].

A meeting of Interdisciplinary Expert Panel with leading specialists in the field of orthopedics/traumatology, surgery, rheumatology, and neurology was held in Moscow on February 10, 2023. The purpose of the meeting was to discuss the current status of local injection therapy (LIT) in Russia and the rationale behind the use of collagen-based products for various musculoskeletal disorders. The experts considered the following issues: (1) General contraindications to the use of medical products based on tropocollagen as well as an algorithm for actions in case of adverse events; (2) Guidelines regarding LIT in general and LIT using tropocollagen in particular, including in combination with other LIT products; (3) Particular indications and approaches to the treatment of patients with abnormal changes in appendicular joints and spine with damage to both intra-articular structures and periarticular soft tissue.

[Errors and complications of total endoprosthesis of the knee joint with the prostheses "Waldemar Link"].

The article presents results of an analysis of errors and complications for total endoprosthesing different pathological states of the knee joint with prostheses "Waldemar Link". The causes of early and late complications were found. The authors have developed original means for prevention and treatment of them.

[A differentiated approach to the treatment of stable contractures of the knee joints].

An analysis of results of treatment of 120 patients with contractures of the knee joints of different severity was made. The method of performing less traumatic surgical treatment of such patients is described. The results obtained were positive.

[Changes in the composition and properties of the joint contents in hemophilic arthropathies during local invasive therapy].

An immunological study has been made in 47 hemophiliacs with arthropathies receiving local invasive therapy. Joint contents were examined in 20 patients with acute hemarthrosis, 10 patients with exudative synovitis and 11 ones with proliferative synovitis. Under the protection of cryoprecipitate (5 U/kg) all the patients underwent joint puncture with removal of the contents, lavage of the synovial cavity and intraarticular injection of 50 mg of hydrocortisone.