Publications by authors named "Chantrapa Sriswasdi"

Background: Secondary acute myeloid leukemia (sAML) and AML with myelodysplasia-related changes (AML-MRC) both result in dismal outcomes. This retrospective study aimed to determine whether these features are poor prognostic factors independent of older age and adverse cytogenetics, which are commonly associated with a poor prognosis.

Methods: The characteristics and real-world outcomes of sAML and AML-MRC from the Thai AML registry database were investigated.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted using data from the Thai AML registry to evaluate the effectiveness of different doses of cytarabine in treating patients with acute myeloid leukemia (AML) after achieving complete remission.
  • The median relapse-free survival (RFS) and overall survival (OS) were slightly different among the three doses (IDAC 1.5 g/m, HiDAC 2 g/m, and HiDAC 3 g/m), but no significant differences were found.
  • The study concluded that IDAC is a suitable postremission treatment, while higher doses do not offer additional benefits and may increase the risk of complications such as septic shock, emphasizing that the number of treatment cycles is more crucial than the dosage.
View Article and Find Full Text PDF

Background: Acute myeloid leukemia (AML) is a common, challenging hematologic malignancy worldwide. Thai data on its characteristics and outcomes have never been systematically reported, to our knowledge. The objective of this study was to determine the clinical features and outcomes of Thai patients with AML.

View Article and Find Full Text PDF

Objective: To determine the clinical outcomes of an aggressive combined cooling technique for exertional heatstroke in Thailand.

Methods: We analyzed patients who were diagnosed with exertional heatstroke between 1995 and 2007. Outcomes were assessed both in hospital and at 3 months follow-up.

View Article and Find Full Text PDF

Standard-dose (2 mg/day) oral granisetron seems to have more antiemetic efficacy than that of high-dose (0.5-1 mg/kg/dose) metoclopramide in moderately emetogenic chemotherapy. However, the cost of oral granisetron is much higher than that of metoclopramide so the authors tried to overcome this disadvantage by dose reduction and adding dexamethasone to enhance the antiemetic effect of oral granisetron.

View Article and Find Full Text PDF