Publications by authors named "Chantal K Gutknecht"
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Synopsis of recent research by authors named "Chantal K Gutknecht"
- Chantal K Gutknecht's research primarily focuses on advanced in vitro antibody display technologies, particularly in the context of discovering and engineering clinically viable full-length IgG antibodies.
- Her notable work, titled "Transpo-mAb display," introduces a novel mammalian cell-based platform that utilizes non-viral transposition technology to efficiently generate and screen antibody libraries for high-quality candidates suitable for clinical applications.
- The study emphasizes the advantages of using DNA-transposable vectors with large cargo capacity to enable stable expression of antibody constructs, significantly enhancing the selection process for functional antibodies through natural mechanisms of B cell expression.
