Autologous Fibrin-Base Scaffold for Chondrocytes and Bone Marrow Mesenchymal Stem Cells Implantation: The Development and Comparison to Conventional Fibrin Glue.

Objective: The authors developed the autologous fibrin-base scaffold for chondrocytes and bone marrow mesenchymal stem cells (BM-MSCs) implantation and evaluated cells viability in autologous fibrin-base scaffold comparing to commercial fibrin glue.

Material And Method: The chondrocytes and BM-MSCs were seeded into autologous fibrin-base scaffold and commercial fibrin glue. The cell viability and proliferation were evaluated at 1 and 7 days.

Autologous bone marrow mesenchymal stem cells implantation for cartilage defects: two cases report.

Objective: The authors reported the results of autologous bone marrow mesenchymal stem cells (BM-MSCs) implantation in two patients with large traumatic cartilage defects of the knee.

Material And Method: Two patients with grade 3-4 according to the International Cartilage Repair Society Classification System were performed autologous bone marrow mesenchymal stem cells (BM-MSCs) implantation on December 2007 and January 2008. The bone marrow aspiration was performed in the outpatient visit under local anesthesia and sent to the laboratory for BM-MSCs isolation and expansion.

Autologous chondrocytes implantation with three-dimensional collagen scaffold.

Objective: The authors report a patient with large traumatic knee cartilage defects treated with autologous chondrocytes implantation (ACI) in three-dimensional collagen scaffold.

Material And Method: A patient with grade 3-4 according to ICRS (International Cartilage Repair Society) Classification System was performed ACI with three-dimensional collagen scaffold. The two-stage procedure was performed First, the cartilage was arthroscopic harvested.

Autologous chondrocytes implantation for traumatic cartilage defects of the knee.

Objective: To evaluate the results of autologous chondrocytes implantation in the patients with large traumatic cartilage defects of the knee.

Material And Method: Five patients (six knees) with grade 3-4 according to International Cartilage Repair Society Classification System were performed ACI between May 2006 and April 2007. The two-stage procedure was performed.

Arthroscopic outside-in meniscal repair through a needle hole.

This article describes an alternative method for outside-in repair of a longitudinal meniscal tear through a needle hole, which will produce an almost negligible cutaneous scar. The procedure is performed under arthroscopic set-up using an 18-gauge needle preloaded with appropriate suture material. Insert the needle twice through the same cutaneous entry hole to form a mattress loop across the torn meniscal segments.