Publications by authors named "Chanmei Shi"
Background: Sarcopenia is an age-related syndrome that can impact the physical and mental health of older adults. However, it is often overlooked in clinical practice. Therefore, we aim to construct a nomogram based on simplified discriminant parameters for screening older adult patients for sarcopenia risk.
View Article and Find Full Text PDFBackground: We compared the cryptococcal antigen detection and imaging findings between immunocompetent and immunocompromised patients in whom pulmonary cryptococcosis had been diagnosed. The aim of our study was to determine whether the patient's immune status and radiography affect the detection of cryptococcal antigen.
Methods: According to whether they took immunosuppressive drugs or not, seventy and eight adult patients with pulmonary cryptococcosis were divided into two groups: the immunocompetent group and the immunocompromised group.
Article Synopsis
- Epidemiological studies have linked exposure to particulate matter (PM2.5) with oxidative stress and various health issues, particularly lung injuries, highlighting the need for preventive measures against these hazards.
- * The research aims to explore whether curcumin can protect against oxidative stress and inflammation from PM2.5 by activating the HO-1/CO/P38 MAPK signaling pathway.
- * In the experiment, mice were exposed to PM2.5 to evaluate lung damage and assess the protective effects of curcumin through various biological measurements, revealing significant enhancement of the HO-1/CO/P38 MAPK pathway in treated groups.
[Curcumin suppresses cigarette smoke extract-induced oxidative stress through PPARγ/ NF-κB pathway in human bronchial epithelial cells ].
Nan Fang Yi Ke Da Xue Xue Bao
September 2018
Objective: To investigate the effect of curcumin against cigarette smoke extract (CSE)- induced oxidative stress in human bronchial epithelial cells and explore the underlying mechanism.
Methods: Human bronchial epithelial cell line 16HBE was treated for 24 h with curcumin, CSE, CSE + curcumin, and CSE + curcumin with transfection by a short hairpin RNA targeting PPARγ (shPPARγ). MTT assay was used to observe the changes in the cell viability after the treatments.