Methylene Blue-Mediated Antimicrobial ​Photodynamic Therapy Against Clinical Isolates of Extensively Drug Resistant ​Gram-Negative Bacteria Causing Nosocomial Infections in Thailand, An Study.

Background/purpose: Some multidrug-resistant gram-negative bacteria as a global threat have been recently prioritized for research and development of new treatments. We studied the efficacy of methylene blue-mediated antimicrobial photodynamic therapy (MB-aPDT) for the reduction of extensively drug-resistant (XDR-AB) and (XDR-PS) and multidrug-resistant (MDR-KP) isolated in a university hospital setting in Thailand.

Method: Two isolates of each selected bacterium were collected, XDR-AB1 and AB2, XDR- PS1 and PS2, and MDR-KP1 and KP2.

Nagashima-Type Palmoplantar Keratosis with Compound Heterozygous Mutations in SERPINB7.

Nagashima-type palmoplantar keratosis (NPPK) is a diffuse, non-syndromic (isolated), autosomal recessive palmoplantar keratoderma (PPK) with transgredients. It is characterized by non-progressive mild to moderate transgredient PPK. The mutation in is reported to underlie the condition.

Topical 15% Zinc Oxide Ointment Significantly Reduces the Size of Common Warts After Four Weeks: A Randomized, Triple-blinded, Placebo-controlled Trial.

There are limited number of topical agents for the treatment of common warts. Few reports show efficacy of zinc oxide for such indication. We sought to evaluate the efficacy of topical 15% zinc oxide ointment for the reduction in size of common warts.

The Correlations between Follicular Fluorescence and Casual Sebum Levels in Subjects with Normal Skin.

Performing objective measurements of skin oiliness requires a device that can directly measure the sebum level on the skin surface, while ultraviolet-induced red fluorescence (UVRF) can be used to indirectly assess the oiliness on the skin. There have been reports showing the association between these two methods in subjects with oily skin, acne-prone skin, but not in subjects with normal skin. We sought to study the association between UVRF and casual sebum level in terms of assessing the facial oiliness in individuals with normal skin.

A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects.

Background: Acne is one of the most common skin problems among human populations. A facial cleanser formulated with alkyl ether carboxylate (AEC) and alkyl carboxylate (AC) can improve acne by cleansing sebum on facial skin but cannot effectively remove keratotic plugs in the skin pores. Recently, we confirmed that Tris (hydroxymethyl) aminomethane and L-arginine (Tris/Arg) is able to reduce sebum levels, disrupt keratotic plugs in vitro and decrease pore size on facial skin.