Publications by authors named "Chanjun Zhen"

Purpose: To explore the recurrence pattern and risk factors associated with the relapse of thoracic esophageal squamous cell carcinoma (TESCC) among patients who received esophagectomy following neoadjuvant immunochemotherapy (NICT).

Methods: A total of 191 TESCC patients who received esophagectomy following NICT were retrospectively reviewed from 2019 to 2022. The first recurrence patterns were assessed.

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Article Synopsis
  • The study aimed to assess the effectiveness of adjuvant radiotherapy in esophageal cancer patients who had undergone surgery after receiving neoadjuvant chemoradiotherapy between 2004 and 2019.
  • Analysis used data from the SEER database, categorizing patients into those receiving adjuvant radiotherapy (with or without chemotherapy) and those receiving only chemotherapy, using propensity score matching for accuracy.
  • Results showed no significant differences in overall survival or cancer-specific survival between the treatment groups, although certain patients with more advanced tumors did benefit from radiotherapy.*
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An esophageal fistula can be caused by an esophageal tumor as well as the surgery, radiotherapy (RT), or chemoradiotherapy used to treat the tumor. The most dangerous complications are massive hemoptysis and asphyxia. This report describes a 58-year-old man with a >1-month history of dysphagia and hemoptysis.

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Article Synopsis
  • * A 55-year-old man with coughing and shortness of breath was diagnosed with BALT lymphoma via bronchoscopy and biopsy, leading to a recommendation for radiotherapy.
  • * Following treatment, the patient exhibited no significant side effects, and subsequent scans indicated no recurrence, highlighting the disease's good prognosis and the effectiveness of non-invasive diagnostic methods like computed tomography virtual bronchoscopy (CTVB).
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Purpose: To evaluate the clinical outcomes of salvage radiotherapy in patients with supraclavicular lymph node (SCLN) metastases after esophagectomy.

Methods: After initial esophagectomy (R0 resection), clinical outcomes in patients with esophageal squamous cell carcinoma with SCLN metastases during follow-up were retrospectively analyzed.

Results: A total of 114 patients were split into two groups: the salvage radiotherapy (SR) (n=89) and the control (NSR) (without salvage radiotherapy, n=25).

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Objective: Retrospectively analyzed the esophageal carcinoma (EC) patients with esophageal perforation (EP) after radiotherapy to discuss the treatment and prognosis.

Methods: Data of patients with EC who had EP after radiotherapy in Hebei Cancer Hospital were collected from 2001 to 2020 and retrospectively analyzed. All analyses were performed using SPSS Statistics for Windows, version 18.

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Background: Recently, an increasing number of cases with transformation from lung adenocarcinoma to small cell lung cancer (SCLC) have been identified, but few studies have investigated the clinical, pathological as well as molecular characteristics of these cases. This study aimed to summarize and analyze these features.

Methods: We retrospectively collected data including clinical information, laboratory examination results, radiological and pathological findings of ten patients, who were confirmed to undergo SCLC transformation following treatment from January 2014 to January 2020.

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Purpose: The aim of this study was to evaluate the salvage radiotherapy outcome in patients with local recurrent esophageal cancer after radical radiochemotherapy (RCT).

Methods: A total of 114 patients with local recurrent esophageal squamous cell carcinoma after initial radical RCT were retrospectively analyzed. Fifty-five (55) patients belonged to the salvage radiotherapy group (SR group) and 59 patients to the non-salvage radiotherapy group (NSR group).

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