Home infusion therapy is safe and enhances compliance in patients with mucopolysaccharidoses.

The transition to home infusion therapy is described in 11 patients with mucopolysaccharide (MPS) disorders initially treated with enzyme replacement therapy (ERT) in an out-patient infusion center. Home therapy was well tolerated with no infusion-related reactions (IRR) occurring in 671 patient-weeks of treatment. In addition, compliance with the weekly treatment regimen was improved in patients on home therapy.