-Feruloyl Serotonin Attenuates Neuronal Oxidative Stress and Apoptosis in Aβ-Treated Human Neuroblastoma SH-SY5Y Cells.

Amyloid-beta (Aβ) aggregation and deposition have been identified as a critical feature in the pathology of Alzheimer's disease (AD), with a series of functional alterations including neuronal oxidative stress and apoptosis. -feruloyl serotonin (FS) is a plant-derived component that exerts antioxidant activity. This study investigated the protective effects of FS on Aβ-treated neuronal damage by regulation of oxidative stress and apoptosis in human neuroblastoma SH-SY5Y cells.

Herbal Mixture of L. Seed and Attenuates Amyloid Beta-Induced Cognitive Dysfunction In Vivo.

Deposition of amyloid-beta (Aβ) in the aging brain has been often observed and is thought to be a pathological feature of Alzheimer's disease. The use of natural products for disease prevention and treatment is gaining attention worldwide. L.

Artificial Intelligence-Based Recognition of Different Types of Shoulder Implants in X-ray Scans Based on Dense Residual Ensemble-Network for Personalized Medicine.

Re-operations and revisions are often performed in patients who have undergone total shoulder arthroplasty (TSA) and reverse total shoulder arthroplasty (RTSA). This necessitates an accurate recognition of the implant model and manufacturer to set the correct apparatus and procedure according to the patient's anatomy as personalized medicine. Owing to unavailability and ambiguity in the medical data of a patient, expert surgeons identify the implants through a visual comparison of X-ray images.

Deep Learning-Based Multinational Banknote Type and Fitness Classification with the Combined Images by Visible-Light Reflection and Infrared-Light Transmission Image Sensors.

Automatic sorting of banknotes in payment facilities, such as automated payment machines or vending machines, consists of many tasks such as recognition of banknote type, classification of fitness for recirculation, and counterfeit detection. Previous studies addressing these problems have mostly reported separately on each of these classification tasks and for a specific type of currency only. In other words, there has been little research conducted considering a combination of these multiple tasks, such as classification of banknote denomination and fitness of banknotes, as well as considering a multinational currency condition of the method.

Repair of rabbit radial bone defects using bone morphogenetic protein-2 combined with 3D porous silk fibroin/β-tricalcium phosphate hybrid scaffolds.

Our study aimed to investigate the effect of bone morphogenetic protein-2 (BMP-2) bound to silk fibroin and β-tricalcium phosphate (SF/β-TCP) hybrid on the healing of critical-size radial defects in rabbits. A 15-mm critical-size defect was induced at mid-diaphysis in the left radius of 20 New Zealand white rabbits (average age, 3.5 months; weight, 2.

Beraprost enhances the APC function of B cells by upregulating CD86 expression levels.

Lipid mediators are emerging as important regulators of the immune system. Based on our previous result that shows strong expression of prostacyclin synthase in the germinal center, we investigated whether prostacyclin would regulate the APC function of B cells. Owing to the very short half-life of prostacyclin in experimental conditions, we used a more stable analog, beraprost.

Usefulness of ultrasonography in the treatment of nasal bone fractures.

Background: Ultrasonography has recently been used in assessment and diagnosis of maxillofacial trauma because it is easy and quick to perform, inexpensive, portable, and noninvasive. The aim of this study was to estimate ultrasonography as an intraoperative repositioning control of nasal bone fractures.

Methods: We studied 32 patients with suspected nasal bone fracture.

Expression of CD320 in human B cells in addition to follicular dendritic cells.

CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. Although CD320 is known to enhance proliferation of germinal center (GC) B cells, little other information is available. In this study, we investigated its cellular distribution in the GC.

Prostacyclin production is not controlled by prostacyclin synthase but by cyclooxygenase-2 in a human follicular dendritic cell line, HK.

We have recently demonstrated that human follicular dendritic cells (FDCs) strongly express prostacyclin synthase. The purpose of this study is to investigate the production mechanism of prostacyclin using the established human FDC line, HK. The levels of PGIS protein expression did not vary during the different stages of the cell cycle.