Preparation and characterization of multilayered microcapsules of Lactobacillus rhamnosus encapsulated with sodium alginate, hyaluronic acid and carrageenan and their protective effects on the retina.

To improve the activity of probiotics during oral delivery and to investigate the protective effects on the retina. In this study, multilayer microcapsules encapsulating Lactobacillus rhamnosus YBT20 (YBT20) were prepared using sodium alginate, carrageenan and hyaluronic acid. Then it was characterized by determining the encapsulation rate, particle size distribution and zeta potential, and the results showed that the encapsulation rate of YBT20 by microcapsules was 68.