Preparation and Performance of H-PDMS/PMHS/OTS Hybrid Nanosilica Hydrophobic and Self-Cleaning Coatings on Phosphogypsum Surface.

Hemihydrate phosphogypsum, an industrial solid waste product of phosphoric acid production, is abundant and inexpensive. If the problem of poor water resistance is solved, this material could be substituted for cement and other traditional energy-consuming cementitious materials in the construction industry. This approach would confer important economic and environmental benefits while promoting the resource utilization of phosphogypsum (PG).

Lanthanides-Substituted Hydroxyapatite/ Composite Coated Titanium Plate for Bone Tissue Regeneration.

Purpose: To develop the surface-treated metal implant with highly encouraged positive properties, including high anti-corrosiveness, bio-activeness and bio-compatibleness for orthopedic applications.

Methods: In this work, the surface of commercially pure titanium (Ti) metal was treated with bio-compatible polydopamine (PD) by merely immersing the Ti plate in PD solution. The composite of trivalent lanthanide minerals (La, Ce and Gd)-substituted hydroxyapatite (MHAP) with (AV) gel was prepared and coated on the PD-Ti plate by electrophoretic deposition (EPD) method.

Synthesis of Biscoumarin and Dihydropyran Derivatives and Evaluation of Their Antibacterial Activity.

In an attempt to find a new class antibacterial agents, a series of biscoumarins (1-4) and dihydropyrans (5-13) were successfully prepared. The molecular structures of four representative compounds, that is, 4, 5, 8 and 12 were confirmed by single crystal X-ray diffraction study. These synthesized compounds were screened for their antibacterial activity in vitro against Staphylococcus aureus (S.

A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts.

Dysregulated microRNAs in osteoclasts could cause many skeletal diseases. The therapeutic manipulation of these pathogenic microRNAs necessitates novel, efficient delivery systems to facilitate microRNAs modulators targeting osteoclasts with minimal off-target effects. Bone resorption surfaces characterized by highly crystallized hydroxyapatite are dominantly occupied by osteoclasts.

Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway.

Osteosarcoma is a high-grade malignant bone tumor. Pterostilbene (PTE) is a natural, dimethylated analog of resveratrol with higher bioavailability. While PTE has been shown to have potent antitumor activity against various types of cancer, the molecular mechanisms underlying the effects of PTE remain largely unknown.

Posterior rotating rod reduction strategy for irreducible atlantoaxial subluxations with congenital odontoid aplasia.

Study Design: Applying rotating rod techniques to reduce irreducible atlantoaxial dislocation.

Objective: To spare the occipital-C1 motion by the strategy in reduction of before surgery irreducible atlantoaxial dislocation with obvious neurologic symptoms and congenital odontoid aplasia.

Summary Of Background Data: The treatment of atlantoaxial dislocation (AAD) is a challenging problem for most surgeons.

Tanshinone IIA improves impaired nerve functions in experimental diabetic rats.

Diabetic neuropathy is one of the most common complications in diabetes mellitus. Thus far, effective therapeutic agents for restoring the impaired motor and sensory nerve functions in diabetic neuropathy are still lacking. The antioxidant and neuroprotective properties of tanshinone IIA make it a promising candidate for the treatment of diabetic neuropathy.