Publications by authors named "Changtian Li"

Sarcomyxa edulis, a notable edible and medicinal mushroom indigenous to northeast China, is celebrated for its high nutritional value and delightful taste. In this study, white light as a control and examined the effects of red, green, and blue light on the agronomic traits, antioxidant capabilities, and nutritional composition of S. edulis.

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Background: Cobweb disease is a fungal disease that commonly affects the cultivation and production of edible mushrooms, leading to serious yield and economic losses. It is considered a major fungal disease in the realm of edible mushrooms. The symptoms of cobweb disease were found during the cultivation of Lyophyllum decastes.

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Background: Malignant liver tumors seriously endanger human health. Among different therapeutic approaches, high-frequency irreversible electroporation (H-FIRE) is a recently emerging tumor ablation technique. The objective of this study was to evaluate the feasibility and safety of ultrasound-guided percutaneous H-FIRE using four electrode needles in porcine livers.

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Three new griseofulvin derivatives, griseofulvinoside A-C (-), were isolated from the ethyl acetate extract of the solid fermentation product of . Their structures were elucidated based on extensive spectroscopic data analysis of MS, 1D and 2D NMR. The antifungal activities of new compounds were evaluated against four phytopathogenic fungi , and all test compounds demonstrated inhibitory effects.

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In this study, a polysaccharide known as PAPS2 was eluted from fruiting bodies using 0.1 M NaCl solutions. PAPS2 has a of 19.

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Green mold disease, caused by spp., is one of the most devastating diseases of mushrooms in China. The application of fungicides remains one of the important control methods among the integrated pest management tools for disease management in mushroom farms.

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In recent years, the optimization of straw-rotting formulations for cultivating edible mushrooms and the management of the resulting spent mushroom substrate have emerged as new challenges. This study aimed to investigate the composting of spent mushroom substrate produced from mushroom cultivation with various straw additions, under conditions where chicken manure was also used. Parameters measured during the composting process included temperature, pH, electrical conductivity (EC), germination index (GI), moisture, and total nitrogen content.

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This study investigated the effects of different concentrations of biological maturity agents on the composting process of Auricularia heimuer residue by adding them to the composting process. By measuring the changes in physical and chemical indicators and microbial diversity during composting, the results showed that the addition of biological maturity agents had a certain promoting effect on compost temperature, humidity, pH, seed germination index, and vitality index. Appropriate composting days can promote the accumulation of ammonium nitrogen.

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Inadequate angiogenesis and inflammation at the wound site have always been a major threat to skin wounds, especially for diabetic wounds that are difficult to heal. Therefore, hydrogel dressings with angiogenesis and antibacterial properties are very necessary in practical applications. This study reported a hydrogel (PCA) based on L-arginine conjugated chitosan (CA) and aldehyde functionalized polysaccharides of Phellinus igniarius (OPPI) as an antibacterial and pro-angiogenesis dressing for wound repair in diabetes for the first time.

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, the generic type of belonging to , is a precious medicinal wood-inhabiting macrofungus with high commercial potential. To facilitate the medicinal utilization of this fungal resource, transcriptome sequences are newly generated from . strain MS2.

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BACKGROUND Intrapancreatic accessory spleen, or splenunculus, is a congenital condition that occurs in up to 2% of the population, with the tail of the pancreas being the second most common site. Imaging alone may not confirm the diagnosis as this can mimic a hypervascular tumor on contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI). This report presents a challenging case of intrapancreatic accessory spleen in the tail of the pancreas in a 64-year-old man.

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, a type of ectomycorrhizal fungi distributed widely in the world, is also an essential category for researching bioactive substances and pharmacological functions. We discovered fruitbodies of covered in a layer of white mycelium in 2020. , a pathogenic fungus related to cobweb disease, was isolated and identified based on morphological and phylogenetic features.

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The optimal ventilatory strategy for the face mask ventilation during anesthesia induction is still unknow. We evaluated the effect of two positive end-expiratory pressure (PEEP) levels (0 cmHO and 6 cmHO) and two oxygen concentration levels (1.0 and .

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Wild edible mushrooms are a huge source to discover bioactive natural products. In this work, one new polyprenylphenol derivative, termed 2-geranylgeranyl-1,4-benzenediol 1-O-acetate (1), together with eight known compounds (2-9) were isolated from wild edible mushroom Suillus luteus. The structure of new compound was elucidated by high-resolution electrospray ionization mass spectroscopy and nuclear magnetic resonance data.

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Background: Gastric cancer has a high incidence and mortality rate. Angiogenesis is necessary for tumor infiltration and metastasis and affects patient prognosis. YKL-39 has monocyte chemotactic activity and pro-angiogenic activity in some tumors.

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The developmental transcriptomes of Sarcomyxa edulis were assessed to explore the molecular mechanisms underlying lignocellulose degradation. Six stages were analyzed, spanning the entire developmental process: growth of mycelium until occupying half the bag (B1), mycelium under low-temperature stimulation after occupying the entire bag (B2), appearance of mycelium in primordia (B3), primordia (B4), mycelium at the harvest stage (B5), and mature fruiting body (B6). Samples from all six developmental stages were used for transcriptome sequencing, with three biological replicates for all experiments.

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Article Synopsis
  • Researchers purified a water-soluble polysaccharide called PAPS1 from mushroom fruiting bodies and studied its effects on immunosuppressed mice caused by cyclophosphamide (CTX).
  • After 28 days of treatment, PAPS1 improved immune markers, reduced oxidative stress, and enhanced beneficial gut bacteria linked to immunity, all while increasing levels of key immune cytokines in the mice.
  • The study suggests that PAPS1 may boost immunity by enhancing the Nrf2 signaling pathway, indicating its potential as an immunomodulatory therapy.
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Dictyostelid cellular slime molds (dictyostelids) are protists that are common inhabitants of most soils, where they feed upon bacteria. Changbai Mountain is the highest mountain in northeast China. Soil samples collected on Changbai Mountain yielded 11 isolates representing six species of dictyostelid samples.

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Here, we report the characterization of a novel (-)ssRNA mycovirus isolated from Auricularia heimuer CCMJ1222, using a combination of RNA-seq, reverse transcription polymerase chain reaction, 5' and 3' rapid amplification of cDNA ends, and Sanger sequencing. Based on database searches, sequence alignment, and phylogenetic analysis, we designated the virus as "Auricularia heimuer negative-stranded RNA virus 1" (AhNsRV1). This virus has a monopartite RNA genome related to mymonaviruses (order Mononegavirales).

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The cultivation of was studied by different methods, such as puncturing and fixed-point mushroom production, shading treatment at the top of the bag, and pulling the top of the bag. The agronomic characters, yield, nutritional components, and antioxidant activities of fruiting bodies of were determined. The results showed that the number of buds in the perforated treatment was less than that in the production method of traditional fruiting bodies to a certain extent.

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Background: Gastric cancer (GC) is the fifth most common malignant tumor and the third leading cause of cancer-related deaths. Because GC has the characteristics of high heterogeneity, unclear mechanism, limited treatment methods, and low five-year survival rate, it is necessary to find the prognostic biomarkers of GC and explore the mechanism of GC.

Methods: We first identified differentially expressed genes (DEGs) between gastric cancer and normal gastric cells through expression analysis.

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China is one of the largest producers and exporters of wild edible fungi in the world. Cultivation mushroom production value ranks within the top five after grain, vegetable, fruit, and edible oil plantation, greater than sugar, cotton, and tobacco business. More than 40 new varieties of high market value mushrooms from our group were highlighted in this article.

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Background: Gastric adenocarcinoma (GAD) is one of the most common tumors in the world and the prognosis is still very poor.

Objective: We sought to identify reliable prognostic biomarkers for the progression of GAD and the sensitivity to drug therapy.

Method: The RNA sequencing data of GAD was downloaded from the Cancer Genome Atlas (TCGA) database and used for analysis.

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Nine collections of gymnopoid fungi were studied based on morpho-molecular characteristics. The macromorphology was made according to the photograph of fresh basidiomata and field notes, while the micromorphology was examined via an optical microscope. Simultaneously, the phylogenetic analyses were performed by maximum likelihood and Bayesian inference methods based on a combined dataset of nrITS1-nr5.

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