Publications by authors named "Changshuo Wang"

The present research uncovers the shared genetic underpinnings of fairness norm adaptation capability, its neural correlates, and long-term mental health outcomes. One hundred and eighty-six twins are recruited and played as responders in the Ultimatum Game (UG) while undergoing fMRI scanning in their early adulthood (Study-1) and are measured on depressive symptoms eight years later (Study-2). With computational modeling, the process of norm adaptation is differentiated from that of fairness valuation in UG.

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Article Synopsis
  • This study examined how the functional connectivity of the subgenual anterior cingulate cortex (sgACC) can predict the effectiveness of antidepressant treatment in patients with major depressive disorder (MDD).
  • Eighty-seven patients who hadn't taken medication were scanned using MRI, and after 12 weeks of escitalopram treatment, they were classified into remission and non-remission groups.
  • Results showed that higher connectivity between the sgACC and areas in the fronto-parietal network was linked to better treatment outcomes, indicating that analyzing sgACC connectivity could aid in developing personalized treatment plans.
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Recently, point cloud domain adaptation (DA) practices have been implemented to improve the generalization ability of deep learning models on point cloud data. However, variations across domains often result in decreased performance of models trained on different distributed data sources. Previous studies have focused on output-level domain alignment to address this challenge.

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Background: The different symptoms of major depressive disorder (MDD) in adolescents compared to adults suggested there may be differences in the pathophysiology between adolescents and adults with MDD. However, despite the amygdala being considered critical in the pathophysiology, there was limited knowledge about the commonalities and differences in the resting-state functional connectivity (rsFC) of amygdala subregions in MDD patients of different age groups.

Methods: In the current study, 65 adolescents (46 with MDD and 19 controls) and 91 adults (35 with MDD and 56 controls) were included.

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  • There is currently a lack of cross-species brain atlases, making it difficult to compare brain connectivity patterns directly between humans and chimpanzees.
  • The newly developed Chimpanzee Brainnetome Atlas (ChimpBNA) revealed significant connectivity divergences in areas like the lateral temporal and dorsolateral prefrontal cortex, with genetic factors that could explain these differences in brain connectivity patterns. *
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The rhesus macaque (Macaca mulatta) is a crucial experimental animal that shares many genetic, brain organizational, and behavioral characteristics with humans. A macaque brain atlas is fundamental to biomedical and evolutionary research. However, even though connectivity is vital for understanding brain functions, a connectivity-based whole-brain atlas of the macaque has not previously been made.

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Comprising numerous subnuclei, the thalamus intricately interconnects the cortex and subcortex, orchestrating various facets of brain functions. Extracting personalized parcellation patterns for these subnuclei is crucial, as different thalamic nuclei play varying roles in cognition and serve as therapeutic targets for neuromodulation. However, accurately delineating the thalamic nuclei boundary at the individual level is challenging due to intersubject variability.

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A proposed method, Enhancement, integration, and Expansion, aims to activate the representation of detailed features for occluded person re-identification. Region and context are two important and complementary features, and integrating them in an occluded environment can effectively improve the robustness of the model. Firstly, a self-enhancement module is designed.

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