Incidence and risk factor analysis for sarcopenia in patients with cancer.

The objective of the present study was to investigate the incidence of and possible risk factors associated with sarcopenia among cancer patients. Patients with cancer were examined through the use of lumbar magnetic resonance imaging, and clinical data was collected between September and December, 2012, at Jilin Province Tumor Hospital (Changchun, China). The data was subsequently compared between patients with and without sarcopenia.

Silica-encapsulated Gd3+-aggregated gold nanoclusters for in vitro and in vivo multimodal cancer imaging.

Gd(3+)-aggregated gold nanoclusters (AuNCs) encapsulated by silica shell (Gd(3+)-A-AuNCs@SiO2NPs) were strategically designed and prepared. The as-prepared nanoparticles exhibit aggregation-enhanced fluorescence (AEF), with an intensity that is up to 3.8 times that of discrete AuNCs.

Multifunctional upconversion mesoporous silica nanostructures for dual modal imaging and in vivo drug delivery.

Incorporating the agents for magnetic resonance imaging (MRI), optical imaging, and therapy in one nanostructured matrix to construct multifunctional nanomedical platform has attracted great attention for simultaneous diagnostic and therapeutic applications. In this work, a facile methodology is developed to construct a multifunctional anticancer drug nanocarrier by combining the special advantages of upconversion nanoparticles and mesoporous silica. β-NaYF4 :Yb(3+) , Er(3+) @β-NaGdF4 :Yb(3+) is chosen as it can provide the dual modality of upconversion luminescence and MRI.