Suppressed the Progression of the Clear Cell Renal Cell Carcinoma by Targeting Gene Expression.

Clear cell renal cell carcinoma (ccRCC) is a malignant tumor of kidney epithelial cells, one of the most common tumors in the world. Transforming growth factor beta (TGFβ)1 is a crucial factor that induces epithelial-mesenchymal transition (EMT) in cancer cells. is a microRNA that is considered a tumor suppressor.

Decision Tree-Based Foot Orthosis Prescription for Patients with Pes Planus.

Pes planus, one of the most common foot deformities, includes the loss of the medial arch, misalignment of the rearfoot, and abduction of the forefoot, which negatively affects posture and gait. Foot orthosis, which is effective in normalizing the arch and providing stability during walking, is prescribed for the purpose of treatment and correction. Currently, machine learning technology for classifying and diagnosing foot types is being developed, but it has not yet been applied to the prescription of foot orthosis for the treatment and management of pes planus.

Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.

Background/aims: Hearts from diabetic subjects are susceptible to myocardial ischemia reperfusion (I/R) injury. Propofol has been shown to protect against myocardial I/R injury due to its antioxidant properties while the underlying mechanism remained incompletely understood. Thus, this study aimed to determine whether or not propofol could attenuate myocardial I/R injury by attenuating mitochondrial dysfunction/damage through upregulating Caveolin (Cav)-3 under hyperglycemia.

[Situation and correlated behavior of HIV infection among currently married MSM in Gansu province].

Objective: To explore the situation of HIV infection among currently married MSM and the features of related sexual behavior on both males and females in Gansu province.

Methods: By "Place the recruitment" methodology, 297 currently married MSM were recruited in Lanzhou and Tianshui cities of Gansu province. Participants filled in a questionnaire and underwent HIV antibody testing.