Dual-System Collaborative Model of Prosocial Risky Behavior and Cognitive Computation: A Review.

Prosocial risky behavior (PRB) refers to actions taken at personal risk for the benefit of others or societal welfare, combining risk-taking with prosocial intent, and involving the integrated processing of individual risk and social preferences. Building upon the review and evaluation of the definitions of PRB, existing research tools, theoretical models, and neural mechanisms, this paper elucidates the synergistic interaction and mechanisms of the emotional drive and cognitive reasoning systems in PRB. It constructs a dual-system collaborative model for PRB.

Lactate-related gene signatures as prognostic predictors and comprehensive analysis of immune profiles in nasopharyngeal carcinoma.

Objectives: Nasopharyngeal carcinoma (NPC) is an aggressive malignancy with high rates of morbidity and mortality, largely because of its late diagnosis and metastatic potential. Lactate metabolism and protein lactylation are thought to play roles in NPC pathogenesis by modulating the tumor microenvironment and immune evasion. However, research specifically linking lactate-related mechanisms to NPC remains limited.

Transcriptomic Analysis of Larvae Under High Temperature Stress.

Objectives: Acute temperature stress was explored in through a comprehensive RNA-seq analysis.

Methods: RNA-seq was conducted on 20-day-old after 24 h of temperature stress. Four experimental conditions were established: a control group (18 °C) and three temperature treatment groups (21, 24, and 27 °C).

Effect of Grain Size on Nanometric Cutting of Polycrystalline Silicon via Molecular Dynamics Simulation.

The grain size effect is an important factor in determining the material removal behavior of polycrystalline silicon (p-Si). In the present study, to improve the understanding of nanoscale machining of p-Si, we performed molecular dynamics simulation of nanometric cutting on a p-Si workpiece and discussed the grain size effect on material removal behavior and subsurface damage formation. The simulation results indicate that when cutting on the polycrystal workpiece, the material removal process becomes unstable compared with single crystals.

Gonadal Transcriptome Sequencing Analysis Reveals the Candidate Sex-Related Genes and Signaling Pathways in the East Asian Common Octopus, .

The East Asian common octopus () is an economically important species among cephalopods. This species exhibits a strict dioecious and allogamous reproductive strategy, along with a phenotypic sexual dimorphism, where the third right arm differentiates into hectocotylus in males. However, our understanding of the molecular mechanisms that underlie sex determination and differentiation in this species remains limited.

Small extracellular vesicle CA1 as a promising diagnostic biomarker for nasopharyngeal carcinoma.

Nasopharyngeal carcinoma (NPC), a malignant cancer originating from the epithelial cells of the nasopharynx, presents diagnostic challenges with current methods such as plasma Epstein-Barr virus (EBV) DNA testing showing limited efficacy. This study focused on identifying small extracellular vesicle (sEV) proteins as potential noninvasive biomarkers to enhance NPC diagnostic accuracy. We isolated sEVs from plasma and utilized 4D label-free proteomics to identify differentially expressed proteins (DEPs) among healthy controls (NC = 10), early-stage NPC (E-NPC = 10), and late-stage NPC (L-NPC = 10).

Expediting Next-Generation Hybrid Technology in Recalcitrant Maize Inbreds through In Vivo Targeted Activity of CRISPR/Cas9.

The Manipulated Genic Male Sterile Maintainer (MGM) system, a next-generation hybrid seed technology, enables efficient production of sortable seeds from genic male sterile (GMS) lines. However, implementing robust MGM systems in commercial maize inbred lines requires stable transformation, a genotype-specific and laborious process. This study aimed to integrate MGM technology into the commercial maize inbred line Z372, developing both GMS and MGM lines.

Adaptively identify and refine ill-posed regions for accurate stereo matching.

Stereo matching cost constrains the consistency between pixel pairs. However, the consistency constraint becomes unreliable in ill-posed regions such as occluded or ambiguous regions of the images, making it difficult to explore hidden correspondences. To address this challenge, we introduce an Error-area Feature Refinement Mechanism (EFR) that supplies context features for ill-posed regions.

Interferon-induced transmembrane protein-1 competitively blocks Ephrin receptor A2-mediated Epstein-Barr virus entry into epithelial cells.

Epstein-Barr virus (EBV) can infect both B cells and epithelial cells (ECs), causing diseases such as mononucleosis and cancer. It enters ECs via Ephrin receptor A2 (EphA2). The function of interferon-induced transmembrane protein-1 (IFITM1) in EBV infection of ECs remains elusive.

Safety and efficacy of a low-dose combination of midazolam, alfentanil, and propofol for deep sedation of elderly patients undergoing ERCP.

Background: Proper sedation of patients, particularly elderly individuals, who are more susceptible to sedation-related complications, is of significant importance in endoscopic retrograde cholangiopancreatography (ERCP). This study aims to assess the safety and efficacy of a low-dose combination of midazolam, alfentanil, and propofol for deep sedation in elderly patients undergoing ERCP, compared to a group of middle-aged patients.

Methods: The medical records of 610 patients with common bile duct stones who underwent elective ERCP under deep sedation with a three-drug regimen, including midazolam, alfentanil, and propofol at Shandong Provincial Third Hospital from January 2023 to September 2023 were retrospectively reviewed in this study.

The maize PLASTID TERMINAL OXIDASE (PTOX) locus controls the carotenoid content of kernels.

Carotenoids perform a broad range of important functions in humans; therefore, carotenoid biofortification of maize (Zea mays L.), one of the most highly produced cereal crops worldwide, would have a global impact on human health. PLASTID TERMINAL OXIDASE (PTOX) genes play an important role in carotenoid metabolism; however, the possible function of PTOX in carotenoid biosynthesis in maize has not yet been explored.

Photochemically Controlled Release of the Glucose Transporter 1 Inhibitor for Glucose Deprivation Responses and Cancer Suppression Research.

Cancer cells need a greater supply of glucose mainly due to their aerobic glycolysis, known as the Warburg effect. Glucose transport by glucose transporter 1 (GLUT1) is the rate-limiting step for glucose uptake, making it a potential cancer therapeutic target. However, GLUT1 is widely expressed and performs crucial functions in a variety of cells, and its indiscriminate inhibition will cause serious side effects.

A bubble-enhanced lanthanide-doped up/down-conversion platform with tumor microenvironment response for dual-modal photoacoustic and near-infrared-II fluorescence imaging.

As an important tumor diagnosis strategy in precision medicine, multimodal imaging has been widely studied. However, the weak imaging signal with low spatial resolution and the constant signal of lack of specific activation severely limit its disease diagnosis. Herein, a bubble-enhanced lanthanide-based up/down-conversion platform with tumor microenvironment response for dual-mode imaging, LDNP@DMSN-Au@CaCO nanoparticles (named as LDAC NPs) were successfully developed.

Organic Species-Intercalated Vanadium Oxide for Sodium-Ion Battery: Mixed-Anion Coordination Effect, Enhanced - Orbital Hybridization, and Topotactic Phase Conversion Induced by N-Substitution.

Sodium-ion battery (SIB) is a reasonable alternative to lithium-ion battery (LIB) in the field of grid-scale energy storage systems. Unfortunately, the development of appropriate cathode material is a bottleneck in the field of SIB. In the present work, (-TQ)-VO, formulated as (-TQ)VO·0.

Numerical Investigation on the Effects of Grain Size and Grinding Depth on Nano-Grinding of Cadmium Telluride Using Molecular Dynamics Simulation.

Cadmium telluride (CdTe) is known as an important semiconductor material with favorable physical properties. However, as a soft-brittle material, the fabrication of high-quality surfaces on CdTe is quite challenging. To improve the fundamental understanding of the nanoscale deformation mechanisms of CdTe, in this paper, MD simulation was performed to explore the nano-grinding process of CdTe with consideration of the effects of grain size and grinding depth.

Revealing the Mutually Enhanced Mechanism of Necroptosis and Immunotherapy Induced by Defect Engineering and Piezoelectric Effect.

Owing to low immunogenicity-induced immune escape and short-term circulating immune responses, the efficiency of immunotherapy is unsatisfactory. Therefore, triggering immunogenic cell death and establishing a long-term, mutually reinforced treatment modality are urgent challenges. In this study, ultrathin CaBi Nb O nanosheets with tunable oxygen vacancies (abbreviated as CBNO-OV1) are prepared for synergistic necroptosis and immunotherapy.

Acute Social Stress Influences Moral Decision-Making Under Different Social Distances in Young Healthy Men.

Acute social stress has been shown to influence social decision-making. This study aimed to examine how social distance modulates the influence of acute social stress on young male moral decision-making. Sixty healthy male college students were randomly divided to be exposed to the Trier Social Stress Test (TSST) or a placebo version of the TSST (P-TSST) before they performed moral decision-making tasks.

Corrigendum: A minimally manipulated preservation and virus inactivation method for amnion/chorion.

[This corrects the article DOI: 10.3389/fbioe.2022.

Application of a biodegradable poly(butylene adipate--terephthalate) membrane for phenol pervaporation recovery.

In the field of membrane separation, the environmental concerns caused by spent membranes are becoming increasingly serious, which contradicts the concept of sustainable development. Based on this, a biodegradable poly(butylene adipate--terephthalate) (PBAT) membrane was used for the first time in the pervaporation separation of phenol, a high boiling point organic compound (HBOC). By using the PBAT membrane, outstanding separation efficiency was achieved, and environmental pollution and disposal issues were also avoided.

Pollen self-elimination CRISPR-Cas genome editing prevents transgenic pollen dispersal in maize.

This study reports the development of a programmed pollen self-elimination CRISPR-Cas (PSEC) system in which the pollen is infertile when PSEC is present in haploid pollen. PSEC can be inherited through the female gametophyte and retains genome editing activity in vivo across generations. This system could greatly alleviate serious concerns about the widespread diffusion of genetically modified (GM) elements into natural and agricultural environments via outcrossing.

An approach for linear optical phase demodulation using a single photodetector.

In this paper, we propose and experimentally verify a phase-modulated radio-over-fiber (RoF) link capable of transmitting the radio frequency (RF) signal linearly. By executing the Kramers-Kronig (KK) algorithm at the receiver, the proposed link can accomplish linear optical phase demodulation with a single photodetector rather than a coherent receiver. In the 16-quadrature amplitude modulation (16-QAM) and 64-QAM microwave vector signal transmission experiments, measured error vector magnitudes (EVMs) are 4.

Are you more risk-seeking when helping others? Effects of situational urgency and peer presence on prosocial risky behavior.

Introduction: Prosocial risky behavior (PRB) proposes that individuals take risks for others' benefits or social welfare, and that this may involve trade-offs between risk and social preferences. However, little is known about the underlying cognitive mechanisms of risk-seeking or aversion during PRB.

Methods: This study adopted the dilemma-priming paradigm to examine the interaction between the risk levels of personal cost and situational urgency on PRB (Experiment 1,   = 88), and it further uncovered the modulation of the risk levels of failure (Experiment 2,   = 65) and peer presence (Experiment 3,   = 80) when helping others.

Mitochondrion-targeting and in situ photocontrolled protein delivery via photocages.

Defects in mitochondrial proteostasis contribute to many disorders, including cancer, neurodegeneration, and metabolic and genetic diseases. A strategy aimed at restoring the damaged mitochondrial proteostasis is the mitochondrion-targeting and carrier-free delivery of exogenous functional proteins that can replace the endogenous dysfunctional proteins. The modification of a protein with a photolabile protecting group (PPG, i.

Parental Attachment and Adolescent Moral Reaction Modes: The Serial Mediating Model of the Teacher-Student Relationship and Deviant Peer Affiliation.

Purpose: Moral decision outcomes and emotional experiences after moral decisions are combined to create four moral reaction modes: happy victimizer (HV), unhappy victimizer (UHV), happy moralist (HM), and unhappy moralist (UHM). This study aimed to explore the relationships between parental attachment (PA) and adolescent moral reaction modes, and further examine the mechanism of the serial mediating effects of the teacher-student relationship (TS) and deviant peer affiliation (DP).

Sample And Method: A cross-sectional study was conducted in 2022 among 3053 students (including 1496 females) from four middle schools, four high schools, and three colleges in China using a voluntary and anonymous questionnaire.

Modification of spinel MnCoO nanowire with NiFe-layered double hydroxide nanoflakes for stable seawater oxidation.

Currently, direct electrolysis of seawater-based electrolytes rather than fresh water based ones for hydrogen production is gaining more and more attentions for creating a sustainable society. However, using seawater remains more challenges owing to the existence of competitive reactions between chlorine evolution reaction (ClER) or hypochlorite generation reaction and oxygen evolution reaction (OER) and electrode erosion. In this study, a MnCoO nanowire coated with NiFe-Layered Double Hydroxide (NiFe-LDH) layer (MnCoO@NiFe-LDH) composite electrocatalyst prepared by a simple two-step hydrothermal method was applied for the seawater electrolysis, which exhibited low overpotentials of 219 and 245 mV at a relatively high current density of 100 mA cm in alkaline simulated and natural seawaters, respectively, as the anode electrocatalyst.