Publications by authors named "Changle Li"

The advancement of scattering-based single-particle tracking (S-SPT) has revolutionized label-free detection and characterization of nanoscopic objects, promising diverse analytical applications. Nevertheless, its widespread adoption has been impeded by the high technical demands on optical systems. The most promising solution involves on-chip light-scattering enhancement, but the existing field-enhancement technology fails, primarily due to their highly localized field is insufficient to cover the trajectory of particles within the interrogation time.

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Chondroid syringoma, a mixed tumor of the skin, is an acquired hamartoma that differentiates into hair follicles, sebaceous glands, and apocrine sweat glands. Chondroid syringoma in the ear region is exceptionally rare. However, we present 2 cases of ear chondroid syringoma: 1 involving multiple lesions in the external auditory canal and the other including a single lesion behind the auricle.

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Poor Self-Rated Health (SRHp) is part of a four-item scale for self-assessment. SRH from the 2019 Behavioral Risk Factor Surveillance Survey (BRFSS) is used to test hypotheses linking population-level well-being influenced by bereavement due to the death of a close friend or relative. By linking the prevalence rates of population-level well-being with exposure to bereavement, we extend our knowledge of this exposure beyond single-person studies.

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Enabling a robot to learn skills from a human and adapt to different task scenarios will enable the use of robots in manufacturing to improve efficiency. Movement Primitives (MPs) are prominent tools for encoding skills. This paper investigates how to learn MPs from a small number of human demonstrations and adapt to different task constraints, including waypoints, joint limits, virtual walls, and obstacles.

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This article introduces a novel perspective on designing a stepping controller for bipedal robots. Typically, designing a state-feedback controller to stabilize a bipedal robot to a periodic orbit of step-to-step (S2S) dynamics based on a reduced-order model (ROM) can achieve stable walking. However, the model discrepancies between the ROM and the full-order dynamic system are often ignored.

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The polymerization-induced colloid aggregation (PICA) method is commonly used to create SiO@SiO core-shell silica microspheres (CSSMs), but it often encounters challenges such as incomplete shell coating and poor reproducibility. In this paper, the formation mechanism of the silica shell layer during the preparation of SiO@SiO CSSMs using the PICA method was investigated. It was found that ureido modification can reduce the Zeta potential of the silica core surface, facilitating the deposition of coacervates formed by urea-formaldehyde resin (UF) and silica nanoparticles on the silica core surface to form the SiO shell layer when the Zeta potential of the surface is in the range of -20.

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Article Synopsis
  • Elaeagnus mollis is identified as a valuable woody oil plant due to its seeds containing high levels of lipids and vitamin E, though the mechanisms for synthesizing these components are not fully understood.
  • A chromosome-level reference genome for E. mollis has been created, revealing 36,796 protein-coding sequences and suggesting two significant whole genome duplication events in its evolutionary history.
  • The study also highlights the identification of key genes related to high lipid and vitamin E content in E. mollis seeds, providing foundational knowledge for better utilization of these resources and exploration of genetic potentials.
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Article Synopsis
  • * A study in Guangzhou, Southern China, collected rodent samples to analyze RBoV presence, finding 54 positive samples out of 296, and recovering 12 near-complete genome sequences.
  • * Phylogenetic analysis showed distinct lineages of RBoV and identified six recombination events, suggesting high genetic diversity and underscoring the need for ongoing surveillance to understand RBoV's epidemiology and potential zoonotic risks.
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Fluorescence-image guided surgery (FGS) can intraoperatively provide real-time visualization of a tumor incisal edge and high-resolution identification of tumor foci to improve treatment outcomes. In this contribution, we report a fluorescent probe NB-TAM based on intramolecularly folded photoinduced electron transfer (PET), which displayed a prominent turn-on response in the near-infrared (NIR) window upon specific interaction with the estrogen receptor (ER). Significantly, NB-TAM could delineate a clear tumor incisal edge (tumor-to-normal tissue ratio > 5) in a 70-min time window, and was successfully used to guide the facile and precise resection of ER+ breast tumors in mice.

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An experimental validation of a robotic system for radioactive iodine-125 seed implantation (RISI) in tumor treatment was conducted using customized phantom models and animal models simulating liver and lung lesions. The robotic system, consisting of planning, navigation, and implantation modules, was employed to implant dummy radioactive seeds into the models. Fiducial markers were used for target localization.

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To clarify the impact of the structure and function of soil microbial communities in the stage of abandoned farmland, three different stages of land abandoned in desert oasis areas were selected as the research objects. We used metagenomic sequencing technology to research soil microbial community structure and functional diversity characteristics of different stages of abandoned farmland. The results showed that there were significant differences in the relative abundance of the dominant phyla Actinobacteria, Proteobacteria, and Gemmatimonadetes in the soil of the three stages of returning farmland.

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Objective: This study was conducted to identify the factors (especially parental involvement, academic self-efficacy, and depression) associated with academic performance among Chinese K-12 students during the COVID-19 pandemic.

Methods: This cross-sectional study used data from the 2020 China Family Panel Studies (CFPS). The CFPS was conducted from July to December 2020 during the COVID-19 pandemic.

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Palmitoylation, which is mediated by protein acyltransferase (PAT) and performs important biological functions, is the only reversible lipid modification in organism. To study the effect of protein palmitoylation on hypopharyngeal squamous cell carcinoma (HPSCC), the expression levels of 23 PATs in tumor tissues of 8 HPSCC patients were determined, and high mRNA and protein levels of DHHC9 and DHHC15 were found. Subsequently, we investigated the effect of 2-bromopalmitate (2BP), a small-molecular inhibitor of protein palmitoylation, on the behavior of Fadu cells in vitro (50 μM) and in nude mouse xenograft models (50 μmol/kg), and found that 2BP suppressed the proliferation, invasion, and migration of Fadu cells without increasing cell apoptosis.

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Background: The Chinese central government launched the third phase of health system reforms in 2009. After a decade since the initiation of the reform, the health system has witnessed noteworthy gains. However, there is no concurrent improvement in public satisfaction with the health system.

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Purpose: Medical care delay or avoidance increases morbidity and mortality risk and is costly for the national healthcare system. The objective of this study was to identify factors associated with medical care delay or avoidance among Chinese adults during the COVID-19 pandemic.

Materials And Methods: A cross-sectional analysis was conducted using data from the 2020 China Family Panel Study (CFPS).

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Introduction: Understanding the factors that affected academic performance of students during the COVID-19 pandemic will help design effective interventions for improving students' academic performance during emergency situations as well as during regular academic environment. This cross-sectional study aimed to identify the factors that explain academic performance of students in China during the pandemic.

Methods: Data on college students from the 2020 China Family Panel Studies were used, and the final sample consisted of 728 students.

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Background: Although the tobacco epidemic is one of the greatest public health threats, the smoking cessation rate among Chinese adults is considerably lower. Personality information may indicate which treatments or interventions are more likely to be effective. China is the largest producer and consumer of tobacco worldwide.

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Canine circovirus (CanineCV) is a single-stranded DNA virus that circulates in dogs and wild carnivores around the world. It has been suggested to be associated with diseases of respiratory and gastrointestinal systems, though its pathogenic potential remains unclear. Currently, CanineCV is divided into six genotypes (genotype 1-6), and genotypes 2, 3, and 4 have been described in China.

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Background: The Behavioral Risk Factor Surveillance System (BRFSS) is an annual survey designed to identify trends in the public's health. In its 2019 field survey, the U.S.

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Background: Binge drinking is a pattern of alcohol abuse. Its prevalence and associated risk factors are not well documented. Heavy drinking, on the other hand, has a well-documented association with bereavement.

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Unlabelled: Codon usage bias (CUB) reveals the characteristics of species and can be utilized to understand their evolutionary relationship, increase the target genes' expression in the heterologous receptor plants, and further provide theoretic assistance for correlative study on molecular biology and genetic breeding. The chief aim of this work was to analyze the CUB in chloroplast (cp.) genes in nine species to provide references for subsequent studies.

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Rationale: Public trust in physicians had declined in China for decades before the COVID-19 pandemic. During the COVID-19 pandemic, frontline physicians have experienced high work volume despite a high risk of COVID-19 infection. The willingness of physicians to treat COVID patients with a high risk of exposure to the infection may have improved public trust in physicians.

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Lithium-ion capacitors (LICs) have drawn increasing attention, due to their appealing potential for bridging the performance gap between lithium-ion batteries and supercapacitors. Especially, dual-carbon lithium-ion capacitors (DC-LICs) are even more attractive because of the low cost, high conductivity, and tunable nanostructure/surface chemistry/composition, as well as excellent chemical/electrochemical stability of carbon materials. Based on the well-matched capacity and rate between the cathode and anode, DC-LICs show superior electrochemical performances over traditional LICs and are considered to be one of the most promising alternatives to the current energy storage devices.

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Introduction: The high co-occurrence of tobacco smoking and depression is a major public health concern during the novel coronavirus disease-2019 pandemic. However, no studies have dealt with missing values when assessing depression. Therefore, the present study aimed to examine the effect of tobacco smoking on depressive symptoms using a multiple imputation technique.

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Background: Trust between the parties is essential for the efficient functioning of the healthcare market. Physician-patient relationship represents an asymmetric information situation and trust in physicians is critical for improving health and wellbeing of patients. In China, trust in physicians appears to be quite low creating conflicts between physicians and patients.

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Synopsis of recent research by authors named "Changle Li"

  • - Changle Li's research encompasses a diverse range of topics including plant genome evolution and biosynthesis mechanisms, particularly focusing on Elaeagnus mollis, a valuable oil plant useful for lipid and vitamin E production.
  • - His studies also explore public health issues, such as the epidemiology of bocavirus in urban rodents, medical care delays during the COVID-19 pandemic, and factors influencing academic performance among Chinese students during the pandemic.
  • - Furthermore, his work extends to innovative medical applications, revealing advancements in fluorescence-image guided surgery for breast tumors and validating robotic-assisted techniques for tumor treatment, demonstrating a strong integration of biology and technology in addressing health-related challenges.

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