siRNA Nanoparticle Dry Powder Formulation with High Transfection Efficiency and Pulmonary Deposition for Acute Lung Injury Treatment.

Acute lung injury (ALI) is a severe inflammatory syndrome, which was caused by diverse factors. The COVID-19 pandemic has resulted in a higher mortality rate of these conditions. Currently, effective treatments are lacking.

Simultaneous Determination of Three Flavonoids in Rat Plasma of Masson Pinus Needles (Pinus massoniana L.) Extracts by UHPLC-MS/MS and Application to Pharmacokinetics Studies after Oral and Transdermal Administration.

Pinus massoniana needles, a traditional herb, were applied to prevent hair loss in China. Studies available mainly focused on pine needle flavonoids with various biological activities. However, there has been no pharmacokinetics study of the flavonoids from Pinus needles extract.

Fibroblast growth factor 21 attenuates the progression of hyperuricemic nephropathy through inhibiting inflammation, fibrosis and oxidative stress.

Elevated levels of circulating fibroblast growth factor 21 (FGF21) have been reported in patients with hyperuricemia. However, the effect of FGF21 in hyperuricemic nephropathy (HN) remains unexplored. Here, we investigated the effect and mechanism of action of FGF21 on HN.

Recursive Copy and Paste GAN: Face Hallucination From Shaded Thumbnails.

Existing face hallucination methods based on convolutional neural networks (CNNs) have achieved impressive performance on low-resolution (LR) faces in a normal illumination condition. However, their performance degrades dramatically when LR faces are captured in non-uniform illumination conditions. This paper proposes a Recursive Copy and Paste Generative Adversarial Network (Re-CPGAN) to recover authentic high-resolution (HR) face images while compensating for non-uniform illumination.

Efficient high-solids enzymatic hydrolysis of corncobs by an acidic pretreatment and a fed-batch feeding mode.

Corncob is an abundant and renewable resource that could be enzymatically hydrolyzed to fermentable sugar. A major impediment in corncob utilization is the low hydrolysis efficiency at high-solids content. This study attempted different pretreatment methods and fed-batch modes to achieve a 25% solids content hydrolysis with high yields.

Characterization of antimicrobial activity of three strains isolated from Chinese traditional dairy food.

Many strains can secrete some antimicrobial substances and be added to food as antimicrobial agents and preservatives. In this study, three strains (P1, S11, and M7) with strong antimicrobial activity against three pathogenic bacteria were isolated from Xinjiang traditional dairy products. Five common organic acids produced by fermentation of strains play a key role in inhibiting three pathogenic bacteria.

Single Sample Face Recognition under Varying Illumination via QRCP Decomposition.

In this paper, we present a novel high-frequency facial feature and a high-frequency based sparse representation classification to tackle single sample face recognition (SSFR) under varying illumination. Firstly, we propose the assumption that QRCP bases can represent intrinsic face surface features with different frequencies, and their corresponding energy coefficients describe illumination intensities. Based on this assumption, we take QRCP bases with corresponding weighting coefficients (i.

A near-threshold, 0.16 nJ/b OOK-transmitter with 0.18 nJ/b noise-cancelling super-regenerative receiver for the medical implant communications service.

A 0.16 nJ/b MICS transmitter and 0.18 nJ/b super-regenerative receiver are demonstrated, where each is specifically designed to operate in the near-threshold region.

[Study on distribution characteristics and potential ecological risk of soil heavy metals in the Yellow River beach region in Kaifeng City].

The distributions, soil environment status and potential ecological risk of heavy metals were studied in beach soil of returning the cropland into Yellow River beach region in Kaifeng by the Nemerows and Håkansons methods. The results showed that (1) as Among the average contents of the five heavy metals Pb, Cr, Hg, As and Cd, the highest was the average content of Cr, and the lowest was the average content of Pb and Hg. In addition to Hg, the coefficients of variation of other heavy metals were relatively small, indicating that the content of heavy metals was quite different at different sites, and to some extent, relecting that Hg, As and Pb were the major elements polluting the soil, among which, Pb pollution was the pollution with universality.

A one-dimensional heterometallic coordination polymer with a three-dimensional supramolecular framework: poly[μ2-aqua-diaqua(2,2'-bipyridyl)(μ5-2-sulfonatobutanedioato)copper(II)sodium(I)].

The title compound, [CuNa(C(4)H(3)O(7)S)(C(10)H(8)N(2))(H(2)O)(3)](n), consists of one Cu(II) cation, one Na(I) cation, one 2-sulfonatobutanedioate trianion (SSC(3-)), one 2,2'-bipyridyl (bpy) ligand and three coordinated water molecules as the building unit. The coordination of the Cu(II) cation is composed of two pyridyl N atoms, one water O atom and two carboxylate O atoms in a distorted square-pyramidal coordination geometry with an axial elongation. The Na(I) cation is six-coordinated by three water molecules and three carboxylate O atoms from three SSC(3-) ligands in a distorted octahedral geometry.