Publications by authors named "Changhua Jing"
Article Synopsis
- Multiple myeloma (MM) is a serious blood cancer with an increasing patient population, and the role of Zinc finger protein 655 (ZNF655) in its progression is not well understood.
- This study examined how decreasing ZNF655 levels affected MM cell traits and tumor growth, using various lab techniques to measure changes in cell behavior.
- The results showed that reducing ZNF655 significantly decreased MM cell growth, halted the cell cycle, and triggered cell death, suggesting that targeting ZNF655 may offer a new way to treat MM through its effects on AKT activation.
This study focuses on clarifying the regulation of chicken 14-3-3σ protein on the fibrous histiocyte proliferation caused by ALV-J-SD1005 strain infection. DF-1 cells were inoculated with 10 TCID of ALV-J-SD1005 strain; the cell proliferation viability was dramatically increased and 14-3-3σ expressions were dramatically decreased within 48 h after inoculation. Chicken over-expression could significantly decrease the cell proliferation and the ratio of S-phase cells, but increase the ratio of G2/M-phase cells in ALV-J-infected DF-1 cells; by contrast, chicken knockdown expression could cause the opposite effects.
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