Publications by authors named "Changheng Yang"

Objective: CIDEB (Cell death-inducing DNA fragmentation factor alpha-like effector B), a family member of CIDEs (Cell death-inducing DFF45-like effectors), is well known as a crucial regulator for lipid metabolic signaling pathways in various metabolic tissues and secretory glands. However, its role in regulating intramuscular fat (IMF) deposition in goat remains unclear.

Methods: The expression vector pcDNA3.

View Article and Find Full Text PDF

Endothelial lipase (LIPG), a member of the triglyceride lipase family, plays an essential role in human diseases and lipid metabolism. However, its function in goat intramuscular fat (IMF) deposition remains unclear. In this study, we investigated the role of the LIPG gene in IMF deposition by knocking down and overexpressing it in goat intramuscular preadipocytes.

View Article and Find Full Text PDF

Malonyl-CoA decarboxylase () is a major regulator of fatty acid oxidation catalyzing the decarboxylation of malonyl coenzyme A (malonyl-CoA). Although its involvement in human diseases has been well studied, its role in intramuscular fat (IMF) deposition remains unknown. In this present study, 1726 bp of cDNA was cloned (OM937122) from goat liver, including 5'UTR of 27 bp, 3'UTR of 199 bp, and CDS of 1500 bp, encoding 499 amino acids.

View Article and Find Full Text PDF

Diacylglycerol acyltransferase 2 (DGAT2) is the key enzyme that catalyzes the last step of triglyceride synthesis. However, its role in intramuscular fat (IMF) deposition in goat remains unclear. The purpose of this study was to explore the role of DGAT2 in regulating goat IMF deposition.

View Article and Find Full Text PDF

Low-cost, low power consumption gas sensors that can detect or quantify various gas analytes are of increasing interest for various applications ranging from mobile health, to environmental exposure assessment and homeland security. In particular miniature gas sensors based on nanomaterials that can be manufactured in the form of sensor arrays present great potential for the development of portable monitoring devices. In this study, we demonstrate that a chemiresistive nanosensor comprised of single walled carbon nanotubes decorated with gold nanoparticles has impressive sensitivity to elemental mercury (Hg) gas concentrations, with a lower detection limit as low as 2 ppb(v).

View Article and Find Full Text PDF