Publications by authors named "Changfang Luo"
Article Synopsis
- Early-life malnutrition, particularly from famine exposure, significantly increases the risk of developing renal impairment later in life, as shown by a meta-analysis of twelve observational studies.
- The analysis revealed that prenatal famine exposure is linked to a higher likelihood of chronic kidney disease (CKD), reduced estimated glomerular filtration rate (eGFR), and elevated serum creatinine levels, compared to those not exposed.
- Although famine exposure in childhood impacts renal function, the link to CKD isn't as strong, and the overall evidence quality is low, suggesting potential age-related confounding factors.
Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, inflammation and fibrosis play an important role in its progression. Histone lysine crotonylation (Kcr) was first identified as a new type of post-translational modification in 2011. In recent years, prominent progress has been made in the study of sodium crotonate (NaCr) and histone Kcr in kidney diseases.
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