Publications by authors named "Change Zhu"

Objectives: To investigate the relationship between sleep and multimorbidity, including the associations between sleep duration and multimorbidity, as well as between sleep quality and multimorbidity.

Methods: Using data from the three latest waves of the Chinese Longitudinal Health Longevity Study (2011, 2014, and 2018), a binary panel regression was conducted to investigate the quadratic relationship between sleep duration and multimorbidity. Subsequently, quadratic fitting and robustness analysis were further utilized to strengthen the verification of this relationship.

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Article Synopsis
  • - Previous studies showed a link between mechanical power (MP) and lung injury, but this research specifically looks at its effects on postoperative pulmonary complications (PPCs) in kids during one-lung ventilation (OLV) and found limited evidence on the topic.
  • - The study involved 581 children aged 2 years or younger who underwent video-assisted thoracic surgery (VATS), exploring the incidence of PPCs with a focus on different MP levels, showing no significant association between MP and reduced PPCs.
  • - Findings indicated that factors like male gender, longer OLV duration, less experienced surgeons, and lower positive end-expiratory pressure (PEEP) were linked to higher rates of PPCs within a week after surgery
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Article Synopsis
  • * A search of peer-reviewed articles identified fifteen relevant papers, highlighting five main barriers: cultural beliefs, language issues, structural factors, health literacy, and social/economic challenges.
  • * The findings indicate a need for more culturally and linguistically sensitive education and support systems to improve healthcare access for older Chinese immigrants and other ethnic groups.
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Background: Postoperative pulmonary complications (PPCs) are associated with high mortality and morbidity rates. Children are more susceptible to PPCs owing to smaller functional residual capacity and greater closing volume. Risk factors of PPCs in children undergoing lung resection remain unclear.

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Background: Children are more susceptible to postoperative pulmonary complications (PPCs) due to their smaller functional residual capacity and higher closing volume; however, lung-protective ventilation (LPV) in children requiring one-lung ventilation (OLV) has been relatively underexplored.

Objectives: To evaluate the effects of LPV and driving pressure-guided ventilation on PPCs in children with OLV.

Design: Randomised, controlled, double-blind study.

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Purpose: To explore the impact of unmet community service demands on loneliness among older adults.

Methods: Based on the longitudinal tracking data of CLHLS (2008-2018), latent growth curve model (LGCM) was used to describe the trajectory of loneliness among older adults. Panel regression was used to analyze the impact of unmet community service demands on loneliness, and latent classification analysis (LCA) was used to classify the older adults and analyze the differences in loneliness among different types of older adults.

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Article Synopsis
  • Bronchial blocker balloons, when inflated with small air volumes, pose risks of airway injuries in young children, necessitating better guidelines for safe usage.
  • The study assessed the necessary air volumes for these balloons in 79 pediatric patients undergoing thoracoscopic surgery, measuring balloon pressure and bronchial diameters to determine optimal occlusion.
  • Results indicated that occluding the left mainstem bronchus required less than 1 mL of air without injury risk, while the right required 1.3 mL; overall, high-quality lung isolation was achieved with minimal complications.
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Background: This study aimed to explore the association between health status (physical, mental, and self-rated health) and multidimensional poverty (subjective and objective poverty) in older adults.

Method: A panel binary logit regression approach was applied to four waves of CLHLS data (2008, 2011, 2014, and 2018). In total,1,445 individuals were included after data cleaning.

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Article Synopsis
  • - The study develops an evolutionary game model involving hospitals, third-party entities, and the Chinese government to analyze strategies for tackling healthcare fraud using a reward and punishment system.
  • - Key findings indicate that increasing fines on hospitals encourages compliance, while a lack of incentives for third parties leads to ineffective investigations.
  • - The research also reveals that while higher government rewards can enhance local supervision, the associated costs may hinder effective oversight.
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Objectives: to examine the causal relationship between sleep quality and life satisfaction and explore the mediating role of health status on the relationship between sleep quality and life satisfaction.

Methods: A total of 1856 older Chinese people participating in 2011, 2014, and 2018 waves of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) were included. A cross-lagged panel analysis (CLPA) combined with mediator analysis was utilized.

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This study aimed to research the trajectory of leisure activity and the health status of older adults and analyze the effects of leisure activity on the health status of older adults. Based on the longitudinal data of CLHLS (2008-2018), the latent growth curve model (LGCM) was used; we found that the leisure activities (LA), activities of daily living (ADL) ability, instrumental activities of daily living (IADL) ability, and cognitive ability (COG) of older adults show a nonlinear downward trend over time. Furthermore, the panel binary regression analysis is used to find that leisure activities have significant inhibitory effects on ADL disorder, IADL disorder, and cognitive impairment in the older population.

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Based on the data of four periods of CLHLS (2008, 2011, 2014, 2018), the latent variable growth model (LGCM) was applied to 2344 older adults who completed four follow-up surveys, to study the trajectory of leisure activities and cognitive ability and explore the relationship between leisure activities and cognitive ability of older adults. The results showed that: (1) leisure activities and cognitive ability of older adults showed a non-linear downward trend; (2) leisure activities significantly and positively predicted the cognitive ability of older adults at every time point; (3) the initial level of leisure activity positively predicted the initial level of cognitive ability but negatively predicted the rate of cognitive decline; In addition, cognitive activities had a greater effect on cognitive ability than non-exercise physical activities; (4) the rate of decline of leisure activities also significantly and positively predicted the rate of decline of cognitive ability; (5) cross-lagged regression analysis further suggested the overall positive predictive effect of leisure activity on cognitive ability; (6) overall, education level had a significant contribution to cognitive ability, and the higher the education level, the slower the decline of cognitive ability; and (7) smoking could promote cognitive ability in older adults and no significant effect was found between alcohol drinking and cognitive ability. Accordingly, the government should encourage older adults to do more leisure activities, especially the cognitive activity, to effectively prevent cognitive decline.

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Article Synopsis
  • The study aimed to compare the effects of two ventilation methods—pressure controlled volume guaranteed (PCV-VG) and volume controlled ventilation (VCV)—in children undergoing one lung ventilation during lung surgery.
  • A total of 63 patients were randomly assigned to either PCV-VG or VCV; results showed that the PCV-VG group had significantly lower peak inspiratory pressures (PIP) and higher static compliance compared to the VCV group throughout various stages of the procedure.
  • Although both groups saw improvement in lung aeration postoperatively, there were no significant differences in other outcomes like complications or length of hospital stay, suggesting that while PCV-VG had some advantages, overall effects on post-surgery recovery were
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The imbalance of mitochondrial dynamics plays an important role in the pathogenesis of cerebral ischemia/reperfusion (I/R) injury. Zinc-finger protein 36 (ZFP36) has been documented to have neuroprotective effects, however, whether ZFP36 is involved in the regulation of neuronal survival during cerebral I/R injury remains unknown. In this study, we found that the transcriptional and translational levels of ZFP36 were increased in immortalized hippocampal HT22 neuronal cells after oxygen-glucose deprivation/reoxygenation (OGD/R) treatment.

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Background: Atelectasis is a common postoperative complication. Peri-operative lung protection can reduce atelectasis; however, it is not clear whether this persists into the postoperative period.

Objective: To evaluate to what extent lung-protective ventilation reduces peri-operative atelectasis in children undergoing nonabdominal surgery.

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Background And Objectives: is commonly used for children undergoing hypospadias repair. However, the safety of caudal block for hypospadias repair in children is controversial in terms of surgical complications such as urethrocutaneous fistula and glans dehiscence. We sought to perform a meta-analysis to estimate the analgesic efficacy and relative complications of caudal block for hypospadias repair in children.

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Background: Dexamethasone has become a popular additive for regional anesthesia. The aim of this meta-analysis was to assess the effectiveness of this additive on the duration of postoperative analgesia, postoperative vomiting, and possible adverse events in pediatrics.

Methods: We searched databases, conference records, and registered trials for randomized controlled trials.

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Objective: To evaluate the effectiveness and safety of transcranial direct current stimulation for fibro-myalgia.

Methods: Databases, conference records and registered trials were searched for articles published from the date of establishment of the database through to October 2015. Six randomized controlled trials (n=192) of transcranial direct current stimulation for fibromyalgia were included in the current study.

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