Publications by authors named "Changdong Li"

Article Synopsis
  • Mitochondrial oxidative stress is a problem that happens after a brain injury called intracerebral hemorrhage (ICH), and it can cause brain cells to die.
  • Celastrol is a natural substance that helps protect the brain and has been shown to improve brain function and reduce damage after ICH.
  • The study found that celastrol works better when a protein called OPA1 is present, which helps keep the mitochondria (the powerhouses of the cell) healthy and working properly after a brain injury.
View Article and Find Full Text PDF

Beta zeolites have been widely used in acid-catalyzed reactions because of their excellent properties. An in-depth study of the position, quantity, and distribution of beta zeolites substituted by Al is significant to understand the catalytic performance of the active site of zeolite catalysts. The distribution of Al in H-BEA and the structure of silanol nests in dealuminated BEA at different Si/Al ratios and synthesis temperatures were studied by the DFT method.

View Article and Find Full Text PDF

Backgrounds: Pregnancy termination during the second trimester in patients with placenta previa and placenta accreta spectrum (PAS) is a complex and challenging clinical problem. Based on our literature review, there has been a relative increase in the number of such cases being treated by hysterotomy and/or local uterine lesion resection and repair. In the present study, a retrospective analysis was conducted to compare the clinical outcomes when different management strategies were used to terminate pregnancy in the patients with placenta previa and PAS.

View Article and Find Full Text PDF

Landslide displacement monitoring plays a fundamental role in the study of landslide evolution mechanisms, forecasting, risk assessment, prevention, and control. To fill the deficiencies of traditional instrumentation for measuring landslide displacement distributed along lateral direction, a landslide displacement measurement method based on deformation-coupled pipeline trajectory measurement is proposed, and a pipeline trajectory inertial measurement instrument is developed. The developed instrument, primarily comprised of a single shaft gyro, two axis accelerometers, and an external roller encoder, is designed as an axial half strapdown-radial half platform structure combined with a mechanical gravity platform.

View Article and Find Full Text PDF

The aim of this study was to investigate early clinical features and risk factors for cesarean scar pregnancy (CSP). Study group of 206 CSP patients out of 6853 women with early pregnancies, diagnosed from 2014 to 2016 was compared with a randomly selected control group of 412 patients. Early clinical features for CSP were vaginal bleeding (OR: 9.

View Article and Find Full Text PDF

Objective: To investigate the effects of isoliquiritigenin on the migration and invasion of human glioma stem cells and the underlying mechanism.

Methods: The stem cell markers CD133 and Nestin in SHG44 human glioma stem cells were examined with immunofluorescence microscopy. The migration and invasion ability of glioma stem cells was determined by transwell method.

View Article and Find Full Text PDF

The physical model test of landslides is important for studying landslide structural damage, and parameter measurement is key in this process. To meet the measurement requirements for deep displacement in landslide physical models, an automatic flexible inclinometer probe with good coupling and large deformation capacity was designed. The flexible inclinometer probe consists of several gravity acceleration sensing units that are protected and positioned by silicon encapsulation, all the units are connected to a 485-comunication bus.

View Article and Find Full Text PDF

Objective: To estimate the association between uterine fibroids and adverse obstetric outcomes.

Methods: This was a retrospective cross-sectional study of 112,403 deliveries from 14 provinces and 39 different hospitals in 2011 in mainland China. We compared pregnancy outcomes in women with and without uterine fibroids who underwent detailed second trimester obstetric ultrasonography during 18 to 22 weeks.

View Article and Find Full Text PDF

In the present study, we evaluated the diagnosis and management modalities of caesarean scar pregnancy (CSP). Thirty patients diagnosed with CSP were retrospectively studied between February, 2010 and February, 2012. Twenty-five patients were offered prophylactic uterine artery embolization (UAE) and methotrexate (MTX) prior to uterine suction curettage.

View Article and Find Full Text PDF

Scanline observation is known to introduce an angular bias into the probability distribution of orientation in three-dimensional space. In this paper, numerical solutions expressing the functional relationship between the scanline-observational distribution (in one-dimensional space) and the inherent distribution (in three-dimensional space) are derived using probability theory and calculus under the independence hypothesis of dip direction and dip angle. Based on these solutions, a novel method for obtaining the inherent distribution (also for correcting the bias) is proposed, an approach which includes two procedures: 1) Correcting the cumulative probabilities of orientation according to the solutions, and 2) Determining the distribution of the corrected orientations using approximation methods such as the one-sample Kolmogorov-Smirnov test.

View Article and Find Full Text PDF

Cervical intraepithelial neoplasia (CIN) is a precancerous disease of cervical squamous cell carcinoma. We Used Mass Spectrometry based peptidome profile study to predict the transformation of CIN1, which is the primary stage of this lesion. .

View Article and Find Full Text PDF

Objective: To estimate cesarean delivery rates and indications by region in mainland China.

Methods: A cross sectional survey of all deliveries in 39 hospitals in 14 provinces of mainland China from January 1 to December 31, 2011 was evaluated for mode of delivery, cesarean delivery rates and indications for delivery.

Results: (1) A survey of a total of 112 138 women at delivery with gestations greater than 24 weeks was analyzed.

View Article and Find Full Text PDF

Investigation: To study the differences immune function in normal cervix, cervical intraepithelial neoplasia (CIN) and cervical cancer tissue, and study the relationship between human papillomavirus (HPV) infection and cervical local immune function.

Materials And Methods: This study determined the form, quantity, distribution, and intensity of CD4+Th cells, S-100+ dendritic cells (DCs) and CD57+NK cells in the normal cervical tissue, CIN cervical tissue, and cervical cancer by histopathological and image analyses.

Results: The immune function was differences in the progress of cancer genesis.

View Article and Find Full Text PDF

Hypertensive disorders of pregnancy (HDP) are a group of medical complications in pregnancy and also a risk factor for severe pregnancy outcomes, but it lacks a large-scale epidemiological investigation in recent years. This survey represents a multicenter cross-sectional retrospective study to estimate the prevalence and analyze the risk factors for HDP among the pregnant women who had referred for delivery between January 1st 2011 and December 31st 2011 in China Mainland. A total of 112,386 pregnant women were investigated from 38 secondary and tertiary specialized or general hospitals randomly selected across the country, of which 5,869 had HDP, accounting for 5.

View Article and Find Full Text PDF

Objective: To examine the treatment of previous cesarean delivery scar defect after cesarean delivery and the feasibility of laparoscopic uterine repair or hysteroscopic scar excision.

Study Design: A retrospective clinical study that took place from June 2009 to March 2013 and included 41 women who had previously had cesarean deliveries.

Results: Seventeen women underwent a laparoscopic approach for the repair of scar diverticula, and 24 women underwent a hysteroscopic resection of fibrotic tissue overhanging underneath the diverticula.

View Article and Find Full Text PDF

Objective: To survey the proportion of births born after assisted reproductive technology (ART) and compare the obstetric and prenatal complications between ART and spontaneous pregnancy in women in mainland China.

Design: Retrospective analysis.

Setting: Thirty-nine hospitals.

View Article and Find Full Text PDF

Objective: To employ the classical Wnt/β-catenin signaling pathway interference to explore the effects on the functional changes of eutopic endometrium stromal cells and the differences between endometriosis in a murine model.

Methods: Two out of three mouse groups received an injection of either Wnt/β-catenin signaling pathway activator or blocker. Later the endometrial tissue samples were obtained to develop endometrial stromal cell cultures for the detection of cell invasion ability via Boyden chamber invasion assay and Western blot (WB).

View Article and Find Full Text PDF

Objectives: To determine the prevalence and factors associated with histologic diagnoses of cervical intraepithelial neoplasia in women with ASC-US.

Method: Sampling investigations were carried out on married women aged 25-54 in 12 districts in Beijing from April 2007 to November 2008. Further examinations and analyses were carried out on women with ASC-US in the cytological screening.

View Article and Find Full Text PDF

Investigation: To evaluate the value of the loop electrosurgical excision procedure (LEEP) for repeat low-grade squamous intraepithelial lesions (LSIL) with unsatisfactory colposcopy and the outcomes of postconization.

Methods: We performed LEEP in 136 patients and followed them up with colposcopy, cytology, and high-risk HPV (HR-HPV) detection using Hybrid Capture II (HCII).

Results: 55.

View Article and Find Full Text PDF

Objective: to investigate high risk factors associated with cervical intraepithelial neoplasia (CIN) in married women aged 25 to 54 years in Beijing.

Methods: from Mar. 2007 to Sep.

View Article and Find Full Text PDF

Background: Few population-based studies have investigated premalignant and malignant cervical abnormalities in Beijing.

Methods: A total of 6,385 randomly selected sexually active women were interviewed and examined. Cervical lesion was diagnosed using cytology and histology.

View Article and Find Full Text PDF

Objective: To investigate prevalence of cervical intraepithelial neoplasia (CIN) among the married women aged 25-54 years in Beijing.

Methods: With method of cross sectional survey, 6339 married women at age of 25 to 54 years were selected randomly in 137 communities of 12 districts or counties in Beijing from March 2007 to September 2008. The cervical smear cytology and high-risk human papillomavirus (HPV) infection of cervical secretion were detected.

View Article and Find Full Text PDF

Objective: To investigate the characteristic of precancerous conditions of cervical intraepithelial neoplasia (CIN) and its related high-risk factors among the married women in Beijing, China.

Methods: Based upon the method of cross-sectional survey, 6339 married women at reproductive age from 25 to 54 years old were selected randomly in a total of 137 communities of 12 districts or counties in Beijing from March 2007 to September 2008. The interview was carried out with unified questionnaires and gynecological examinations.

View Article and Find Full Text PDF

Objective: To investigate the effects of ovarian carcinoma cells on the differentiation, maturation, and function of the dendritic cells (DC).

Methods: Human epithelial ovarian carcinoma cells were isolated from specimens of ovarian carcinoma from 12 patients obtained during operation, and cultured. Peripheral blood samples were collected from these patients.

View Article and Find Full Text PDF