Electroacupuncture at Zusanli regulates the pathological phenotype of inflammatory bowel disease by modulating the NLRP3 inflammasome pathway.

Background: This study sought to explore the effect of electroacupuncture (EA) intervention at Zusanli (ST36) acupoint on modulating the NLRP3 inflammasome pathway for treating inflammatory bowel disease (IBD).

Methods: C57BL/6 mice were administrated with 3% dextran sulfate sodium (DSS) to construct the IBD model. DSS mice were then administrated with EA (10 Hz, 1.

Occurrence and correlation of microplastics and dibutyl phthalate in rivers from Pearl River Delta, China.

Microplastics have been identified as the novel contaminants in various environments. Phthalates would be released from plasticized microplastics into a riverine environment while transporting to a marine region, but data on their relationship in rivers have been scarce. In this study, the occurrence, distribution and correlation of microplastics and dibutyl phthalate (DBP) in two rivers from the Pearl River Estuary were investigated.

miR-142-5p Inhibits Cell Invasion and Migration by Targeting DNMT1 in Breast Cancer.

Abnormal cell proliferation caused by abnormal transcription regulation mechanism seems to be one of the reasons for the progression of breast cancer and also the pathological basis. MicroRNA-142-5p (miR-142-5p) is a low-expressed miRNA in breast cancer. The role of MKL-1s regulation of DNMT1 in breast cancer cell proliferation and migration is still unclear.