Total and simulated keratometry measurements using IOLMaster 700 and Pentacam AXL after small incision lenticule extraction.

Purpose: Calculating the intraocular lens (IOL) in patients after corneal refractive surgery presents a challenge. Because an overestimation of corneal power in cases undergone this surgery leading to a subsequent under-correction of IOL power. However, recent advancements in technology have eliable measurement of total corneal power.

Associations of Near Work, Time Outdoors, and Sleep Duration With Myopic Regression 5 Years After SMILE and FS-LASIK: A Cross-sectional Study.

Purpose: To investigate the association of near work, time outdoors, and sleep duration with myopic regression 5 years after small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK) .

Methods: This cross-sectional study included patients who received SMILE or FS-LASIK at Beijing Tongren Hospital 5 years ago. The patients underwent ophthalmic examinations including visual acuity, intraocular pressure, subjective refraction, slit-lamp examination, keratometry, corneal topography, optical coherence tomography, and fundus examination from January 2020 to March 2023.

Association between Fundus Tessellation and Contrast Sensitivity in Myopic Eyes.

Purpose: To assess the association of fundus tessellation with contrast sensitivity, Quality of Vision questionnaire, and other factors at five years postcorneal refractive surgery.

Methods: This is a cross-sectional study. Both eyes of 98 subjects (196 eyes) who received femtosecond laser keratomileusis (FS-LASIK) or small incision lenticular extraction (SMILE) five years prior were enrolled in this study.

Performance of Bandage Contact Lens in Patients Post-ocular Surgeries: A Systematic Literature Review.

This study systematically reviewed the performance of bandage contact lenses (BCL) such as lotrafilcon A, lotrafilcon B, senofilcon A, balafilcon A, and comfilcon A as postoperative treatment in different ocular surgeries. A systematic search of English and Chinese databases (from inception to December 2021) was conducted for studies reporting the efficacy of BCLs after ocular surgeries. Postoperative symptoms, corneal healing, and visual outcomes were studied.

Comparison of total corneal power measurements obtained with different devices after myopic keratorefractive surgery.

Aim: To analyze the differences, agreements, and correlation among total corneal power parameters generated by different instruments after myopic keratorefractive surgery.

Methods: The prospective cross-sectional study included patients who underwent myopic keratorefractive surgery and received measurements of corneal power 3mo after surgery. Automated keratometer was used for the measurement of simulated keratometry (SimK), swept-source optical coherence tomography (SS-OCT) based biometer for total keratometry (TK), anterior segment-OCT for real keratometry (RK), and Scheimpflug keratometer for the true net power (TNP), the total corneal refractive power (TCRP) and equivalent K-readings (EKR).

Repeatability and agreement between a reference Scheimpflug tomographer and a low-cost Scheimpflug system.

Purpose: To assess the repeatability and agreement between Scheimpflug-based corneal topographers, Scansys and Pentacam, in measuring ocular parameters in myopic eyes.

Setting: Grade-A tertiary hospital in Beijing, China.

Design: Cross-sectional study.

Corneal biomechanical characteristics following small incision lenticule extraction for myopia and astigmatism with 3 different cap thicknesses.

Background: The design of cap thickness for small incision lenticule extraction (SMILE) plays a role in post-laser vision correction (post-LVC) corneal biomechanics. This study aimed to compare the corneal biomechanical characteristics following SMILE with different cap thicknesses of 110 μm, 120 μm, and 130 μm for myopia and myopic astigmatism correction.

Methods: Seventy-five patients (146 eyes) who underwent SMILE with designed cap thickness of 110 μm, 120 μm, and 130 μm were recruited at the Eye Center of Beijing Tongren Hospital between August 2020 and November 2021.

Clinical Feasibility and Safety of Scleral Collagen Cross-Linking by Riboflavin and Ultraviolet A in Pathological Myopia Blindness: A Pilot Study.

Introduction: To investigate the feasibility and safety of scleral ultraviolet A (UVA) cross-linking (scleral CXL) on pathologically blindness.

Methods: This was a prospective, observational clinical study. Five patients with monocular blindness due to pathological myopic maculopathy were enrolled.

Comparing Standard Keratometry and Total Keratometry Before and After Myopic Corneal Refractive Surgery With a Swept-Source OCT Biometer.

Background: More recently, the swept-source OCT biometer-IOLMaster 700 has provided direct total corneal power measurement, named total keratometry. This study aims to evaluate whether standard keratometry (SK) and total keratometry (TK) with IOLMaster 700 can accurately reflect the corneal power changes induced by myopic corneal refractive surgery.

Methods: In this study, the biometric data measured with the swept-source OCT biometer-IOLMaster 700 before and 3 months after the myopic corneal refractive surgery were recorded.

Flap-making patterns and corneal characteristics influence opaque bubble layer occurrence in femtosecond laser-assisted laser in situ keratomileusis.

Background: Opaque bubble layer (OBL), which generates from photo-disruptive procedures on the cornea, has been a common phenomenon during femtosecond laser-assisted refractive surgeries and it would potentially impact eye tracking and flap lifting. And we have observed that an updated flap-making pattern could form less OBL clinically than the traditional pattern, which needed further approval. Thus, the purpose of this study is to prove our observation and investigate the possible risk factors related to the occurrence and type of OBL in laser in situ keratomileusis (LASIK) flaps using the Visumax laser system.

Differences of Corneal Biomechanics Among Thin Normal Cornea, Forme-Fruste Keratoconus, and Cornea After SMILE.

To compare the corneal biomechanics of thin normal cornea (TNC) with thinnest corneal thickness (TCT) (≤500 µm), forme-fruste keratoconus (FFKC) and cornea after small incision lenticule extraction (Post-SMILE) had their central corneal thickness (CCT) matched by Corneal Visualization Scheimpflug Technology (Corvis ST). CCT were matched in 23 eyes with FFKC, 23 eyes by SMILE in 3 months post-operatively, and 23 TNC eyes. The differences in corneal biomechanics by Corvis ST among the three groups were compared.

Comparison of clinical outcome of small-incision lenticule intrastromal keratoplasty and FS-LASIK for correction of moderate and high hyperopia.

Aim: To compare the clinical outcome of small-incision lenticule intrastromal keratoplasty (sLIKE) and femtosecond laser-assisted keratomileusis (FS-LASIK) for correction of moderate and high hyperopia.

Methods: A case-controlled clinical study was performed. Twenty right eyes of 20 moderate and high hyperopia patients underwent sLIKE (sLIKE group) and 22 right eyes of 22 moderate and high hyperopia patients underwent FS-LASIK (FS-LASIK group) were enrolled in this study from October 2015 to October 2017.

Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro.

Introduction: Herpetic keratitis caused by the herpes simplex virus (HSV) is the most common form of ocular herpes that causes corneal blindness. Although treatments for herpes keratitis have improved in recent years. there is still considerable room for new treatments against viral infection that shows great promise.

Exploring the Biomechanical Properties of the Human Cornea Based on Corvis ST.

The aim of this study was to provide a method to determine corneal nonlinear viscoelastic properties based on the output data of corneal visualization Scheimpflug technology (Corvis ST). The Corvis ST data from 18 eyes of 12 healthy humans were collected. Based on the air-puff pressure and the corneal displacement from the Corvis ST test of normal human eyes, the work done by the air-puff attaining the whole corneal displacement was obtained.

Evaluation of preoperative dry eye in people undergoing corneal refractive surgery to correct myopia.

Aim: To investigate the incidence of preoperative dry eye and related factors in patients undergoing corneal refractive surgery to correct myopia.

Methods: A total of 141 patients with myopia who underwent corneal refractive surgery were surveyed by questionnaires, tear film break-up time (BUT) test, Schimer I test (SIt), corneal fluorescein staining (FL) test and diagnosed according to the currently recognized domestic diagnostic criteria for dry eye. Correlation analysis of factors such as age, gender, regular wearing of contact lens (CL), diopter (spherical equivalent), corneal thickness, and corneal curvature that may affect the onset of dry eye was carried out to clarify the main influencing factors.

Comparison of corneal curvature parameters obtained from two different instruments-Pentacam and VX120.

Aim: To explore whether the same corneal curvature parameters and anterior chamber depth measured by Pentacam and VX120 have a good consistency and can replace each other.

Methods: This study enrolled 140 eyes of 70 patients ranging in age from 19 to 53y. All eyes underwent a comprehensive ophthalmologic examination including an anterior segment analysis with the VX120 system (Visionix-Luneau Technologies, Chartres, France) and Pentacam (Oculus Optikgerate GmbH) respectively.

Comparison of corneal flaps created by Wavelight FS200 and Intralase FS60 femtosecond lasers.

Aim: To assess and compare the morphology of corneal flaps created by the Wavelight FS200 and Intralase FS60 femtosecond lasers in laser in situ keratomileusis (LASIK).

Methods: Four hundred eyes of 200 patients were enrolled in this study and divided into Wavelight FS200 groups (200 eyes) and Intralase FS60 groups (200 eyes). Fourier-domain optical coherence tomography (RTVue OCT) was used to measure the corneal flap thickness of 36 specified measurements on each flap one week after surgery.

Comparison of laser in situ keratomileusis flaps created by 2 femtosecond lasers.

Purpose: To compare flap morphology created by the WaveLight FS200 femtosecond laser and the VisuMax femtosecond laser, assessing the uniformity, accuracy, and predictability of flap creation.

Methods: A total of 400 eyes had corneal flaps created with the WaveLight FS200 femtosecond laser (200 eyes) or the VisuMax femtosecond laser (200 eyes). The desired flap thickness was 110 μm.

Effect of suction on macular and retinal nerve fiber layer thickness during femtosecond lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis.

Purpose: To compare the effect of suction on macular and retinal nerve fiber layer thickness during femtosecond lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis (LASIK) with the Visumax FS system.

Setting: Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.

Design: Prospective comparative case series.

Comparison of Ziemer FEMTO LDV "Classic" and "Crystal Line" femtosecond laser flap quality by Fourier-domain optical coherence tomography.

Aim: To compare the regularity and accuracy of laser in situ keratomileusis (LASIK) flaps created by the Ziemer FEMTO LDV "Classic" (Ziemer "Classic") and Ziemer FEMTO LDV Crystal Line femtosecond laser (Ziemer Crystal Line).

Methods: Fourier-domain optical coherence tomography (RTVue OCT) was used to measure the morphology of 200 LASIK flaps of 100 consecutive patients created with the Ziemer Classic (100 flaps) or the Ziemer Crystal Line (100 flaps) at one week postoperatively. Flap thickness was evaluated at 36 specified measurement points on each flap.

Comparison of the flaps made by femtosecond laser and automated keratomes for sub-bowman keratomileusis.

Background: Thin-flap laser in situ keratomileusis (LASIK) is the new trend of refractive error correction surgery, the formation of corneal flap is crucial for a success of LASIK surgery. This study aimed to assess and compare the variations of LASIK flap created by the IntraLase femtosecond laser, Moria One Use-Plus SBK and Moria M2 Single-Use 90 µm-head microkeratome using Anterior segment optical coherence tomography (Visante OCT).

Methods: One hundred and sixty-one eyes of 81 consecutive patients were enrolled in this prospective study and randomly divided into three groups depending on the flap creation method: flap creation with the the IntraLase femtosecond laser (IntraLase group, 59 eyes), flap creation with the Moria One Use-Plus SBK (SBK group, 44 eyes), and flap creation with the Moria M2 Single-Use 90 µm-head microkeratome (M2SU90 group, 58 eyes).

Comparison of 2 femtosecond lasers for laser in situ keratomileusis flap creation.

Purpose: To compare the morphology of laser in situ keratomileusis (LASIK) flaps created by 2 femtosecond lasers.

Setting: Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China.

Design: Comparative case series.

Comparison of the Ziemer FEMTO LDV femtosecond laser and Moria M2 mechanical microkeratome.

Purpose: To assess and compare the dimensions of LASIK flaps created by the Ziemer FEMTO LDV "Classic" femtosecond (FS) laser and Moria M2 microkeratome with 110-μm head and -20 blade.

Methods: Seven hundred twenty eyes from 360 consecutive patients were enrolled in this study and divided into two groups of equal size for flap creation with the Ziemer LDV (FS laser group) and Moria M2 mechanical microkeratome (microkeratome group). Nominal flap thickness was 110 μm for all patients and for both devices.

Expression and functional evaluation of transient receptor potential channel 4 in bovine corneal endothelial cells.

We previously found that activation of purinergic receptors mobilizes Ca2+ and enhances bicarbonate transport in bovine corneal endothelial cells (BCEC). Since transient receptor potential channel 4 (TRPC) has been reported to be a candidate for capacitative calcium entry (CCE) and receptor operated calcium entry (ROC), we examined the expression of TRPC4 and evaluated the potential involvement of TRPC4 in CCE or ROC in BCEC. The C-terminus of TRPC4 was fused into the glutathione S-transferase (GST) expression vector.