Identification of ferroptosis-related genes in the progress of NASH.

Background: Non-alcoholic steatohepatitis (NASH) is becoming more widespread, and some similarities exist between its etiology and ferroptosis. However, there are limited investigations on which ferroptosis-related genes (FRGs) are regulated in NASH and how to regulate them. We screened and validated the pivotal genes linked to ferroptosis in NASH to comprehend the function of ferroptosis in the development of NASH.

LncRNA LINC02257: A Potential Biomarker for Diagnosis and Prognosis of Colorectal Cancer.

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer mortality worldwide. However, efficient markers for CRC diagnosis are limited. Accumulating evidence reveals that long noncoding RNAs (lncRNAs) are related to the genesis and developments of many tumors.

Influence of Humidity on the Elastic Modulus and Axis Compressive Strength of Concrete in a Water Environment.

Concrete structures are often in different humidity conditions that have a significant impact on the elastic modulus of concrete, therefore, systematic research on the evolution of the law of concrete elastic modulus under different humidity conditions is needed. In this study, the variation laws of the water saturation of concrete specimens with strength grades C15, C20, and C30 were obtained, and then the influence laws of the water saturation on the concrete axial compressive strength were carried out, and the prediction model of elastic modulus of concrete with respect to water saturation was constructed. The results showed that the water saturation of concrete with strength grades C15, C20, and C30 increased with an extension of immersion time, and the water saturation showed an approximately linear rapid growth within three soaking hours, reaching 47.

Influencing Factors for Sleep Quality Among Shift-working Nurses: A Cross-Sectional Study in China Using 3-factor Pittsburgh Sleep Quality Index.

Purpose: The aim of this study was to identify influencing factors for sleep quality among shift-working nurses based on a three-factor scoring model that included sleep efficacy, sleep quality and daily dysfunction.

Methods: A cross-sectional survey of 513 nurses in a hospital in Shanghai, China, was conducted using a self-reported questionnaire. Sleep quality was measured by the Pittsburgh Sleep Quality Index (PSQI).

Knowledge and attitude towards menopause and hormone replacement therapy in Chinese women.

Objective: To explore the knowledge and prevalence of menopausal symptoms as well as the use and attitude toward hormone replacement therapy (HRT) in Chinese women.

Methods: A cross-sectional study was conducted between May 2011 and April 2012 in Shanghai, China. The structured questionnaire addressing sociodemographic characteristics, knowledge and prevalence of menopausal symptoms, and knowledge and attitude towards HRT and its use were investigated.

Correlation between the modified Kupperman Index and the Menopause Rating Scale in Chinese women.

Background: The severity of menopausal symptoms can vary according to ethnicity and geography. Two common menopausal symptom scales, the modified Kupperman Index (KI) and the Menopausal Rating Scale (MRS), are accepted internationally. In this study, we evaluated the correlation between these scales and their relevance to women in the People's Republic of China.