Publications by authors named "Chang-yin Shen"
[Establishing an animal model for carotid artery stenosis in rabbits].
Sichuan Da Xue Xue Bao Yi Xue Ban
September 2009
Article Synopsis
- A study aimed to create a rabbit model for carotid artery stenosis by using nitrogen gas injury and a high cholesterol diet.
- Recently, rabbits developed early to advanced stages of atherosclerosis, with notable artery stenosis observed through angiography at both 4 and 8 weeks post-injury.
- The research concluded that this model effectively mimics carotid artery stenosis, allowing for further investigation into related conditions.
Objective: To investigate the effect of rhG-CSF on mobilizing bone marrow-MSCs, re-endothelialization and intima hyperplasia in carotid artery of rabbits post balloon catheter injury.
Methods: Rabbits were treated with rhG-CSF (25 microg/kg, twice daily, i.p, n = 35) or saline (n = 32) for 5 days, then, carotid arteries of rabbits were injured by balloon catheter.