Hepatocyte growth factor enhances the ability of dental pulp stem cells to ameliorate atherosclerosis in apolipoprotein E-knockout mice.

Background: Atherosclerosis (AS), a chronic inflammatory disease of blood vessels, is a major contributor to cardiovascular disease. Dental pulp stem cells (DPSCs) are capable of exerting immunomodulatory and anti-inflammatory effects by secreting cytokines and exosomes and are widely used to treat autoimmune and inflammation-related diseases. Hepatocyte growth factor (HGF) is a pleiotropic cytokine that plays a key role in many inflammatory and autoimmune diseases.

Inactivation of biofilms by thymoquinone in combination with nisin.

is one of the most important foodborne pathogens that can persist in leafy green vegetables and subsequently produce biofilms. In this study, the synergistic effect of thymoquinone and nisin in reducing biofilm formation of on lettuce was evaluated, and their anti-virulence and anti-biofilm mechanisms were also investigated. At concentrations ranging from 0.

Micrometer-Sized Titanium Particles Induce Aseptic Loosening in Rabbit Knee.

Wear debris induced aseptic loosening is the leading cause of total knee arthroplasty (TKA) failure. The complex mechanism of aseptic loosening has been a major issue for introducing effective prevention and treatment methods, so a simplified yet efficient rabbit model was established to address this concern with the use of micrometer-sized titanium particles. 20 New Zealand white rabbits were selected and divided into two groups (control = 10, study = 10).

Astragaloside IV suppresses inflammatory mediator production in synoviocytes and collagen‑induced arthritic rats.

The aim of the current study was to investigate the effects of Astragaloside‑IV (AS‑IV) on inflammatory mediators in synoviocytes and collagen‑induced arthritic rats. Synoviocytes were stimulated with lipopolysaccharides (LPS) and Sprague‑Dawley rats were injected with type II collagen. AS‑IV was administered to the LPS‑stimulated synoviocytes and collagen‑induced arthritis (CIA) rats.

Crop Classification Based on Time Series MODIS EVI and Ground Observation for Three Adjoining Years in Xinjiang.

There is a regular use of Moderate Resolution Imaging Spectroradiometer (MODIS) 250 meter EVI to classify the crops on a regional level throughout the world. A rapid agricultural land use change attributed to new Chinese agriculture policy is attracting many researchers to focus. The objective of this study is to present a more straightforward multiyear classification methodology using time series MODIS EVI with 250 meters spatial resolution and subsequent field data in Xinjiang, China.

[Repair full-thickness meniscal defects with injectable tissue engineering technique].

Objective: To investigate the effectiveness of injectable tissue engineering to repair full-thickness meniscal defects.

Methods: From June 2008 to February 2009 full-thickness of meniscal defects were created in the anterior corner of goats, which with no blood supply, in a diameter of 2 mm. Then bone marrow stem cells (BMSCs) was mixed with injectable calcium alginate gel to fill the defects.

[The efficacy of open-wedge high tibial osteotomy for varus knee].

Objective: To introduce the biplanar opening high tibial osteotomy with rigid fixation for adult varus knee.

Methods: Twelve patients with varus knee and degeneration of medial compartment received the biplanar opening high tibial osteotomy between June 2001 and July 2008. The pre-operative deformity was about 11.

Modified biplanar open-wedge high tibial osteotomy with rigid locking plate to treat varus knee.

Objective: To introduce and characterize the modified biplanar opening high tibial osteotomy with rigid fixation to treat varus knee in young and active patients.

Methods: Between June 2001 to July 2008, 18 patients with monocompartmental degeneration of the knee combined with a varus malalignment of the leg had the modified biplanar opening high tibial osteotomy and the osteotomy was fixed with the locking plates (Locking Compression Plate System). The mean varus deformity before operation was 11.