Measuring physical observables requires averaging experimental outcomes over numerous identical measurements. The complete distribution function of possible outcomes or its Fourier transform, known as the full counting statistics, provides a more detailed description. This method captures the fundamental quantum fluctuations in many-body systems and has gained significant attention in quantum transport research.
View Article and Find Full Text PDFBackground: Monogenic lupus is defined as systemic lupus erythematosus (SLE)/SLE-like patients with either dominantly or recessively inherited pathogenic variants in a single gene with high penetrance. However, because the clinical phenotype of monogenic SLE is extensive and overlaps with that of classical SLE, it causes a delay in diagnosis and treatment. Currently, there is a lack of early identification models for clinical practitioners to provide early clues for recognition.
View Article and Find Full Text PDFThe 2D Hubbard model with large repulsion is an important problem in condensed matter physics. At half filling, its ground state is an antiferromagnet (AMF). The dope AMF below half filling is believed to capture the physics of highsuperconductors.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
May 2023
Purpose: The detection of human epidermal growth factor receptor 2 (HER2) expression status is essential to determining the chemotherapy regimen for breast cancer patients and to improving their prognosis. We developed a deep learning radiomics (DLR) model combining time-frequency domain features of ultrasound (US) video of breast lesions with clinical parameters for predicting HER2 expression status.
Patients And Methods: Data for this research was obtained from 807 breast cancer patients who visited from February 2019 to July 2020.
Background: Recombinant human growth hormone (rhGH) therapy has shown to improve height and body composition in children with Prader-Willi syndrome (PWS), the evidence of early rhGH treatment on motor and mental development is still accumulating. This study explored the time effect on psychomotor development, anthropometric indexes, and safety for infants and young children with PWS.
Methods: A phase 3, single-arm, multicenter, self-controlled study was conducted in six sites.
J Phys Condens Matter
September 2022
The compact groups such as() and() groups have been heavily studied and applied in the study of quantum many body systems. However, the non-compact groups such as the real symplectic groups are less touched. In this paper, it is revealed that the quantum dynamics of two-component Bose-Einstein condensate can be described by a non-compact real symplectic groupSp(4,R).
View Article and Find Full Text PDFA hypoxic microenvironment is a common feature of skin wounds. Our previous study demonstrated that three-dimensional coculture of umbilical cord-derived mesenchymal stem cells (ucMSCs) and endothelial cells facilitates cell communication and host integration in skin tissue engineering. Here, we aimed to identify the mechanism by which ucMSCs affect endothelial cells under hypoxic conditions after skin injury.
View Article and Find Full Text PDFObjective: To investigate the incidence rate of infectious diseases during hospitalization in late preterm infants in Beijing, China, as well as the risk factors for infectious diseases and the effect of breastfeeding on the development of infectious diseases.
Methods: Related data were collected from the late preterm infants who were hospitalized in the neonatal wards of 25 hospitals in Beijing, China, from October 23, 2015 to October 30, 2017. According to the feeding pattern, they were divided into a breastfeeding group and a formula feeding group.
Objective: To report the clinical features of patients with systemic lupus erythematosus (SLE) associated with thrombotic thrombocytopenic purpura (TTP). Their diagnosis, treatment, and prognosis were also discussed.
Methods: A total of 25 TTP-SLE pediatric patients were included in this study.
Hopf insulators are characterized by a topological invariant called the Hopf index which classifies maps from three-sphere to two-sphere, instead of a Chern number or a Chern parity. In contrast to a topological insulator, the Hopf insulator is not protected by any kind of symmetry. By dimensional reduction, we argue that there exists a new type of Z(2) index for 2D Hamiltonian with a vanishing Chern number.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
May 2014
The clinical data of three Chinese children who had been definitely diagnosed with X-link dominate hypophosphatemic rickets (XLH) by gene mutation analysis of phosphate-regulating gene with homologies to endopeptidases on the X chromosome (PHEX) were retrospectively studied and the relevant literature was reviewed. PHEX gene mutations were detected in all 3 XLH children; a nonsense mutation (c.58C>T) in one case and splicing mutations (c.
View Article and Find Full Text PDFWeight gain commonly occurs in breast cancer patients who receive adjuvant chemotherapy. Weight gain may cause psychosocial stress and is associated with patient prognosis and survival. Several factors contributing to weight gain have been identified in Western populations.
View Article and Find Full Text PDFZhonghua Er Ke Za Zhi
September 2013
Objective: The purpose of this study was to investigate the clinical and genetic characteristics of autosomal recessive polycystic kidney disease.
Method: Targeted sequencing was used on a children who was accurately diagnosed as autosomal recessive polycystic kidney disease in Peking Union Medical College Hospital to analyze the major clinical manifestations of the disease. An analysis of the PKHD1 genes was made on the patient, and then verified by polymerase chain reaction (PCR).