National-wide survey of ophthalmic human resources in China in 2021.

Purpose: To evaluate the availability of human resources for ophthalmic services in mainland China.

Methods: In 2021, we conducted a nationwide survey of ophthalmic outpatient services across 2996 tertiary hospitals and 10,404 secondary hospitals in 31 provinces in mainland China.

Results: The response rate was 73.

Ten-year evaluation on efficacy, safety, and predictability of femtosecond laser corneal small incision lenticule extraction for correction of myopia and myopic astigmatism: a case series.

Objective: The objective was to evaluate the 10-year long-term outcomes of patients undergoing small incision lenticule extraction (SMILE).

Methods: In this continuous case series, the authors enrolled a total of 113 patients (208 eyes) who underwent SMILE 10 years prior. Measured parameters included uncorrected visual acuity (UCVA), corrected distance visual acuity (CDVA), and cycloplegia spherical equivalent error (SER).

Effects of atropine eyedrops at ten different concentrations for myopia control in children: A systematic review on meta-analysis.

Purpose: To estimate the effect of atropine eyedrops at different concentrations for myopia control in children.

Methods: We conducted a Bayesian random-effects network meta-analysis based on randomized controlled trials (RCT). Primary outcomes include changes in spherical equivalent error (SER) and changes in axial length (AL), mean difference (MD) together with 95% credible interval (CrI) were used to evaluate the efficacy.

An auxiliary diagnostic tool for common fundus diseases based on fundus color photography and light-weight classification models.

Objective: To evaluate the performance of two lightweight neural network models in the diagnosis of common fundus diseases and make comparison to another two classical models.

Methods: A total of 16,000 color fundus photography were collected, including 2000 each of glaucoma, diabetic retinopathy (DR), high myopia, central retinal vein occlusion (CRVO), age-related macular degeneration (AMD), optic neuropathy, and central serous chorioretinopathy (CSC), in addition to 2000 normal fundus. Fundus photography was obtained from patients or physical examiners who visited the Ophthalmology Department of Beijing Tongren Hospital, Capital Medical University.

Six-month repeated irradiation of 650 nm low-level red light reduces the risk of myopia in children: a randomized controlled trial.

Purpose: To evaluate whether the six-month repeated irradiation of 650 nm low-level red light (LLRL) decreases the risk of myopia onset in children.

Methods: This was a single-masked, randomized controlled trial. A total of 112 children (aged 6-12 years) were enrolled and randomized to the treatment group or control group in a 1:1 ratio.

Association between dosing of spironolactone and outcomes in heart failure with preserved ejection fraction patients combined with chronic kidney disease------Balance of efficacy and risk.

Few studies have compared the association between dosing of spironolactone and outcomes in patients with heart failure with preserved ejection fraction (HFpEF), and whether spironolactone dose could significantly affect the prognosis of HFpEF patients combined with chronic kidney disease (CKD) remains unclear. Our aim was to directly compare 'high vs. low' doses of spironolactone in an attempt to find a benefit-risk-balanced point, and infer an adequate dose for HFpEF with CKD patients.

Investigation of the Efficacy and Safety of 650 nm Low-Level Red Light for Myopia Control in Children: A Randomized Controlled Trial.

Introduction: To evaluate the 6-month efficacy and safety of 650 nm low-level red light (LLRL) for myopia control in children.

Methods: This was a single-center, single-masked randomized controlled trial. A total of 224 children aged 6-12 years with spherical equivalent error (SER) of - 6 diopter (D) to - 0.

[Curcumin improves cardiac fibrosis by inhibiting endothelial-mesenchymal transition through NRF2-DDAH-ADMA-NO pathway].

The present study analyzed the correlations between curcumin(Cur), nuclear factor E2 related factor 2(NRF2)-dimethylarginine dimethylaminohydrolase(DDAH)-asymmetric dimethylarginine(ADMA)-nitric oxide(NO) pathway, and endothelial-mesenchymal transition(EndMT) based on SD rats with cardiac fibrosis, and explored the effect and mechanism of Cur in resisting cardiac fibrosis to provide an in-depth theoretical basis for its clinical application in the treatment of heart failure. The cardiac fibrosis model was induced by subcutaneous injection of isoprenaline(Iso) in rats. Thirty-two rats were randomly divided into a control group, a model group, a low-dose Cur group(100 mg·kg~(-1)·d~(-1)), and a high-dose Cur group(200 mg·kg~(-1)·d~(-1)), with eight in each group.

Clinical Impact of Thrombus Aspiration and Interaction With D-Dimer Levels in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

To evaluate the effect of thrombus aspiration (TA) strategy on the outcomes and its interaction with D-dimer levels in patients with ST-segment elevation myocardial infarction (STEMI) during primary percutaneous coronary intervention (PCI) in "real-world" settings. This study included 1,295 patients with STEMI who had undergone primary PCI with or without TA between January 2013 and June 2017. Patients were first divided into a TA+PCI group and a PCI-only group, and the baseline characteristics and long-term mortality between the two groups were analyzed.

Effect of lens capsular tension ring on preventing capsular contraction syndrome in the surgery of retinitis pigmentosa combined with cataract: Retrospective case series.

Purpose: To observe the effect of phacoemulsification and intraocular lens (IOL) implantation with or without lens capsular tension ring (CTR) on retinitis pigmentosa (RP) combined with cataract patients.

Design: Retrospective cases series study.

Methods: Sixty-three cases (84 eyes) of RP with cataract were collected, including 30 males and 33 females.

Diagnostic Value of Optical Coherence Tomography Angiography for Choroidal Neovascularization in Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis.

Objective: This study aims to evaluate the diagnostic value of optical coherence tomography angiography (OCTA) in detecting the choroidal neovascularization (CNV) in age-related macular degeneration (AMD).

Methods: A systematic review and meta-analysis was performed by searching Pubmed, Science Direct, Embase, and Web of Science. The pooled sensitivity and specificity with 95% confidence intervals (CIs), area under the summary receiver operator characteristic curve (sROC), and the total accurate classification rate were used to evaluate OCTA's diagnostic value of CNV in AMD patients.

Horizontal and vertical optic disc rotation. The Beijing Eye Study.

Purpose: To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters.

Design: Population-based study.

Methods: In the Beijing Eye Study, 3468 participants (mean age:64.

Possible association between Helicobacter pylori infection and nonalcoholic fatty liver disease.

Possible association between Helicobacter pylori infection (HPI) and nonalcoholic fatty liver disease (NAFLD) has been proposed by several studies with inconsistent conclusions. Here, we studied the association between HPI and NAFLD at 3 levels: (i) genetic level; (ii) small molecular level; and (iii) clinical level. Relation data between diseases, genes, and small molecules were acquired from Pathway Studio ResNet Mammalian database.

Association between choroidal thickness and anterior chamber segment in eyes with narrow or open-angle.

Aim: To investigate the relationship between choroidal thickness and anterior chamber segment in subjects with eyes with narrow or open-angle.

Methods: The subfoveal choroidal thickness was measured with enhanced depth-imaging optical coherence tomography and anterior chamber parameters were measured with ultrasound biomicroscopy in one eye of 23 subjects with open-angle eyes and 38 subjects with narrow-angle eyes. The mean age was 59.

Prevalence and associations of central serous chorioretinopathy in elderly Chinese. The Beijing Eye Study 2011.

Purpose: To determine the prevalence and associations of central serous chorioretinopathy (CSC) in elderly Chinese.

Methods: The population-based cross-sectional Beijing Eye Study 2011 included 3468 individuals (age: 64.6 ± 9.

MACULAR BRUCH MEMBRANE DEFECTS IN HIGHLY MYOPIC EYES: The Beijing Eye Study.

Purpose: To examine prevalence and associations of macular Bruch membrane defects (MBMDs) in a population-based setting.

Design: Population-based cross-sectional study.

Methods: The Beijing Eye Study 2011 included 3,468 subjects who underwent a detailed ophthalmic examination including spectral domain optical coherence tomography with enhanced depth imaging of the macula.

Subfoveal choroidal thickness and cataract: the Beijing Eye Study 2011.

Purpose: This study examined subfoveal choroidal thickness (SFCT) in eyes with cataracts.

Methods: The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6 ± 9.

Visual acuity and subfoveal choroidal thickness: the Beijing Eye Study.

Purpose: To examine the association between best corrected visual acuity (BCVA) and subfoveal choroidal thickness.

Design: Population-based study.

Methods: The Beijing Eye Study 2011 included 3468 subjects with ages of 50+ years.

Non-alcoholic fatty liver disease and risk of in-stent restenosis after bare metal stenting in native coronary arteries.

In-stent restenosis (ISR) remains the most common complication of percutaneous coronary intervention. Due to shared risk factors, it is postulated that non-alcoholic fatty liver disease (NAFLD) patients have an increased risk of ISR. This study aimed to determine the association between NAFLD and ISR in patients after bare metal stenting.

Peripapillary intrachoroidal cavitations. The Beijing eye study.

Purpose: To assess prevalence, size and location of peripapillary intrachoroidal cavitations (PICCs) and their associations in a population-based sample. .

Methods: The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.

Localized retinal nerve fiber layer defects detected by optical coherence tomography: the Beijing eye study.

Objective: To assess the prevalence of localized retinal nerve fiber layer defects (LRNFLD) and associated factors in adult Chinese.

Methods: The population-based Beijing Eye Study 2011 included 3468 individuals (mean age: 64.6±9.

Myopic maculopathy imaged by optical coherence tomography: the beijing eye study.

Purpose: To examine the features of myopia-related optical coherence tomography (OCT) findings in a population-based setting.

Design: Population-based study.

Participants: The Beijing Eye Study 2011 included 3468 subjects with an age of 50 years or more.