Publications by authors named "Chang-li Gong"
Background: Hyperbaric oxygen (HBO) and Ginkgo biloba extract (e.g., EGB 761) were shown to ameliorate cognitive and memory impairment in Alzheimer's disease (AD).
View Article and Find Full Text PDF[Experimental study of inhibition of safflower injection on mesenteric microvascular motion in rabbits DI].
Zhongguo Zhong Xi Yi Jie He Za Zhi
April 2007
Objective: To dynamically observe the effect of Safflower Injection (SI) on mesenteric microvascular motion in vivo in rabbits, and to explore the effect of nitric oxide (NO) in the process to further investigate the action mechanism of activating blood to remove stasis of SI.
Methods: Twenty healthy male albino rabbits were intraperitoneally injected with urethane for basic anesthesia and injected with alpha-chloralose via ear marginal venous to maintain anesthesia, spontaneously ventilated via tracheotomy tube, with the in-step record of breath and blood pressure. The vasomotion was induced by noradrenaline (NA) in vivo, then the changes of vasomotion after injecting SI and N(G)-monomethyl-L-arginine (L-NMMA, a NO synthase inhibitor) were measured respectively on a TV monitor using a TV camera mounted on the microscope, and the influence of L-NMMA on effect of SI was also observed.
Article Synopsis
- The study aimed to investigate the link between vitamin D receptor (VDR) gene polymorphisms and autoimmune liver diseases, specifically autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC), in a Chinese population.
- Using PCR-RELP, researchers analyzed VDR polymorphisms in patients and healthy controls, finding significant differences in VDR gene variants between AIH/PBC patients and healthy individuals.
- The results indicate that specific VDR polymorphisms, particularly FokI and BsmI, are associated with an increased risk of AIH and PBC in the Chinese population, differing from trends observed in Caucasian groups.