Association between P-glycoprotein expression and response to chemotherapy in patients with osteosarcoma: a systematic and meta-analysis.

Objective: The aim was to investigate the association between p-glycoprotein (Pgp) expression and response to chemotherapy in patients with osteosarcoma.

Materials And Methods: We searched and included the openly published articles evaluated the correlation between Pgp expression and response to chemotherapy. The odds ratio (OR) of response rate for Pgp positive group versus Pgp negative group was aggregated by random or fixed effect model.

Treatment for severe idiopathic upper thoracic scoliosis in adolescence.

Study Design: To review the study of severe upper thoracic scoliosis (>90 degrees) in adolescence treated with pedicle screw constructs.

Objective: The purpose of the present study was to analyze the treatment for upper thoracic scoliosis in adolescence.

Summary Of Background Data: Upper thoracic scoliosis is an uncommon spinal deformity in young children.

A case report of a metastatic gastrointestinal stromal tumor occurring in femur.

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms that most commonly affect the stomach or small intestine, but can occur anywhere throughout the gastrointestinal tract. To the best of our knowledge, few cases have been reported in the literature about the femur metastasis of GIST. This paper describes a metastasis of a gastrointestinal stromal tumour (GIST) to the femur in a 62-year-old male, 2 years after treatment for a gastric primary.